"Tensins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of multidomain microfilament proteins that bind ACTIN FILAMENTS and INTEGRINS at FOCAL ADHESIONS. They generally consist of an N-terminal domain with homology to PHOSPHOTYROSINE PHOSPHATASE, a C2 DOMAIN; unique central regions rich in PROLINE; ALANINE; GLYCINE; and SERINE; an SH2 DOMAIN; and a C-terminal phosphotyrosine-binding region. They are involved in CELL MIGRATION; CELL ADHESION; SIGNAL TRANSDUCTION; and reorganization of the CYTOSKELETON.
| Descriptor ID |
D000070876
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| MeSH Number(s) |
D05.750.078.730.719 D12.776.220.525.719
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tensins".
Below are MeSH descriptors whose meaning is more specific than "Tensins".
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Below are the most recent publications written about "Tensins" by people in Profiles.