 Ryanodine
"Ryanodine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.
| Descriptor ID |
D012433
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| MeSH Number(s) |
D02.455.849.291.686 D03.132.740 D03.383.129.578.805
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ryanodine".
Below are MeSH descriptors whose meaning is more specific than "Ryanodine".
This graph shows the total number of publications written about "Ryanodine" by people in this website by year, and whether "Ryanodine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1988 | 0 | 1 | 1 | | 1989 | 1 | 0 | 1 | | 1992 | 0 | 1 | 1 | | 1993 | 0 | 3 | 3 | | 1994 | 0 | 2 | 2 | | 1996 | 1 | 1 | 2 | | 1998 | 0 | 2 | 2 | | 2003 | 0 | 1 | 1 | | 2005 | 0 | 2 | 2 | | 2008 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ryanodine" by people in Profiles.
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R?os E. On an early demonstration of the cell boundary theorem. J Physiol Sci. 2013 Mar; 63(2):161.
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Porta M, Diaz-Sylvester PL, Nani A, Ramos-Franco J, Copello JA. Ryanoids and imperatoxin affect the modulation of cardiac ryanodine receptors by dihydropyridine receptor Peptide A. Biochim Biophys Acta. 2008 Nov; 1778(11):2469-79.
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Xu L, Wang Y, Gillespie D, Meissner G. Two rings of negative charges in the cytosolic vestibule of type-1 ryanodine receptor modulate ion fluxes. Biophys J. 2006 Jan 15; 90(2):443-53.
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Wang Y, Xu L, Pasek DA, Gillespie D, Meissner G. Probing the role of negatively charged amino acid residues in ion permeation of skeletal muscle ryanodine receptor. Biophys J. 2005 Jul; 89(1):256-65.
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Cherednichenko G, Zima AV, Feng W, Schaefer S, Blatter LA, Pessah IN. NADH oxidase activity of rat cardiac sarcoplasmic reticulum regulates calcium-induced calcium release. Circ Res. 2004 Mar 05; 94(4):478-86.
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Satoh H, Katoh H, Velez P, Fill M, Bers DM. Bay K 8644 increases resting Ca2+ spark frequency in ferret ventricular myocytes independent of Ca influx: contrast with caffeine and ryanodine effects. Circ Res. 1998 Dec 14-28; 83(12):1192-204.
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McCall E, Ginsburg KS, Bassani RA, Shannon TR, Qi M, Samarel AM, Bers DM. Ca flux, contractility, and excitation-contraction coupling in hypertrophic rat ventricular myocytes. Am J Physiol. 1998 04; 274(4):H1348-60.
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Sierralta J, Fill M, Su?rez-Isla BA. Functionally heterogenous ryanodine receptors in avian cerebellum. J Biol Chem. 1996 Jul 19; 271(29):17028-34.
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Holda JR, Oberti C, Perez-Reyes E, Blatter LA. Characterization of an oxytocin-induced rise in [Ca2+]i in single human myometrium smooth muscle cells. Cell Calcium. 1996 Jul; 20(1):43-51.
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Tu Q, V?lez P, Brodwick M, Fill M. Streaming potentials reveal a short ryanodine-sensitive selectivity filter in cardiac Ca2+ release channel. Biophys J. 1994 Dec; 67(6):2280-5.
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