T-Box Domain Proteins
"T-Box Domain Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins containing a region of conserved sequence, about 200 amino acids long, which encodes a particular sequence specific DNA binding domain (the T-box domain). These proteins are transcription factors that control developmental pathways. The prototype of this family is the mouse Brachyury (or T) gene product.
Descriptor ID |
D020825
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MeSH Number(s) |
D12.776.260.725 D12.776.930.850
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "T-Box Domain Proteins".
Below are MeSH descriptors whose meaning is more specific than "T-Box Domain Proteins".
This graph shows the total number of publications written about "T-Box Domain Proteins" by people in this website by year, and whether "T-Box Domain Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2011 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2017 | 0 | 1 | 1 | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "T-Box Domain Proteins" by people in Profiles.
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Clancy-Thompson E, Chen GZ, LaMarche NM, Ali LR, Jeong HJ, Crowley SJ, Boelaars K, Brenner MB, Lynch L, Dougan SK. Transnuclear mice reveal Peyer's patch iNKT cells that regulate B-cell class switching to IgG1. EMBO J. 2019 07 15; 38(14):e101260.
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Sowell RT, Goldufsky JW, Rogozinska M, Quiles Z, Cao Y, Castillo EF, Finnegan A, Marzo AL. IL-15 Complexes Induce Migration of Resting Memory CD8 T Cells into Mucosal Tissues. J Immunol. 2017 10 01; 199(7):2536-2546.
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Zloza A, Kohlhapp FJ, Lyons GE, Schenkel JM, Moore TV, Lacek AT, O'Sullivan JA, Varanasi V, Williams JW, Jagoda MC, Bellavance EC, Marzo AL, Thomas PG, Zafirova B, Polic B, Al-Harthi L, Sperling AI, Guevara-PatiƱo JA. NKG2D signaling on CD8? T cells represses T-bet and rescues CD4-unhelped CD8? T cell memory recall but not effector responses. Nat Med. 2012 Feb 26; 18(3):422-8.
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Kaplan RC, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Hunt P, Karim R, Kern DM, Hodis HN, Deeks SG. T cell activation and senescence predict subclinical carotid artery disease in HIV-infected women. J Infect Dis. 2011 Feb 15; 203(4):452-63.
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