 Protein Binding
"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
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| MeSH Number(s) |
G02.111.087.680 G02.149.115.680 G03.495.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1982 | 0 | 1 | 1 | | 1985 | 0 | 1 | 1 | | 1986 | 0 | 2 | 2 | | 1988 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 2000 | 0 | 3 | 3 | | 2001 | 0 | 8 | 8 | | 2002 | 0 | 3 | 3 | | 2003 | 0 | 9 | 9 | | 2004 | 0 | 7 | 7 | | 2005 | 0 | 10 | 10 | | 2006 | 0 | 2 | 2 | | 2007 | 0 | 7 | 7 | | 2008 | 0 | 4 | 4 | | 2009 | 0 | 4 | 4 | | 2010 | 0 | 7 | 7 | | 2011 | 0 | 9 | 9 | | 2012 | 0 | 4 | 4 | | 2013 | 0 | 7 | 7 | | 2014 | 0 | 6 | 6 | | 2015 | 0 | 3 | 3 | | 2016 | 0 | 5 | 5 | | 2017 | 0 | 2 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 4 | 4 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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Kim Y, Liu G, Leugers CJ, Mueller JD, Francis MB, Hefti MM, Schneider JA, Lee G. Tau interacts with SHP2 in neuronal systems and in Alzheimer's disease brains. J Cell Sci. 2019 07 15; 132(14).
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Søndergaard MT, Liu Y, Brohus M, Guo W, Nani A, Carvajal C, Fill M, Overgaard MT, Chen SRW. Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations. FEBS J. 2019 11; 286(22):4554-4578.
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Skowron KJ, Booker K, Cheng C, Creed S, David BP, Lazzara PR, Lian A, Siddiqui Z, Speltz TE, Moore TW. Steroid receptor/coactivator binding inhibitors: An update. Mol Cell Endocrinol. 2019 08 01; 493:110471.
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Ríos E, Gillespie D, Franzini-Armstrong C. The binding interactions that maintain excitation-contraction coupling junctions in skeletal muscle. J Gen Physiol. 2019 04 01; 151(4):593-605.
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Fill M, Gillespie D. Ryanodine Receptor Open Times Are Determined in the Closed State. Biophys J. 2018 10 02; 115(7):1160-1165.
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Doruelo AL, Haberichter SL, Christopherson PA, Boggio LN, Gupta S, Lentz SR, Shapiro AD, Montgomery RR, Flood VH. Clinical and laboratory phenotype variability in type 2M von Willebrand disease. J Thromb Haemost. 2017 08; 15(8):1559-1566.
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Xu Z, Li W, Han J, Zou C, Huang W, Yu W, Shan X, Lum H, Li X, Liang G. Angiotensin II induces kidney inflammatory injury and fibrosis through binding to myeloid differentiation protein-2 (MD2). Sci Rep. 2017 03 21; 7:44911.
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Qvortrup K, Jensen JF, Sørensen MS, Kouskoumvekaki I, Petersen RK, Taboureau O, Kristiansen K, Nielsen TE. Synthesis and biological evaluation of dihydropyrano-[2,3-c]pyrazoles as a new class of PPAR? partial agonists. PLoS One. 2017; 12(2):e0162642.
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Danilov SM, Lünsdorf H, Akinbi HT, Nesterovitch AB, Epshtein Y, Letsiou E, Kryukova OV, Piegeler T, Golukhova EZ, Schwartz DE, Dull RO, Minshall RD, Kost OA, Garcia JG. Lysozyme and bilirubin bind to ACE and regulate its conformation and shedding. Sci Rep. 2016 10 13; 6:34913.
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Ali YO, Allen HM, Yu L, Li-Kroeger D, Bakhshizadehmahmoudi D, Hatcher A, McCabe C, Xu J, Bjorklund N, Taglialatela G, Bennett DA, De Jager PL, Shulman JM, Bellen HJ, Lu HC. NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies. PLoS Biol. 2016 06; 14(6):e1002472.
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