"Actins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
| Descriptor ID |
D000199
|
| MeSH Number(s) |
D05.750.078.730.250 D12.776.210.500.100 D12.776.220.525.255
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Actins".
Below are MeSH descriptors whose meaning is more specific than "Actins".
This graph shows the total number of publications written about "Actins" by people in this website by year, and whether "Actins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 0 | 1 |
| 2003 | 2 | 2 | 4 |
| 2004 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 1 | 2 |
| 2010 | 0 | 4 | 4 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Actins" by people in Profiles.
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Alterations of?housekeeping?proteins in human aged and diseased hearts. Pflugers Arch. 2021 03; 473(3):351-362.
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Contribution of Coiled-Coil Assembly to Ca2+/Calmodulin-Dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-Associated Phenotypes. J Am Soc Nephrol. 2019 09; 30(9):1587-1603.
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A? mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease. J Neurosci. 2018 01 31; 38(5):1085-1099.
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A High-Content Screening Technology for Quantitatively Studying Podocyte Dynamics. Adv Chronic Kidney Dis. 2017 05; 24(3):183-188.
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Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer. BMC Gastroenterol. 2016 Feb 29; 16:30.
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A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules. J Am Soc Nephrol. 2015 Nov; 26(11):2741-52.
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In vivo imaging and characterization of actin microridges. PLoS One. 2015; 10(1):e0115639.
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BDNF repairs podocyte damage by microRNA-mediated increase of actin polymerization. J Pathol. 2015 Apr; 235(5):731-44.
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Basal membrane complex architecture is disrupted during posterior subcapsular cataract formation in Royal College of Surgeons rats. Mol Vis. 2014; 20:1777-95.
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Human RAGE antibody protects against AGE-mediated podocyte dysfunction. Nephrol Dial Transplant. 2012 Aug; 27(8):3129-36.