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Konstantinos Arfanakis

TitleProfessor
InstitutionRush University, Rush Medical College
DepartmentDiagnostic Radiology and Nuclear Medicine
Address
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    Collapse Biography 
    Collapse awards and honors
    1999Student Stipend, International Society for Magnetic Resonance in Medicine (ISMRM)
    2000Student Stipend, International Society for Magnetic Resonance in Medicine (ISMRM)
    2001Student Stipend, International Society for Magnetic Resonance in Medicine (ISMRM)
    2001Vilas Fellowship
    2002Student Stipend, International Society for Magnetic Resonance in Medicine (ISMRM)
    2002Magna Cum Laude, Radiological Society of North America (RSNA)
    2002Excellence in Design of Education Exhibit, Radiological Society of North America (RSNA)
    2002Figures from journal article AJNR Am. J. Neuroradiol 2002;23:794-802, Cover of that issue of the journal
    2003Journal article Magn. Reson. Med. 2002;47:354-363 was ranked in the Top 10 most assessed papers , Magnetic Resonance in Medicine for the period 2002-2003
    2004Dean's commendation for receiving outstanding teaching evaluations for my BME 535 course
    2005Dean's commendation for receiving outstanding teaching evaluations for my BME 430 course
    2006Dean's commendation for receiving outstanding teaching evaluations for my BME 438 course
    2007Sigma Xi / IIT Award for Excellence in University Research, Junior faculty category
    2008Top 3 for the Bodossaki Foundation Academic Prize , "Theories, Methods, and Techniques, of Biomedical Applications of Informtics and Telecommunications"
    2009Journal article Neuroimage 2009;46:967-980 ranked #11, List of "hottest articles" in Neuromage for April-June (out of 168 papers)
    2010Journal article Am. J. Neuroradiol. 2002:23:794-802 ranked #28, Most Frequently Cited Article in the history of the journal
    2012ISMRM Magna Cum Laude Merit Award, 20th Annual ISMRM international conference
    2012Journal article Nat Genet 2012;44:545-552, received the "Best paper" award, 2012 de Leon Prize in Neuroimaging
    2015Merit Abstract Award, Organization for Human Brain Mapping
    2015ISMRM Summa Cum Laude Merit Award, 23rd Annuial ISMRM international conference
    2017Scientific Sessions, Best Nursing Abstract, American Heart Association
    2017ISMRM Magna Cum Laude Merit Award, 25th Annual ISMRM international conference

    Collapse Overview 
    Collapse overview
    Konstantinos Arfanakis, PhD, is Professor of Biomedical Engineering at the Illinois Institute of Technology, and Leader of the Imaging and Bioengineering Studies at the Rush Alzheimer’s Disease Center. Dr. Arfanakis has expertise in MRI pulse sequence development, image reconstruction, and image processing. His research focuses on multi-parametric MRI in aging and dementia, ex-vivo brain MRI, and brain atlas development.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lamar M, Arfanakis K, Evia A, Makkinejad N, Capuano AW, Kim N, Leurgans SE, Fleischman DA, Duke Han S, Poole V, Barnes LL. Changes in an in-vivo classifier of ARTerioloSclerosis (ARTS) with simultaneous change in cognition for older African Americans. Neurobiol Aging. 2024 Feb; 134:21-27. PMID: 37979249.
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    2. Wang Z, Wang J, Guo J, Dove A, Arfanakis K, Qi X, Bennett DA, Xu W. Association of Motor Function With Cognitive Trajectories and Structural Brain Differences: A Community-Based Cohort Study. Neurology. 2023 10 24; 101(17):e1718-e1728. PMID: 37657942.
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    3. Wuestefeld A, Pichet Binette A, Berron D, Spotorno N, van Westen D, Stomrud E, Mattsson-Carlgren N, Strandberg O, Smith R, Palmqvist S, Glenn T, Moes S, Honer M, Arfanakis K, Barnes LL, Bennett DA, Schneider JA, Wisse LEM, Hansson O. Age-related and amyloid-beta-independent tau deposition and its downstream effects. Brain. 2023 08 01; 146(8):3192-3205. PMID: 37082959.
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    4. Lamar M, Arfanakis K, Yu L, Kapasi A, Duke Han S, Fleischman DA, Bennett DA, Boyle P. The Relationship of MRI-Derived Alzheimer's and Cerebrovascular-Related Signatures With Level of and Change in Health and Financial Literacy. Am J Geriatr Psychiatry. 2023 12; 31(12):1129-1139. PMID: 37541932.
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    5. Nikseresht G, Evia AM, Nag S, Leurgans SE, Capuano AW, Agam G, Barnes LL, Bennett DA, Schneider JA, Arfanakis K. Neuropathologic correlates of cerebral microbleeds in community-based older adults. Neurobiol Aging. 2023 09; 129:89-98. PMID: 37279617.
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    6. Fleischman DA, Arfanakis K, Leurgans SE, Zhang S, Lamar M, Han SD, Poole VN, Kim N, Bennett DA, Barnes LL. Late-life depressive symptoms and white matter structural integrity within older Black adults. Front Aging Neurosci. 2023; 15:1138568. PMID: 37205056.
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    7. Maillard P, Hillmer LJ, Lu H, Arfanakis K, Gold BT, Bauer CE, Kramer JH, Staffaroni AM, Stables L, Wang DJJ, Seshadri S, Satizabal CL, Beiser A, Habes M, Fornage M, Mosley TH, Rosenberg GA, Singh B, Singh H, Schwab K, Helmer KG, Greenberg SM, DeCarli C, Caprihan A. MRI free water as a biomarker for cognitive performance: Validation in the MarkVCID consortium. Alzheimers Dement (Amst). 2022; 14(1):e12362. PMID: 36523847.
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    8. Han SD, Fleischman DA, Yu L, Poole V, Lamar M, Kim N, Leurgans SE, Bennett DA, Arfanakis K, Barnes LL. Cognitive decline and hippocampal functional connectivity within older Black adults. Hum Brain Mapp. 2022 11; 43(16):5044-5052. PMID: 36066181.
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    9. Abdelhak A, Solomon I, Montes SC, Saias A, Cordano C, Asken B, Fonseca C, Oertel FC, Arfanakis K, Staffaroni AM, Kramer JH, Geschwind M, Miller BL, Elahi FM, Green AJ. Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology. Alzheimers Dement (Amst). 2022; 14(1):e12338. PMID: 35814617.
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    10. Tazwar M, Evia AM, Tamhane AA, Ridwan AR, Leurgans SE, Bennett DA, Schneider JA, Arfanakis K. Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is associated with lower R2 relaxation rate: an ex-vivo MRI and pathology investigation. Neurobiol Aging. 2022 09; 117:128-138. PMID: 35728463.
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    11. Maillard P, Lu H, Arfanakis K, Gold BT, Bauer CE, Zachariou V, Stables L, Wang DJJ, Jann K, Seshadri S, Duering M, Hillmer LJ, Rosenberg GA, Snoussi H, Sepehrband F, Habes M, Singh B, Kramer JH, Corriveau RA, Singh H, Schwab K, Helmer KG, Greenberg SM, Caprihan A, DeCarli C, Satizabal CL. Instrumental validation of free water, peak-width of skeletonized mean diffusivity, and white matter hyperintensities: MarkVCID neuroimaging kits. Alzheimers Dement (Amst). 2022; 14(1):e12261. PMID: 35382232.
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    12. Kapasi A, Yu L, Petyuk V, Arfanakis K, Bennett DA, Schneider JA. Association of small vessel disease with tau pathology. Acta Neuropathol. 2022 03; 143(3):349-362. PMID: 35044500.
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    13. Krueger KR, Dhana K, Aggarwal NT, Arfanakis K, Carey VJ, Sacks FM, Barnes LL. Properties of the Cognitive Function Battery for the MIND Diet Intervention to Prevent Alzheimer's Disease. J Int Neuropsychol Soc. 2022 09; 28(8):790-797. PMID: 34612190.
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    14. Boyle PA, Wang T, Yu L, Wilson RS, Dawe R, Arfanakis K, Schneider JA, Bennett DA. To what degree is late life cognitive decline driven by age-related neuropathologies? Brain. 2021 08 17; 144(7):2166-2175. PMID: 33742668.
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    15. Dawe RJ, Yu L, Leurgans SE, James BD, Poole VN, Arfanakis K, Schneider JA, Bennett DA, Buchman AS. Physical activity, brain tissue microstructure, and cognition in older adults. PLoS One. 2021; 16(7):e0253484. PMID: 34232955.
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    16. Kim N, Arfanakis K, Leurgans SE, Yang J, Fleischman DA, Han SD, Aggarwal NT, Lamar M, Yu L, Poole VN, Bennett DA, Barnes LL. Bootstrap approach for meta-synthesis of MRI findings from multiple scanners. J Neurosci Methods. 2021 08 01; 360:109229. PMID: 34052288.
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    17. Ridwan AR, Niaz MR, Wu Y, Qi X, Zhang S, Kontzialis M, Javierre-Petit C, Tazwar M, Bennett DA, Yang Y, Arfanakis K. Development and evaluation of a high performance T1-weighted brain template for use in studies on older adults. Hum Brain Mapp. 2021 04 15; 42(6):1758-1776. PMID: 33449398.
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    18. Yu L, Tasaki S, Schneider JA, Arfanakis K, Duong DM, Wingo AP, Wingo TS, Kearns N, Thatcher GRJ, Seyfried NT, Levey AI, De Jager PL, Bennett DA. Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons. JAMA Psychiatry. 2020 11 01; 77(11):1172-1180. PMID: 32609320.
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    19. Qi X, Arfanakis K. Regionconnect: Rapidly extracting standardized brain connectivity information in voxel-wise neuroimaging studies. Neuroimage. 2021 01 15; 225:117462. PMID: 33075560.
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    20. Lamar M, Arfanakis K, Yu L, Zhang S, Han SD, Fleischman DA, Bennett DA, Boyle PA. White matter correlates of scam susceptibility in community-dwelling older adults. Brain Imaging Behav. 2020 Oct; 14(5):1521-1530. PMID: 30895444.
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    21. Javierre-Petit C, Schneider JA, Kapasi A, Makkinejad N, Tamhane AA, Leurgans SE, Mehta RI, Barnes LL, Bennett DA, Arfanakis K. Neuropathologic and Cognitive Correlates of Enlarged Perivascular Spaces in a Community-Based Cohort of Older Adults. Stroke. 2020 09; 51(9):2825-2833. PMID: 32757750.
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    22. Arfanakis K, Evia AM, Leurgans SE, Cardoso LFC, Kulkarni A, Alqam N, Lopes LF, Vieira D, Bennett DA, Schneider JA. Neuropathologic Correlates of White Matter Hyperintensities in a Community-Based Cohort of Older Adults. J Alzheimers Dis. 2020; 73(1):333-345. PMID: 31771057.
      Citations:    
    23. Dawe RJ, Yu L, Arfanakis K, Schneider JA, Bennett DA, Boyle PA. Late-life cognitive decline is associated with hippocampal volume, above and beyond its associations with traditional neuropathologic indices. Alzheimers Dement. 2020 01; 16(1):209-218. PMID: 31914231.
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    24. van der Lee SJ, Knol MJ, Chauhan G, Satizabal CL, Smith AV, Hofer E, Bis JC, Hibar DP, Hilal S, van den Akker EB, Arfanakis K, Bernard M, Yanek LR, Amin N, Crivello F, Cheung JW, Harris TB, Saba Y, Lopez OL, Li S, van der Grond J, Yu L, Paus T, Roshchupkin GV, Amouyel P, Jahanshad N, Taylor KD, Yang Q, Mathias RA, Boehringer S, Mazoyer B, Rice K, Cheng CY, Maillard P, van Heemst D, Wong TY, Niessen WJ, Beiser AS, Beekman M, Zhao W, Nyquist PA, Chen C, Launer LJ, Psaty BM, Ikram MK, Vernooij MW, Schmidt H, Pausova Z, Becker DM, De Jager PL, Thompson PM, van Duijn CM, Bennett DA, Slagboom PE, Schmidt R, Longstreth WT, Ikram MA, Seshadri S, Debette S, Gudnason V, Adams HHH, DeCarli C. A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. Commun Biol. 2019; 2:285. PMID: 31396565.
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    25. Gaiteri C, Dawe R, Mostafavi S, Blizinsky KD, Tasaki S, Komashko V, Yu L, Wang Y, Schneider JA, Arfanakis K, De Jager PL, Bennett DA. Gene expression and DNA methylation are extensively coordinated with MRI-based brain microstructural characteristics. Brain Imaging Behav. 2019 Aug; 13(4):963-972. PMID: 29934819.
      Citations:    
    26. Bronas UG, Steffen A, Dion C, Boots EA, Arfanakis K, Marquez DX, Lamar M. Sedentary Time and White Matter Hyperintensity Volume in Older Adults. Med Sci Sports Exerc. 2019 08; 51(8):1613-1618. PMID: 30817720.
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    27. Kim N, Yu L, Dawe R, Petyuk VA, Gaiteri C, De Jager PL, Schneider JA, Arfanakis K, Bennett DA. Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline. Neurobiol Aging. 2019 12; 84:17-25. PMID: 31479860.
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    28. Arvanitakis Z, Capuano AW, Brey R, Fleischman DA, Arfanakis K, Buchman AS, Schneider JA, Levine SR, Bennett DA. Antiphospholipid Antibodies: Cognitive and Motor Decline, Neuroimaging and Neuropathology. Neuroepidemiology. 2019; 53(1-2):100-107. PMID: 31067547.
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    29. Vojinovic D, Adams HH, Jian X, Yang Q, Smith AV, Bis JC, Teumer A, Scholz M, Armstrong NJ, Hofer E, Saba Y, Luciano M, Bernard M, Trompet S, Yang J, Gillespie NA, van der Lee SJ, Neumann A, Ahmad S, Andreassen OA, Ames D, Amin N, Arfanakis K, Bastin ME, Becker DM, Beiser AS, Beyer F, Brodaty H, Bryan RN, B?low R, Dale AM, De Jager PL, Deary IJ, DeCarli C, Fleischman DA, Gottesman RF, van der Grond J, Gudnason V, Harris TB, Homuth G, Knopman DS, Kwok JB, Lewis CE, Li S, Loeffler M, Lopez OL, Maillard P, El Marroun H, Mather KA, Mosley TH, Muetzel RL, Nauck M, Nyquist PA, Panizzon MS, Pausova Z, Psaty BM, Rice K, Rotter JI, Royle N, Satizabal CL, Schmidt R, Schofield PR, Schreiner PJ, Sidney S, Stott DJ, Thalamuthu A, Uitterlinden AG, Vald?s Hern?ndez MC, Vernooij MW, Wen W, White T, Witte AV, Wittfeld K, Wright MJ, Yanek LR, Tiemeier H, Kremen WS, Bennett DA, Jukema JW, Paus T, Wardlaw JM, Schmidt H, Sachdev PS, Villringer A, Grabe HJ, Longstreth WT, van Duijn CM, Launer LJ, Seshadri S, Ikram MA, Fornage M. Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. Nat Commun. 2018 09 26; 9(1):3945. PMID: 30258056.
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    30. Han SD, Arfanakis K, Fleischman DA, Yu L, Bennett DA, Boyle PA. White matter correlates of temporal discounting in older adults. Brain Struct Funct. 2018 Nov; 223(8):3653-3663. PMID: 29992469.
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    31. Fleischman DA, Arfanakis K, Leurgans S, Keating SM, Lamar M, Bennett DA, Adeyemi OM, Barnes LL. Neopterin is associated with hippocampal subfield volumes and cognition in HIV. Neurol Neuroimmunol Neuroinflamm. 2018 Jul; 5(4):e467. PMID: 29904644.
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    32. Dawe RJ, Yu L, Schneider JA, Arfanakis K, Bennett DA, Boyle PA. Postmortem brain MRI is related to cognitive decline, independent of cerebral vessel disease in older adults. Neurobiol Aging. 2018 09; 69:177-184. PMID: 29908416.
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    33. Zhang S, Arfanakis K. Evaluation of standardized and study-specific diffusion tensor imaging templates of the adult human brain: Template characteristics, spatial normalization accuracy, and detection of small inter-group FA differences. Neuroimage. 2018 05 15; 172:40-50. PMID: 29414497.
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    34. Yu L, Dawe RJ, Boyle PA, Gaiteri C, Yang J, Buchman AS, Schneider JA, Arfanakis K, De Jager PL, Bennett DA. Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline. JAMA Neurol. 2017 12 01; 74(12):1473-1480. PMID: 29084334.
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    35. White CC, Yang HS, Yu L, Chibnik LB, Dawe RJ, Yang J, Klein HU, Felsky D, Ramos-Miguel A, Arfanakis K, Honer WG, Sperling RA, Schneider JA, Bennett DA, De Jager PL. Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data. PLoS Med. 2017 04; 14(4):e1002287. PMID: 28441426.
      Citations:    
    36. Hibar DP, Adams HHH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivi?res S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beecham AH, Beiser A, Bernard M, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chen Q, Ching CRK, Chouraki V, Cuellar-Partida G, Crivello F, Den Braber A, Doan NT, Ehrlich S, Giddaluru S, Goldman AL, Gottesman RF, Grimm O, Griswold ME, Guadalupe T, Gutman BA, Hass J, Haukvik UK, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, J?rgensen KN, Karbalai N, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liewald DCM, Lopez LM, Luciano M, Macare C, Marquand AF, Matarin M, Mather KA, Mattheisen M, McKay DR, Milaneschi Y, Mu?oz Maniega S, Nho K, Nugent AC, Nyquist P, Loohuis LMO, Oosterlaan J, Papmeyer M, Pirpamer L, P?tz B, Ramasamy A, Richards JS, Risacher SL, Roiz-Santia?ez R, Rommelse N, Ropele S, Rose EJ, Royle NA, Rundek T, S?mann PG, Saremi A, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Trompet S, Vaidya D, Van der Grond J, Van der Lee SJ, Van der Meer D, Van Donkelaar MMJ, Van Eijk KR, Van Erp TGM, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Wittfeld K, Woldehawariat G, Wolf C, Wolfers T, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Craen AJM, De Geus EJC, De Jager PL, De Zubicaray GI, Deary IJ, Debette S, DeCarli C, Delanty N, Depondt C, DeStefano A, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Enzinger C, Erk S, Espeseth T, Fedko IO, Fern?ndez G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Fornage M, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, G?ring HHH, Green RC, Gruber O, Gudnason V, Guelfi S, H?berg AK, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Huentelman M, Hulshoff Pol HE, Ikeda M, Jack CR, Jenkinson M, Johnson R, J?nsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lema?tre H, Liu X, Longo DL, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, M?hleisen TW, M?ller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, N?then MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BWJH, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schmidt H, Schofield PR, Sigursson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Toga AW, Traynor BJ, Troncoso J, Tsolaki M, Tzourio C, Uitterlinden AG, Hern?ndez MCV, Van der Brug M, van der Lugt A, van der Wee NJA, Van Haren NEM, van 't Ent D, Van Tol MJ, Vardarajan BN, Vellas B, Veltman DJ, V?lzke H, Walter H, Wardlaw JM, Wassink TH, Weale ME, Weinberger DR, Weiner MW, Wen W, Westman E, White T, Wong TY, Wright CB, Zielke RH, Zonderman AB, Martin NG, Van Duijn CM, Wright MJ, Longstreth WT, Schumann G, Grabe HJ, Franke B, Launer LJ, Medland SE, Seshadri S, et al. Novel genetic loci associated with hippocampal volume. Nat Commun. 2017 01 18; 8:13624. PMID: 28098162.
      Citations:    
    37. . Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline. JAMA Neurol. 2017; 74:1473-1480.
    38. Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Renter?a ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivi?res S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard M, Bis JC, Blanken LM, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chauhan G, Chen Q, Ching CR, Cuellar-Partida G, Braber AD, Doan NT, Ehrlich S, Filippi I, Ge T, Giddaluru S, Goldman AL, Gottesman RF, Greven CU, Grimm O, Griswold ME, Guadalupe T, Hass J, Haukvik UK, Hilal S, Hofer E, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liao J, Liewald DC, Lopez LM, Luciano M, Macare C, Marquand A, Matarin M, Mather KA, Mattheisen M, Mazoyer B, McKay DR, McWhirter R, Milaneschi Y, Mirza-Schreiber N, Muetzel RL, Maniega SM, Nho K, Nugent AC, Loohuis LM, Oosterlaan J, Papmeyer M, Pappa I, Pirpamer L, Pudas S, P?tz B, Rajan KB, Ramasamy A, Richards JS, Risacher SL, Roiz-Santia?ez R, Rommelse N, Rose EJ, Royle NA, Rundek T, S?mann PG, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Thomson R, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Vaidya D, Van der Grond J, Van der Meer D, Van Donkelaar MM, Van Eijk KR, Van Erp TG, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Woldehawariat G, Wolf C, Wolfers T, Xu B, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Aggarwal NT, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Chen C, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Geus EJ, De Jager PL, de Zubicaray GI, Delanty N, Depondt C, DeStefano AL, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Erk S, Espeseth T, Evans DA, Fedko IO, Fern?ndez G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, G?ring HH, Grabe HJ, Green RC, Gruber O, Gudnason V, Guelfi S, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Hulshoff Pol HE, Ikeda M, Ikram MK, Jack CR, Jenkinson M, Johnson R, J?nsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lema?tre H, Liu X, Longo DL, Longstreth WT, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon KL, McMahon FJ, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, M?hleisen TW, M?ller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, N?then MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BW, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schofield PR, Sigurdsson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Srikanth V, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Tiemeier H, Toga AW, Traynor BJ, Troncoso J, Turner JA, Tzourio C, Uitterlinden AG, Hern?ndez MC, Van der Brug M, Van der Lugt A, Van der Wee NJ, Van Duijn CM, Van Haren NE, Van T Ent D, Van Tol MJ, Vardarajan BN, Veltman DJ, Vernooij MW, V?lzke H, Walter H, Wardlaw JM, Wassink TH, Weale ME, Weinberger DR, Weiner MW, Wen W, Westman E, White T, Wong TY, Wright CB, Zielke HR, Zonderman AB, Deary IJ, DeCarli C, Schmidt H, Martin NG, De Craen AJ, et al. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nat Neurosci. 2016 12; 19(12):1569-1582. PMID: 27694991.
      Citations:    
    39. Boyle PA, Yu L, Fleischman DA, Leurgans S, Yang J, Wilson RS, Schneider JA, Arvanitakis Z, Arfanakis K, Bennett DA. White matter hyperintensities, incident mild cognitive impairment, and cognitive decline in old age. Ann Clin Transl Neurol. 2016 10; 3(10):791-800. PMID: 27752514.
      Citations:    
    40. Dawe RJ, Yu L, Leurgans SE, Schneider JA, Buchman AS, Arfanakis K, Bennett DA, Boyle PA. Postmortem MRI: a novel window into the neurobiology of late life cognitive decline. Neurobiol Aging. 2016 09; 45:169-177. PMID: 27459937.
      Citations:    
    41. Arfanakis K, Wilson RS, Barth CM, Capuano AW, Vasireddi A, Zhang S, Fleischman DA, Bennett DA. Cognitive activity, cognitive function, and brain diffusion characteristics in old age. Brain Imaging Behav. 2016 06; 10(2):455-63. PMID: 25982658.
      Citations:    
    42. Han SD, Boyle PA, Arfanakis K, Fleischman D, Yu L, James BD, Bennett DA. Financial literacy is associated with white matter integrity in old age. Neuroimage. 2016 Apr 15; 130:223-229. PMID: 26899784.
      Citations:    
    43. Felsky D, De Jager PL, Schneider JA, Arfanakis K, Fleischman DA, Arvanitakis Z, Honer WG, Pouget JG, Mizrahi R, Pollock BG, Kennedy JL, Bennett DA, Voineskos AN. Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant. J Cereb Blood Flow Metab. 2016 Apr; 36(4):819-30. PMID: 26762507.
      Citations:    
    44. Lim AS, Fleischman DA, Dawe RJ, Yu L, Arfanakis K, Buchman AS, Bennett DA. Regional Neocortical Gray Matter Structure and Sleep Fragmentation in Older Adults. Sleep. 2016 Jan 01; 39(1):227-35. PMID: 26350471.
      Citations:    
    45. Kotrotsou A, Schneider JA, Bennett DA, Leurgans SE, Dawe RJ, Boyle PA, Golak T, Arfanakis K. Neuropathologic correlates of regional brain volumes in a community cohort of older adults. Neurobiol Aging. 2015 Oct; 36(10):2798-805. PMID: 26195068.
      Citations:    
    46. Fleischman DA, Yang J, Arfanakis K, Arvanitakis Z, Leurgans SE, Turner AD, Barnes LL, Bennett DA, Buchman AS. Physical activity, motor function, and white matter hyperintensity burden in healthy older adults. Neurology. 2015 Mar 31; 84(13):1294-300. PMID: 25762710.
      Citations:    
    47. Chauhan G, Adams HHH, Bis JC, Weinstein G, Yu L, T?glhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, Phan TG, Beare RJ, Arfanakis K, Fleischman D, Vernooij MW, Mazoyer B, Schmidt H, Srikanth V, Knopman DS, Jack CR, Amouyel P, Hofman A, DeCarli C, Tzourio C, van Duijn CM, Bennett DA, Schmidt R, Longstreth WT, Mosley TH, Fornage M, Launer LJ, Seshadri S, Ikram MA, Debette S. Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. Neurobiol Aging. 2015 Apr; 36(4):1765.e7-1765.e16. PMID: 25670335.
      Citations:    
    48. Varentsova A, Zhang S, Arfanakis K. Development of a high angular resolution diffusion imaging human brain template. Neuroimage. 2014 May 01; 91:177-86. PMID: 24440528.
      Citations:    
    49. Zhang S, Arfanakis K. White matter segmentation based on a skeletonized atlas: effects on diffusion tensor imaging studies of regions of interest. J Magn Reson Imaging. 2014 Nov; 40(5):1189-98. PMID: 24925050.
      Citations:    
    50. Kotrotsou A, Bennett DA, Schneider JA, Dawe RJ, Golak T, Leurgans SE, Yu L, Arfanakis K. Ex vivo MR volumetry of human brain hemispheres. Magn Reson Med. 2014 Jan; 71(1):364-74. PMID: 23440751.
      Citations:    
    51. . Role of standardized and study-specific human brain diffusion tensor templates in inter-subject spatial normalization. J Magn Reson Imaging. 2013; 37:372-381.
    52. Arvanitakis Z, Brey RL, Rand JH, Schneider JA, Leurgans SE, Yu L, Buchman AS, Arfanakis K, Fleischman DA, Boyle PA, Bennett DA, Levine SR. Antiphospholipid antibodies, brain infarcts, and cognitive and motor decline in aging (ABICMA): design of a community-based, longitudinal, clinical-pathological study. Neuroepidemiology. 2013; 40(2):73-84. PMID: 23095514.
      Citations:    
    53. Han SD, Boyle PA, Arfanakis K, Fleischman DA, Yu L, Edmonds EC, Bennett DA. Neural intrinsic connectivity networks associated with risk aversion in old age. Behav Brain Res. 2012 Feb 01; 227(1):233-40. PMID: 22044475.
      Citations:    
    54. Wang Y, West JD, Flashman LA, Wishart HA, Santulli RB, Rabin LA, Pare N, Arfanakis K, Saykin AJ. Selective changes in white matter integrity in MCI and older adults with cognitive complaints. Biochim Biophys Acta. 2012 Mar; 1822(3):423-30. PMID: 21867750.
      Citations:    
    55. Zhang S, Peng H, Dawe RJ, Arfanakis K. Enhanced ICBM diffusion tensor template of the human brain. Neuroimage. 2011 Jan 15; 54(2):974-84. PMID: 20851772.
      Citations:    
    56. Fleischman DA, Arfanakis K, Kelly JF, Rajendran N, Buchman AS, Morris MC, Barnes LL, Bennett DA. Regional brain cortical thinning and systemic inflammation in older persons without dementia. J Am Geriatr Soc. 2010 Sep; 58(9):1823-5. PMID: 20863359.
      Citations:    
    57. . Clinical MR Neuroimaging, 2nd Edition. Diffusion and perfusion MR imaging in seizure disorders. 2010; 546-556.
    58. Tamhane AA, Arfanakis K. Motion correction in periodically-rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) and turboprop MRI. Magn Reson Med. 2009 Jul; 62(1):174-82. PMID: 19365858.
      Citations:    
    59. Phan KL, Orlichenko A, Boyd E, Angstadt M, Coccaro EF, Liberzon I, Arfanakis K. Preliminary evidence of white matter abnormality in the uncinate fasciculus in generalized social anxiety disorder. Biol Psychiatry. 2009 Oct 01; 66(7):691-4. PMID: 19362707.
      Citations:    
    60. Dawe RJ, Bennett DA, Schneider JA, Vasireddi SK, Arfanakis K. Postmortem MRI of human brain hemispheres: T2 relaxation times during formaldehyde fixation. Magn Reson Med. 2009 Apr; 61(4):810-8. PMID: 19189294.
      Citations:    
    61. . Handbook of Research on Afvanced Techniques in Diagnostic Imaging and Biomedical Applications. Optimal diffusion encoding strategies for fiber mapping n diffusion MRI. 2009; 90-107.
    62. Gui M, Peng H, Carew JD, Lesniak MS, Arfanakis K. A tractography comparison between turboprop and spin-echo echo-planar diffusion tensor imaging. Neuroimage. 2008 Oct 01; 42(4):1451-62. PMID: 18621131.
      Citations:    
    63. Lukic AS, Wernick MN, Yang Y, Hansen LK, Arfanakis K, Strother SC. Effect of spatial alignment transformations in PCA and ICA of functional neuroimages. IEEE Trans Med Imaging. 2007 Aug; 26(8):1058-68. PMID: 17695126.
      Citations:    
    64. . Investigating the Medial Temporal Lobe in Alzheimer's Disease and Mild Cognitive Impairment, with Turboprop Diffusion Tensor Imaging, MRI-Volumetry and T2-relaxometry. Brain Imaging and Behav. 2007; 1:11-21.
    65. Arfanakis K, Gui M, Lazar M. White matter tractography by means of Turboprop diffusion tensor imaging. Ann N Y Acad Sci. 2005 Dec; 1064:78-87. PMID: 16394149.
      Citations:    
    66. . Imaging of the Nervous System: Diagnostic and Therapeutic Applications, Philadelphia, PA. Mapping brain function with functional magnetic resonance imaging. 2005; 89-100.
    67. . Clinical MR Neuroimaging: Diffusion, Perfusion and Spectroscopy. Diffusion and perfusion MR imaging in seizure disorders. 2005; 509-520.
    68. Witwer BP, Moftakhar R, Hasan KM, Deshmukh P, Haughton V, Field A, Arfanakis K, Noyes J, Moritz CH, Meyerand ME, Rowley HA, Alexander AL, Badie B. Diffusion-tensor imaging of white matter tracts in patients with cerebral neoplasm. J Neurosurg. 2002 Sep; 97(3):568-75. PMID: 12296640.
      Citations:    
    69. Laird AR, Rogers BP, Carew JD, Arfanakis K, Moritz CH, Meyerand ME. Characterizing instantaneous phase relationships in whole-brain fMRI activation data. Hum Brain Mapp. 2002 Jun; 16(2):71-80. PMID: 11954057.
      Citations:    
    70. Cordes D, Haughton V, Carew JD, Arfanakis K, Maravilla K. Hierarchical clustering to measure connectivity in fMRI resting-state data. Magn Reson Imaging. 2002 May; 20(4):305-17. PMID: 12165349.
      Citations:    
    71. . Application of image registration to measurement of intervertebral rotation in the lumbar spine. Magn Reson Med. 2002; 48:1072-1075.
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