"Dihydroxyphenylalanine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
| Descriptor ID |
D004295
|
| MeSH Number(s) |
D02.092.311.200 D12.125.072.050.685.400 D12.125.072.050.875.130
|
| Concept/Terms |
Dihydroxyphenylalanine- Dihydroxyphenylalanine
- beta-Hydroxytyrosine
- beta Hydroxytyrosine
- 3-Hydroxy-DL-tyrosine
- 3 Hydroxy DL tyrosine
- 3,4-Dihydroxyphenylalanine
- 3,4 Dihydroxyphenylalanine
- Dopa
|
Below are MeSH descriptors whose meaning is more general than "Dihydroxyphenylalanine".
Below are MeSH descriptors whose meaning is more specific than "Dihydroxyphenylalanine".
This graph shows the total number of publications written about "Dihydroxyphenylalanine" by people in this website by year, and whether "Dihydroxyphenylalanine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dihydroxyphenylalanine" by people in Profiles.
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Efficacy and safety of standardized extract of Trigonella foenum-graecum L seeds as an adjuvant to L-Dopa in the management of patients with Parkinson's disease. Phytother Res. 2014 Feb; 28(2):172-8.
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Lewy body pathology in fetal grafts. Ann N Y Acad Sci. 2010 Jan; 1184:55-67.
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A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease. Ann Neurol. 2003 Sep; 54(3):403-14.
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Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science. 2000 Oct 27; 290(5492):767-73.
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Comparison of the neurotoxicity of dihydroxyphenylalanine stereoisomers in cultured dopamine neurons. Clin Neuropharmacol. 1996 Aug; 19(4):360-5.