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Konstantinos Arfanakis

Title
InstitutionRush University, Rush Medical College
DepartmentNeurological Sciences
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    Collapse Biography 
    Collapse awards and honors
    1999Student Stipend, International Society for Magnetic Resonance in Medicine (ISMRM)
    2000Student Stipend, International Society for Magnetic Resonance in Medicine (ISMRM)
    2001Student Stipend, International Society for Magnetic Resonance in Medicine (ISMRM)
    2001Vilas Fellowship
    2002Student Stipend, International Society for Magnetic Resonance in Medicine (ISMRM)
    2002Magna Cum Laude, Radiological Society of North America (RSNA)
    2002Excellence in Design of Education Exhibit, Radiological Society of North America (RSNA)
    2002Figures from journal article AJNR Am. J. Neuroradiol 2002;23:794-802, Cover of that issue of the journal
    2003Journal article Magn. Reson. Med. 2002;47:354-363 was ranked in the Top 10 most assessed papers , Magnetic Resonance in Medicine for the period 2002-2003
    2004Dean's commendation for receiving outstanding teaching evaluations for my BME 535 course
    2005Dean's commendation for receiving outstanding teaching evaluations for my BME 430 course
    2006Dean's commendation for receiving outstanding teaching evaluations for my BME 438 course
    2007Sigma Xi / IIT Award for Excellence in University Research, Junior faculty category
    2008Top 3 for the Bodossaki Foundation Academic Prize , "Theories, Methods, and Techniques, of Biomedical Applications of Informtics and Telecommunications"
    2009Journal article Neuroimage 2009;46:967-980 ranked #11, List of "hottest articles" in Neuromage for April-June (out of 168 papers)
    2010Journal article Am. J. Neuroradiol. 2002:23:794-802 ranked #28, Most Frequently Cited Article in the history of the journal
    2012ISMRM Magna Cum Laude Merit Award, 20th Annual ISMRM international conference
    2012Journal article Nat Genet 2012;44:545-552, received the "Best paper" award, 2012 de Leon Prize in Neuroimaging
    2015Merit Abstract Award, Organization for Human Brain Mapping
    2015ISMRM Summa Cum Laude Merit Award, 23rd Annuial ISMRM international conference

    Collapse Overview 
    Collapse overview
    Konstantinos Arfanakis, PhD, is Professor of Biomedical Engineering at the Illinois Institute of Technology, and Leader of the Imaging and Bioengineering Studies at the Rush Alzheimer’s Disease Center. Dr. Arfanakis has expertise in MRI pulse sequence development, image reconstruction, and image processing. His research focuses on multi-parametric MRI in aging and dementia, ex-vivo brain MRI, and brain atlas development.


    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Halloway S, Arfanakis K, Wilbur J, Schoeny ME, Pressler SJ. Accelerometer Physical Activity is Associated with Greater Gray Matter Volumes in Older Adults without Dementia or Mild Cognitive Impairment. J Gerontol B Psychol Sci Soc Sci. 2018 Feb 08. PMID: 29432610.
      View in: PubMed
    2. Zhang S, Arfanakis K. Evaluation of standardized and study-specific diffusion tensor imaging templates of the adult human brain: Template characteristics, spatial normalization accuracy, and detection of small inter-group FA differences. Neuroimage. 2018 May 15; 172:40-50. PMID: 29414497.
      View in: PubMed
    3. Evia AM, Kotrotsou A, Tamhane AA, Dawe RJ, Kapasi A, Leurgans SE, Schneider JA, Bennett DA, Arfanakis K. Ex-vivo quantitative susceptibility mapping of human brain hemispheres. PLoS One. 2017; 12(12):e0188395. PMID: 29261693.
      View in: PubMed
    4. Yu L, Dawe RJ, Boyle PA, Gaiteri C, Yang J, Buchman AS, Schneider JA, Arfanakis K, De Jager PL, Bennett DA. Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline. JAMA Neurol. 2017 Dec 01; 74(12):1473-1480. PMID: 29084334.
      View in: PubMed
    5. White CC, Yang HS, Yu L, Chibnik LB, Dawe RJ, Yang J, Klein HU, Felsky D, Ramos-Miguel A, Arfanakis K, Honer WG, Sperling RA, Schneider JA, Bennett DA, De Jager PL. Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data. PLoS Med. 2017 Apr; 14(4):e1002287. PMID: 28441426.
      View in: PubMed
    6. Hibar DP, Adams HHH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beecham AH, Beiser A, Bernard M, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chen Q, Ching CRK, Chouraki V, Cuellar-Partida G, Crivello F, Den Braber A, Doan NT, Ehrlich S, Giddaluru S, Goldman AL, Gottesman RF, Grimm O, Griswold ME, Guadalupe T, Gutman BA, Hass J, Haukvik UK, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Jørgensen KN, Karbalai N, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liewald DCM, Lopez LM, Luciano M, Macare C, Marquand AF, Matarin M, Mather KA, Mattheisen M, McKay DR, Milaneschi Y, Muñoz Maniega S, Nho K, Nugent AC, Nyquist P, Loohuis LMO, Oosterlaan J, Papmeyer M, Pirpamer L, Pütz B, Ramasamy A, Richards JS, Risacher SL, Roiz-Santiañez R, Rommelse N, Ropele S, Rose EJ, Royle NA, Rundek T, Sämann PG, Saremi A, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Trompet S, Vaidya D, Van der Grond J, Van der Lee SJ, Van der Meer D, Van Donkelaar MMJ, Van Eijk KR, Van Erp TGM, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Wittfeld K, Woldehawariat G, Wolf C, Wolfers T, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Craen AJM, De Geus EJC, De Jager PL, De Zubicaray GI, Deary IJ, Debette S, DeCarli C, Delanty N, Depondt C, DeStefano A, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Enzinger C, Erk S, Espeseth T, Fedko IO, Fernández G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Fornage M, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, Göring HHH, Green RC, Gruber O, Gudnason V, Guelfi S, Håberg AK, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Huentelman M, Hulshoff Pol HE, Ikeda M, Jack CR, Jenkinson M, Johnson R, Jönsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lemaître H, Liu X, Longo DL, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, Mühleisen TW, Müller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, Nöthen MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BWJH, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schmidt H, Schofield PR, Sigursson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Toga AW, Traynor BJ, Troncoso J, Tsolaki M, Tzourio C, Uitterlinden AG, Hernández MCV, Van der Brug M, van der Lugt A, van der Wee NJA, Van Haren NEM, van 't Ent D, Van Tol MJ, Vardarajan BN, Vellas B, Veltman DJ, Völzke H, Walter H, Wardlaw JM, Wassink TH, Weale ME, Weinberger DR, Weiner MW, Wen W, Westman E, White T, Wong TY, Wright CB, Zielke RH, Zonderman AB, Martin NG, Van Duijn CM, Wright MJ, Longstreth WT, Schumann G, Grabe HJ, Franke B, Launer LJ, Medland SE, Seshadri S, Thompson PM, Ikram MA. Novel genetic loci associated with hippocampal volume. Nat Commun. 2017 Jan 18; 8:13624. PMID: 28098162.
      View in: PubMed
    7. L. Yu, R.J. Dawe, P.A. Boyle, C. Gaiteri, J. Yang, A.S. Buchman, J.A. Schneider, K. Arfanakis, P.L. De Jager, D.A. Bennett. Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline. JAMA Neurol. 2017; 74:1473-1480.
    8. Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard M, Bis JC, Blanken LM, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chauhan G, Chen Q, Ching CR, Cuellar-Partida G, Braber AD, Doan NT, Ehrlich S, Filippi I, Ge T, Giddaluru S, Goldman AL, Gottesman RF, Greven CU, Grimm O, Griswold ME, Guadalupe T, Hass J, Haukvik UK, Hilal S, Hofer E, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liao J, Liewald DC, Lopez LM, Luciano M, Macare C, Marquand A, Matarin M, Mather KA, Mattheisen M, Mazoyer B, McKay DR, McWhirter R, Milaneschi Y, Mirza-Schreiber N, Muetzel RL, Maniega SM, Nho K, Nugent AC, Loohuis LM, Oosterlaan J, Papmeyer M, Pappa I, Pirpamer L, Pudas S, Pütz B, Rajan KB, Ramasamy A, Richards JS, Risacher SL, Roiz-Santiañez R, Rommelse N, Rose EJ, Royle NA, Rundek T, Sämann PG, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Thomson R, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Vaidya D, Van der Grond J, Van der Meer D, Van Donkelaar MM, Van Eijk KR, Van Erp TG, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Woldehawariat G, Wolf C, Wolfers T, Xu B, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Aggarwal NT, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Chen C, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Geus EJ, De Jager PL, de Zubicaray GI, Delanty N, Depondt C, DeStefano AL, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Erk S, Espeseth T, Evans DA, Fedko IO, Fernández G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, Göring HH, Grabe HJ, Green RC, Gruber O, Gudnason V, Guelfi S, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Hulshoff Pol HE, Ikeda M, Ikram MK, Jack CR, Jenkinson M, Johnson R, Jönsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lemaître H, Liu X, Longo DL, Longstreth WT, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon KL, McMahon FJ, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, Mühleisen TW, Müller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, Nöthen MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BW, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schofield PR, Sigurdsson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Srikanth V, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Tiemeier H, Toga AW, Traynor BJ, Troncoso J, Turner JA, Tzourio C, Uitterlinden AG, Hernández MC, Van der Brug M, Van der Lugt A, Van der Wee NJ, Van Duijn CM, Van Haren NE, Van T Ent D, Van Tol MJ, Vardarajan BN, Veltman DJ, Vernooij MW, Völzke H, Walter H, Wardlaw JM, Wassink TH, Weale ME, Weinberger DR, Weiner MW, Wen W, Westman E, White T, Wong TY, Wright CB, Zielke HR, Zonderman AB, Deary IJ, DeCarli C, Schmidt H, Martin NG, De Craen AJ, Wright MJ, Launer LJ, Schumann G, Fornage M, Franke B, Debette S, Medland SE, Ikram MA, Thompson PM. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nat Neurosci. 2016 12; 19(12):1569-1582. PMID: 27694991.
      View in: PubMed
    9. Yu L, Dawe RJ, Buchman AS, Boyle PA, Schneider JA, Arfanakis K, Bennett DA. Ex vivo MRI transverse relaxation in community based older persons with and without Alzheimer's dementia. Behav Brain Res. 2017 03 30; 322(Pt B):233-240. PMID: 27596378.
      View in: PubMed
    10. Boyle PA, Yu L, Fleischman DA, Leurgans S, Yang J, Wilson RS, Schneider JA, Arvanitakis Z, Arfanakis K, Bennett DA. White matter hyperintensities, incident mild cognitive impairment, and cognitive decline in old age. Ann Clin Transl Neurol. 2016 Oct; 3(10):791-800. PMID: 27752514.
      View in: PubMed
    11. Halloway S, Wilbur J, Schoeny ME, Arfanakis K. Effects of Endurance-Focused Physical Activity Interventions on Brain Health: A Systematic Review. Biol Res Nurs. 2016 Jul 29. PMID: 27474154.
      View in: PubMed
    12. Dawe RJ, Yu L, Leurgans SE, Schneider JA, Buchman AS, Arfanakis K, Bennett DA, Boyle PA. Postmortem MRI: a novel window into the neurobiology of late life cognitive decline. Neurobiol Aging. 2016 09; 45:169-177. PMID: 27459937; PMCID: PMC5003419 [Available on 09/01/17].
    13. Duke Han S, Boyle PA, Yu L, Arfanakis K, James BD, Fleischman DA, Bennett DA. Grey matter correlates of susceptibility to scams in community-dwelling older adults. Brain Imaging Behav. 2016 06; 10(2):524-32. PMID: 26100658.
      View in: PubMed
    14. Arfanakis K, Wilson RS, Barth CM, Capuano AW, Vasireddi A, Zhang S, Fleischman DA, Bennett DA. Cognitive activity, cognitive function, and brain diffusion characteristics in old age. Brain Imaging Behav. 2016 06; 10(2):455-63. PMID: 25982658.
      View in: PubMed
    15. Lee R, Arfanakis K, Evia AM, Fanning J, Keedy S, Coccaro EF. White Matter Integrity Reductions in Intermittent Explosive Disorder. Neuropsychopharmacology. 2016 10; 41(11):2697-703. PMID: 27206265; PMCID: PMC5026737 [Available on 10/01/17].
    16. Han SD, Boyle PA, Arfanakis K, Fleischman D, Yu L, James BD, Bennett DA. Financial literacy is associated with white matter integrity in old age. Neuroimage. 2016 Apr 15; 130:223-229. PMID: 26899784; PMCID: PMC4808430 [Available on 04/15/17].
    17. Felsky D, De Jager PL, Schneider JA, Arfanakis K, Fleischman DA, Arvanitakis Z, Honer WG, Pouget JG, Mizrahi R, Pollock BG, Kennedy JL, Bennett DA, Voineskos AN. Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant. J Cereb Blood Flow Metab. 2016 Apr; 36(4):819-30. PMID: 26762507; PMCID: PMC4821029 [Available on 04/01/17].
    18. Lim AS, Fleischman DA, Dawe RJ, Yu L, Arfanakis K, Buchman AS, Bennett DA. Regional Neocortical Gray Matter Structure and Sleep Fragmentation in Older Adults. Sleep. 2016 Jan 01; 39(1):227-35. PMID: 26350471; PMCID: PMC4678338.
    19. Kotrotsou A, Schneider JA, Bennett DA, Leurgans SE, Dawe RJ, Boyle PA, Golak T, Arfanakis K. Neuropathologic correlates of regional brain volumes in a community cohort of older adults. Neurobiol Aging. 2015 Oct; 36(10):2798-805. PMID: 26195068; PMCID: PMC4562889 [Available on 10/01/16].
    20. Arvanitakis Z, Fleischman DA, Arfanakis K, Leurgans SE, Barnes LL, Bennett DA. Association of white matter hyperintensities and gray matter volume with cognition in older individuals without cognitive impairment. Brain Struct Funct. 2016 05; 221(4):2135-46. PMID: 25833685; PMCID: PMC4592368.
    21. Fleischman DA, Yang J, Arfanakis K, Arvanitakis Z, Leurgans SE, Turner AD, Barnes LL, Bennett DA, Buchman AS. Physical activity, motor function, and white matter hyperintensity burden in healthy older adults. Neurology. 2015 Mar 31; 84(13):1294-300. PMID: 25762710; PMCID: PMC4388751.
    22. Yokoyama JS, Sturm VE, Bonham LW, Klein E, Arfanakis K, Yu L, Coppola G, Kramer JH, Bennett DA, Miller BL, Dubal DB. Variation in longevity gene KLOTHO is associated with greater cortical volumes. Ann Clin Transl Neurol. 2015 Mar; 2(3):215-30. PMID: 25815349; PMCID: PMC4369272.
    23. Chauhan G, Adams HHH, Bis JC, Weinstein G, Yu L, Töglhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, Phan TG, Beare RJ, Arfanakis K, Fleischman D, Vernooij MW, Mazoyer B, Schmidt H, Srikanth V, Knopman DS, Jack CR, Amouyel P, Hofman A, DeCarli C, Tzourio C, van Duijn CM, Bennett DA, Schmidt R, Longstreth WT, Mosley TH, Fornage M, Launer LJ, Seshadri S, Ikram MA, Debette S. Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. Neurobiol Aging. 2015 Apr; 36(4):1765.e7-1765.e16. PMID: 25670335.
      View in: PubMed
    24. Han SD, Boyle PA, Yu L, Fleischman DA, Arfanakis K, Leurgans S, Bennett DA. Financial literacy is associated with medial brain region functional connectivity in old age. Arch Gerontol Geriatr. 2014 Sep-Oct; 59(2):429-38. PMID: 24893911; PMCID: PMC4130771.
    25. Dawe RJ, Bennett DA, Schneider JA, Leurgans SE, Kotrotsou A, Boyle PA, Arfanakis K. Ex vivo T2 relaxation: associations with age-related neuropathology and cognition. Neurobiol Aging. 2014 Jul; 35(7):1549-61. PMID: 24582637; PMCID: PMC3989898.
    26. Varentsova A, Zhang S, Arfanakis K. Development of a high angular resolution diffusion imaging human brain template. Neuroimage. 2014 May 01; 91:177-86. PMID: 24440528; PMCID: PMC3965645.
    27. Zhang S, Arfanakis K. White matter segmentation based on a skeletonized atlas: effects on diffusion tensor imaging studies of regions of interest. J Magn Reson Imaging. 2014 Nov; 40(5):1189-98. PMID: 24925050.
      View in: PubMed
    28. Han SD, Boyle PA, Yu L, Fleischman DA, Arfanakis K, Bennett DA. Ventromedial PFC, parahippocampal, and cerebellar connectivity are associated with temporal discounting in old age. Exp Gerontol. 2013 Dec; 48(12):1489-98. PMID: 24135750; PMCID: PMC3855854.
    29. Arfanakis K, Fleischman DA, Grisot G, Barth CM, Varentsova A, Morris MC, Barnes LL, Bennett DA. Systemic inflammation in non-demented elderly human subjects: brain microstructure and cognition. PLoS One. 2013; 8(8):e73107. PMID: 23991174; PMCID: PMC3753267.
    30. Fleischman DA, Leurgans S, Arfanakis K, Arvanitakis Z, Barnes LL, Boyle PA, Han SD, Bennett DA. Gray-matter macrostructure in cognitively healthy older persons: associations with age and cognition. Brain Struct Funct. 2014 Nov; 219(6):2029-49. PMID: 23955313; PMCID: PMC3926914.
    31. Fleischman DA, Yu L, Arfanakis K, Han SD, Barnes LL, Arvanitakis Z, Boyle PA, Bennett DA. Faster cognitive decline in the years prior to MR imaging is associated with smaller hippocampal volumes in cognitively healthy older persons. Front Aging Neurosci. 2013; 5:21. PMID: 23760360; PMCID: PMC3672675.
    32. Kotrotsou A, Bennett DA, Schneider JA, Dawe RJ, Golak T, Leurgans SE, Yu L, Arfanakis K. Ex vivo MR volumetry of human brain hemispheres. Magn Reson Med. 2014 Jan; 71(1):364-74. PMID: 23440751; PMCID: PMC3664651.
    33. S. Zhang, K. Arfanakis. Role of standardized and study-specific human brain diffusion tensor templates in inter-subject spatial normalization. J Magn Reson Imaging. 2013; 37:372-381.
    34. Duke Han S, Buchman AS, Arfanakis K, Fleischman DA, Bennett DA. Functional connectivity networks associated with chronic musculoskeletal pain in old age. Int J Geriatr Psychiatry. 2013 Aug; 28(8):858-67. PMID: 23124844; PMCID: PMC3594549.
    35. Arvanitakis Z, Brey RL, Rand JH, Schneider JA, Leurgans SE, Yu L, Buchman AS, Arfanakis K, Fleischman DA, Boyle PA, Bennett DA, Levine SR. Antiphospholipid antibodies, brain infarcts, and cognitive and motor decline in aging (ABICMA): design of a community-based, longitudinal, clinical-pathological study. Neuroepidemiology. 2013; 40(2):73-84. PMID: 23095514; PMCID: PMC3638838.
    36. Zhang S, Arfanakis K. Role of standardized and study-specific human brain diffusion tensor templates in inter-subject spatial normalization. J Magn Reson Imaging. 2013 Feb; 37(2):372-81. PMID: 23034880; PMCID: PMC3538117.
    37. Tamhane AA, Arfanakis K, Anastasio M, Guo X, Vannier M, Gao JH. Rapid PROPELLER-MRI: a combination of iterative reconstruction and under-sampling. J Magn Reson Imaging. 2012 Nov; 36(5):1241-7. PMID: 22689510.
      View in: PubMed
    38. Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012 Apr 15; 44(5):545-51. PMID: 22504421.
      View in: PubMed
    39. Han SD, Boyle PA, Arfanakis K, Fleischman DA, Yu L, Edmonds EC, Bennett DA. Neural intrinsic connectivity networks associated with risk aversion in old age. Behav Brain Res. 2012 Feb 01; 227(1):233-40. PMID: 22044475; PMCID: PMC3242855.
    40. Han SD, Arfanakis K, Fleischman DA, Leurgans SE, Tuminello ER, Edmonds EC, Bennett DA. Functional connectivity variations in mild cognitive impairment: associations with cognitive function. J Int Neuropsychol Soc. 2012 Jan; 18(1):39-48. PMID: 22005016; PMCID: PMC3368801.
    41. Dawe RJ, Bennett DA, Schneider JA, Arfanakis K. Neuropathologic correlates of hippocampal atrophy in the elderly: a clinical, pathologic, postmortem MRI study. PLoS One. 2011; 6(10):e26286. PMID: 22043314.
      View in: PubMed
    42. Wang Y, West JD, Flashman LA, Wishart HA, Santulli RB, Rabin LA, Pare N, Arfanakis K, Saykin AJ. Selective changes in white matter integrity in MCI and older adults with cognitive complaints. Biochim Biophys Acta. 2012 Mar; 1822(3):423-30. PMID: 21867750; PMCID: PMC3235544.
    43. Zhang S, Peng H, Dawe RJ, Arfanakis K. Enhanced ICBM diffusion tensor template of the human brain. Neuroimage. 2011 Jan 15; 54(2):974-84. PMID: 20851772; PMCID: PMC2997145.
    44. Fleischman DA, Arfanakis K, Kelly JF, Rajendran N, Buchman AS, Morris MC, Barnes LL, Bennett DA. Regional brain cortical thinning and systemic inflammation in older persons without dementia. J Am Geriatr Soc. 2010 Sep; 58(9):1823-5. PMID: 20863359; PMCID: PMC2945260.
    45. Tamhane AA, Anastasio MA, Gui M, Arfanakis K. Iterative image reconstruction for PROPELLER-MRI using the nonuniform fast fourier transform. J Magn Reson Imaging. 2010 Jul; 32(1):211-7. PMID: 20578028; PMCID: PMC3653304.
    46. K. Arfanakis, P. Hermann. Clinical MR Neuroimaging, 2nd Edition. Diffusion and perfusion MR imaging in seizure disorders. 2010; 546-556.
    47. Tamhane AA, Arfanakis K. Motion correction in periodically-rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) and turboprop MRI. Magn Reson Med. 2009 Jul; 62(1):174-82. PMID: 19365858; PMCID: PMC2731563.
    48. Phan KL, Orlichenko A, Boyd E, Angstadt M, Coccaro EF, Liberzon I, Arfanakis K. Preliminary evidence of white matter abnormality in the uncinate fasciculus in generalized social anxiety disorder. Biol Psychiatry. 2009 Oct 01; 66(7):691-4. PMID: 19362707; PMCID: PMC2743779.
    49. Dawe RJ, Bennett DA, Schneider JA, Vasireddi SK, Arfanakis K. Postmortem MRI of human brain hemispheres: T2 relaxation times during formaldehyde fixation. Magn Reson Med. 2009 Apr; 61(4):810-8. PMID: 19189294; PMCID: PMC2713761.
    50. Peng H, Orlichenko A, Dawe RJ, Agam G, Zhang S, Arfanakis K. Development of a human brain diffusion tensor template. Neuroimage. 2009 Jul 15; 46(4):967-80. PMID: 19341801; PMCID: PMC2693098.
    51. D.C. Karampinos, R.J. Dawe, K. Arfanakis, J.G. Georgiadis. Handbook of Research on Afvanced Techniques in Diagnostic Imaging and Biomedical Applications. Optimal diffusion encoding strategies for fiber mapping n diffusion MRI. 2009; 90-107.
    52. Gui M, Peng H, Carew JD, Lesniak MS, Arfanakis K. A tractography comparison between turboprop and spin-echo echo-planar diffusion tensor imaging. Neuroimage. 2008 Oct 01; 42(4):1451-62. PMID: 18621131; PMCID: PMC2610410.
    53. Gui M, Tamhane AA, Arfanakis K. Contribution of cardiac-induced brain pulsation to the noise of the diffusion tensor in Turboprop diffusion tensor imaging (DTI). J Magn Reson Imaging. 2008 May; 27(5):1164-8. PMID: 18425837.
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    54. Lukic AS, Wernick MN, Yang Y, Hansen LK, Arfanakis K, Strother SC. Effect of spatial alignment transformations in PCA and ICA of functional neuroimages. IEEE Trans Med Imaging. 2007 Aug; 26(8):1058-68. PMID: 17695126.
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    55. K. Arfanakis, M. Gui, A.A. Tamhane, J.D. Carew. Investigating the Medial Temporal Lobe in Alzheimer's Disease and Mild Cognitive Impairment, with Turboprop Diffusion Tensor Imaging, MRI-Volumetry and T2-relaxometry. Brain Imaging and Behav. 2007; 1:11-21.
    56. Peng H, Arfanakis K. Diffusion tensor encoding schemes optimized for white matter fibers with selected orientations. Magn Reson Imaging. 2007 Feb; 25(2):147-53. PMID: 17275608.
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    57. Arfanakis K, Gui M, Lazar M. Optimization of white matter tractography for pre-surgical planning and image-guided surgery. Oncol Rep. 2006; 15 Spec no.:1061-4. PMID: 16525701.
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    58. Arfanakis K, Gui M, Lazar M. White matter tractography by means of Turboprop diffusion tensor imaging. Ann N Y Acad Sci. 2005 Dec; 1064:78-87. PMID: 16394149.
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    59. Arfanakis K, Tamhane AA, Pipe JG, Anastasio MA. k-space undersampling in PROPELLER imaging. Magn Reson Med. 2005 Mar; 53(3):675-83. PMID: 15723398.
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    60. V.M. Haughton, C. Moritz, M.E. Meyerand, K. Arfanakis, D. Cordes. Imaging of the Nervous System: Diagnostic and Therapeutic Applications, Philadelphia, PA. Mapping brain function with functional magnetic resonance imaging. 2005; 89-100.
    61. K. Arfanakis, B.P. Hermann. Clinical MR Neuroimaging: Diffusion, Perfusion and Spectroscopy. Diffusion and perfusion MR imaging in seizure disorders. 2005; 509-520.
    62. Hurley RA, McGowan JC, Arfanakis K, Taber KH. Traumatic axonal injury: novel insights into evolution and identification. J Neuropsychiatry Clin Neurosci. 2004; 16(1):1-7. PMID: 14990753.
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    63. Field AS, Hasan K, Jellison BJ, Arfanakis K, Alexander AL. Diffusion tensor imaging in an infant with traumatic brain swelling. AJNR Am J Neuroradiol. 2003 Aug; 24(7):1461-4. PMID: 12917147.
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    64. Lazar M, Weinstein DM, Tsuruda JS, Hasan KM, Arfanakis K, Meyerand ME, Badie B, Rowley HA, Haughton V, Field A, Alexander AL. White matter tractography using diffusion tensor deflection. Hum Brain Mapp. 2003 Apr; 18(4):306-21. PMID: 12632468.
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    65. Rogers BP, Haughton VM, Arfanakis K, Meyerand ME. Application of image registration to measurement of intervertebral rotation in the lumbar spine. Magn Reson Med. 2002 Dec; 48(6):1072-5. PMID: 12465120.
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    66. Witwer BP, Moftakhar R, Hasan KM, Deshmukh P, Haughton V, Field A, Arfanakis K, Noyes J, Moritz CH, Meyerand ME, Rowley HA, Alexander AL, Badie B. Diffusion-tensor imaging of white matter tracts in patients with cerebral neoplasm. J Neurosurg. 2002 Sep; 97(3):568-75. PMID: 12296640.
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    67. Arfanakis K, Hermann BP, Rogers BP, Carew JD, Seidenberg M, Meyerand ME. Diffusion tensor MRI in temporal lobe epilepsy. Magn Reson Imaging. 2002 Sep; 20(7):511-9. PMID: 12413596.
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    68. Laird AR, Rogers BP, Carew JD, Arfanakis K, Moritz CH, Meyerand ME. Characterizing instantaneous phase relationships in whole-brain fMRI activation data. Hum Brain Mapp. 2002 Jun; 16(2):71-80. PMID: 11954057.
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    69. Cordes D, Haughton V, Carew JD, Arfanakis K, Maravilla K. Hierarchical clustering to measure connectivity in fMRI resting-state data. Magn Reson Imaging. 2002 May; 20(4):305-17. PMID: 12165349.
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    70. Arfanakis K, Haughton VM, Carew JD, Rogers BP, Dempsey RJ, Meyerand ME. Diffusion tensor MR imaging in diffuse axonal injury. AJNR Am J Neuroradiol. 2002 May; 23(5):794-802. PMID: 12006280.
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    71. Arfanakis K, Cordes D, Haughton VM, Carew JD, Meyerand ME. Independent component analysis applied to diffusion tensor MRI. Magn Reson Med. 2002 Feb; 47(2):354-63. PMID: 11810680.
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    72. B.P. Rogers, V.M. Haughton, K. Arfanakis, M.E., Meyerand. Application of image registration to measurement of intervertebral rotation in the lumbar spine. Magn Reson Med. 2002; 48:1072-1075.
    73. Cordes D, Haughton VM, Arfanakis K, Carew JD, Turski PA, Moritz CH, Quigley MA, Meyerand ME. Frequencies contributing to functional connectivity in the cerebral cortex in "resting-state" data. AJNR Am J Neuroradiol. 2001 Aug; 22(7):1326-33. PMID: 11498421.
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    74. Arfanakis K, Cordes D, Haughton VM, Moritz CH, Quigley MA, Meyerand ME. Combining independent component analysis and correlation analysis to probe interregional connectivity in fMRI task activation datasets. Magn Reson Imaging. 2000 Oct; 18(8):921-30. PMID: 11121694.
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    75. Cordes D, Haughton VM, Arfanakis K, Wendt GJ, Turski PA, Moritz CH, Quigley MA, Meyerand ME. Mapping functionally related regions of brain with functional connectivity MR imaging. AJNR Am J Neuroradiol. 2000 Oct; 21(9):1636-44. PMID: 11039342.
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