 Actins
"Actins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
| Descriptor ID |
D000199
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| MeSH Number(s) |
D05.750.078.730.250 D12.776.210.500.100 D12.776.220.525.255
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Actins".
Below are MeSH descriptors whose meaning is more specific than "Actins".
This graph shows the total number of publications written about "Actins" by people in this website by year, and whether "Actins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1982 | 0 | 1 | 1 | | 1990 | 1 | 1 | 2 | | 1993 | 0 | 1 | 1 | | 2000 | 1 | 1 | 2 | | 2001 | 2 | 0 | 2 | | 2002 | 1 | 0 | 1 | | 2003 | 2 | 3 | 5 | | 2004 | 1 | 1 | 2 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 2 | 2 | | 2007 | 2 | 2 | 4 | | 2008 | 1 | 2 | 3 | | 2009 | 2 | 1 | 3 | | 2010 | 1 | 4 | 5 | | 2011 | 0 | 2 | 2 | | 2012 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 2 | 1 | 3 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 0 | 2 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Actins" by people in Profiles.
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Polat OK, Uno M, Maruyama T, Tran HN, Imamura K, Wong CF, Sakaguchi R, Ariyoshi M, Itsuki K, Ichikawa J, Morii T, Shirakawa M, Inoue R, Asanuma K, Reiser J, Tochio H, Mori Y, Mori MX. Contribution of Coiled-Coil Assembly to Ca2+/Calmodulin-Dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-Associated Phenotypes. J Am Soc Nephrol. 2019 09; 30(9):1587-1603.
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Kommaddi RP, Das D, Karunakaran S, Nanguneri S, Bapat D, Ray A, Shaw E, Bennett DA, Nair D, Ravindranath V. Aß mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease. J Neurosci. 2018 01 31; 38(5):1085-1099.
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Reiser J, Lee HW, Gupta V, Altintas MM. A High-Content Screening Technology for Quantitatively Studying Podocyte Dynamics. Adv Chronic Kidney Dis. 2017 05; 24(3):183-188.
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Kataria Y, Deaton RJ, Enk E, Jin M, Petrauskaite M, Dong L, Goldenberg JR, Cotler SJ, Jensen DM, van Breemen RB, Gann PH. Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer. BMC Gastroenterol. 2016 Feb 29; 16:30.
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Lee HW, Khan SQ, Faridi MH, Wei C, Tardi NJ, Altintas MM, Elshabrawy HA, Mangos S, Quick KL, Sever S, Reiser J, Gupta V. A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules. J Am Soc Nephrol. 2015 Nov; 26(11):2741-52.
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Lam PY, Mangos S, Green JM, Reiser J, Huttenlocher A. In vivo imaging and characterization of actin microridges. PLoS One. 2015; 10(1):e0115639.
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Li M, Armelloni S, Zennaro C, Wei C, Corbelli A, Ikehata M, Berra S, Giardino L, Mattinzoli D, Watanabe S, Agostoni C, Edefonti A, Reiser J, Messa P, Rastaldi MP. BDNF repairs podocyte damage by microRNA-mediated increase of actin polymerization. J Pathol. 2015 Apr; 235(5):731-44.
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Joy A, Al-Ghoul KJ. Basal membrane complex architecture is disrupted during posterior subcapsular cataract formation in Royal College of Surgeons rats. Mol Vis. 2014; 20:1777-95.
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Müller-Krebs S, Kihm LP, Madhusudhan T, Isermann B, Reiser J, Zeier M, Schwenger V. Human RAGE antibody protects against AGE-mediated podocyte dysfunction. Nephrol Dial Transplant. 2012 Aug; 27(8):3129-36.
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Yin P, Navarro A, Fang F, Xie A, Coon JS, Richardson C, Bulun SE. Early growth response-2 expression in uterine leiomyoma cells: regulation and function. Fertil Steril. 2011 Aug; 96(2):439-44.
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