Actin Depolymerizing Factors
"Actin Depolymerizing Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.
| Descriptor ID |
D051339
|
| MeSH Number(s) |
D05.750.078.730.212 D12.776.220.525.212
|
| Concept/Terms |
Actin Depolymerizing Factors- Actin Depolymerizing Factors
- Depolymerizing Factors, Actin
- Cofilins
- Cofilin Proteins
- Actin Depolymerizing Proteins
- Depolymerizing Proteins, Actin
- ADF Proteins (Actin Depolymerizing Factors)
|
Below are MeSH descriptors whose meaning is more general than "Actin Depolymerizing Factors".
Below are MeSH descriptors whose meaning is more specific than "Actin Depolymerizing Factors".
This graph shows the total number of publications written about "Actin Depolymerizing Factors" by people in this website by year, and whether "Actin Depolymerizing Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Actin Depolymerizing Factors" by people in Profiles.
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A? mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease. J Neurosci. 2018 01 31; 38(5):1085-1099.
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BDNF repairs podocyte damage by microRNA-mediated increase of actin polymerization. J Pathol. 2015 Apr; 235(5):731-44.
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Cofilin aggregation blocks intracellular trafficking and induces synaptic loss in hippocampal neurons. J Biol Chem. 2012 Feb 03; 287(6):3919-29.