 Tumor Necrosis Factor-alpha
"Tumor Necrosis Factor-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
| Descriptor ID |
D014409
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| MeSH Number(s) |
D12.644.276.374.500.800 D12.644.276.374.750.626 D12.644.276.972.626 D12.776.124.900 D12.776.395.930 D12.776.467.374.500.800 D12.776.467.374.750.626 D12.776.467.972.626 D23.529.374.500.800 D23.529.374.750.626 D23.529.972.626
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| Concept/Terms |
Tumor Necrosis Factor-alpha- Tumor Necrosis Factor-alpha
- Tumor Necrosis Factor alpha
- Cachectin-Tumor Necrosis Factor
- Cachectin Tumor Necrosis Factor
- TNFalpha
- TNF-alpha
- Tumor Necrosis Factor
- Tumor Necrosis Factor Ligand Superfamily Member 2
- Cachectin
- TNF Superfamily, Member 2
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Below are MeSH descriptors whose meaning is more general than "Tumor Necrosis Factor-alpha".
Below are MeSH descriptors whose meaning is more specific than "Tumor Necrosis Factor-alpha".
This graph shows the total number of publications written about "Tumor Necrosis Factor-alpha" by people in this website by year, and whether "Tumor Necrosis Factor-alpha" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 1 | 1 | 2 | | 1991 | 2 | 0 | 2 | | 1993 | 1 | 0 | 1 | | 1994 | 0 | 3 | 3 | | 1995 | 2 | 0 | 2 | | 1996 | 2 | 1 | 3 | | 1997 | 3 | 6 | 9 | | 1998 | 1 | 4 | 5 | | 1999 | 2 | 9 | 11 | | 2000 | 2 | 3 | 5 | | 2001 | 1 | 2 | 3 | | 2002 | 8 | 7 | 15 | | 2003 | 3 | 4 | 7 | | 2004 | 6 | 5 | 11 | | 2005 | 3 | 8 | 11 | | 2006 | 3 | 4 | 7 | | 2007 | 3 | 5 | 8 | | 2008 | 2 | 7 | 9 | | 2009 | 3 | 3 | 6 | | 2010 | 2 | 5 | 7 | | 2011 | 1 | 4 | 5 | | 2012 | 1 | 4 | 5 | | 2013 | 1 | 8 | 9 | | 2014 | 1 | 4 | 5 | | 2015 | 0 | 2 | 2 | | 2016 | 0 | 2 | 2 | | 2017 | 1 | 4 | 5 | | 2018 | 1 | 3 | 4 | | 2019 | 3 | 0 | 3 | | 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Tumor Necrosis Factor-alpha" by people in Profiles.
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Tollkuci E, Fitzpatrick P, N Seddon A, Myers R, Nathan S, Ustun C. Biosimilar infliximab administration for the management of acute graft-versus-host disease. J Oncol Pharm Pract. 2020 Dec; 26(8):2047-2051.
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Cogswell A, Ferguson N, Barker E. Presence of Inflammatory Group I and III Innate Lymphoid Cells in the Colon of Simian Immunodeficiency Virus-Infected Rhesus Macaques. J Virol. 2020 04 16; 94(9).
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Papagiannopoulos P, Devins K, Tong CCL, Yver C, Patel NN, Kuhar HN, Bosso JV, Kohanski MA, Tajudeen BA, Kuan EC, Batra PS, Cohen NA, Kennedy DW, Palmer JN, Montone K, Adappa ND. Chronic rhinosinusitis precipitated by tumor necrosis factor alpha inhibitors is the phenotype of chronic rhinosinusitis without nasal polyps. Int Forum Allergy Rhinol. 2020 01; 10(1):23-28.
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Cogswell AC, Maski K, Scammell TE, Tucker D, Orban ZS, Koralnik IJ. Children with Narcolepsy type 1 have increased T-cell responses to orexins. Ann Clin Transl Neurol. 2019 12; 6(12):2566-2572.
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Saad RE, Shobar R, Mutlu EA. Collagenous colitis development occurs after long standing mucosal healing in IBD with TNF-a inhibitors, and could be due to exaggerated healing response from excess TNF-a inhibition. Med Hypotheses. 2019 Feb; 123:90-94.
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Bekhbat M, Mehta CC, Kelly SD, Vester A, Ofotokun I, Felger J, Wingood G, Anastos K, Gustafson DR, Kassaye S, Milam J, Aouizerat B, Weber K, Golub ET, Moore MF, Diclemente R, Fischl M, Kempf MC, Maki P, Neigh GN. HIV and symptoms of depression are independently associated with impaired glucocorticoid signaling. Psychoneuroendocrinology. 2018 10; 96:118-125.
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Chen Y, Patel A, Meier PP, Fantuzzi G. Digested Early Preterm Human Milk Suppresses Tumor Necrosis Factor-induced Inflammation and Cytotoxicity in Intestinal Epithelial Cells. J Pediatr Gastroenterol Nutr. 2018 Jun; 66(6):e153-e157.
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Haxaire C, Hakobyan N, Pannellini T, Carballo C, McIlwain D, Mak TW, Rodeo S, Acharya S, Li D, Szymonifka J, Song X, Monette S, Srivastava A, Salmon JE, Blobel CP. Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-a pathway. Blood. 2018 09 06; 132(10):1064-1074.
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Singh V, Rawlinson J, Hallab N. Stainless steel wear debris of a scoliotic growth guidance system has little local and systemic effect in an animal model. J Orthop Res. 2018 07; 36(7):1980-1990.
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French AL, Martin JW, Evans CT, Peters M, Kessaye SG, Nowicki M, Kuniholm M, Golub E, Augenbraun M, Desai SN. Macrophage Activation and the Tumor Necrosis Factor Cascade in Hepatitis C Disease Progression Among HIV-Infected Women Participating in the Women's Interagency HIV Study. . 2017 12 01; 76(4):438-444.
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