Profiles

Keywords
Last Name
Institution

Lei Yu

TitleAssociate Professor
InstitutionRush University, Rush Medical College
DepartmentNeurological Sciences
Address
vCardDownload vCard

    Collapse Biography 
    Collapse awards and honors
    2007R. L. Anderson, Summer Research Conference on Statistics , Southern Regional Council on Statistics and American Statistical Association

    Collapse Overview 
    Collapse overview
    Lei Yu is a statistician with Rush Alzheimer’s Disease Center, and associate professor, neurological sciences with Rush University Medical Center. His current research activities focus on providing statistical advice on design and analysis to RADC investigators, and developing methods and applications tailored to the studies on aging and Alzheimer’s disease.
    Yu received his PhD in statistics from the University of Kentucky. He has a particular interest in longitudinal data analysis and statistical modeling of late life cognitive trajectories. Yu has also been actively involved in projects that leverage multi-level omics data to explore the associations between genetic risk factors and aging-related traits.

    My Scopus ID is 56497341800.
    My NIH COMMONS name is LEIYU123.


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Glover CM, Yu L, Stewart CC, Wilson RS, Bennett DA, Lamar M, Boyle PA. Childhood socioeconomic status interacts with cognitive function to impact scam susceptibility among community-dwelling older adults. Aging Ment Health. 2022 Jun 13; 1-6. PMID: 35696371.
      View in: PubMed
    2. Oveisgharan S, Yu L, Wang T, Schneider JA, Bennett DA, Buchman AS. Neurodegenerative and cerebrovascular brain pathologies are differentially associated with declining grip strength and gait in older adults. J Gerontol A Biol Sci Med Sci. 2022 Jun 08. PMID: 35675284.
      View in: PubMed
    3. Li GM, Chen JR, Zhang HQ, Sun C, Chen GR, Xiong QY, Cao XY, Yu L, Lin ZW, Qin JY, Wu LJ, Li J, Pu L, Peng F, Xie XF, Peng C. Rhein activated Fas-induced apoptosis pathway causing cardiotoxicity in vitro and in vivo. Toxicol Lett. 2022 Jun 15; 363:67-76. PMID: 35589017.
      View in: PubMed
    4. Stewart CC, Yu L, Glover CM, Bennett DA, Wilson RS, Boyle PA. Purpose in Life and Cognition Interact to Impact Healthcare and Financial Decision Making in Old Age. J Appl Gerontol. 2022 May 11; 7334648221095514. PMID: 35543174.
      View in: PubMed
    5. Buchman AS, Yu L, Klein HU, Zammit AR, Oveisgharan S, Grodstein F, Tasaki S, Levey AI, Seyfried NT, Bennett DA. Proteome-wide discovery of cortical proteins that may provide motor resilience to offset the negative effects of pathologies in older adults. J Gerontol A Biol Sci Med Sci. 2022 May 04. PMID: 35512265.
      View in: PubMed
    6. Xu K, Yi P, Liu J, Ren J, Zhang Q, Yu L, Yang Y, Wang Y, Ma L, Zhang Y, Li X. Non-invasive brain stimulation interventions for treating Clinical and Sub-clinical eating disorders: A meta-analysis of randomized controlled trials and nonrandomized studies. Psychiatry Res. 2022 07; 313:114592. PMID: 35526422.
      View in: PubMed
    7. Yu L, Mottola G, Barnes LL, Valdes O, Wilson RS, Bennett DA, Boyle PA. Financial fragility and scam susceptibility in community dwelling older adults. J Elder Abuse Negl. 2022 Mar-May; 34(2):93-108. PMID: 35484831.
      View in: PubMed
    8. Boyle PA, Yu L, Mottola G, Innes K, Bennett DA. Degraded Rationality and Suboptimal Decision-Making in Old Age: A Silent Epidemic With Major Economic and Public Health Implications. Public Policy Aging Rep. 2022; 32(2):45-50. PMID: 35607367.
      View in: PubMed
    9. Li Z, Qi X, Zhang X, Yu L, Gao L, Kong W, Chen W, Dong W, Luo L, Lu D, Zhang L, Ma Y. TRDMT1 exhibited protective effects against LPS-induced inflammation in rats through TLR4-NF-?B/MAPK-TNF-a pathway. Animal Model Exp Med. 2022 04; 5(2):172-182. PMID: 35474613.
      View in: PubMed
    10. Shen W, Han G, Yu L, Yang S, Li X, Zhang W, Pei P. Combined Prussian Blue Nanozyme Carriers Improve Photodynamic Therapy and Effective Interruption of Tumor Metastasis. Int J Nanomedicine. 2022; 17:1397-1408. PMID: 35369032.
      View in: PubMed
    11. Oveisgharan S, Yu L, Barnes LL, Agrawal S, Schneider JA, Bennett DA, Buchman AS. Association of Statins With Cerebral Atherosclerosis and Incident Parkinsonism in Older Adults. Neurology. 2022 05 10; 98(19):e1976-e1984. PMID: 35321928.
      View in: PubMed
    12. Li P, Gao L, Yu L, Zheng X, Ulsa MC, Yang HW, Gaba A, Yaffe K, Bennett DA, Buchman AS, Hu K, Leng Y. Daytime napping and Alzheimer's dementia: A potential bidirectional relationship. Alzheimers Dement. 2022 Mar 17. PMID: 35297533.
      View in: PubMed
    13. Zammit AR, Yu L, Petyuk V, Schneider JA, De Jager PL, Klein HU, Bennett DA, Buchman AS. Cortical Proteins and Individual Differences in Cognitive Resilience in Older Adults. Neurology. 2022 03 29; 98(13):e1304-e1314. PMID: 35241503.
      View in: PubMed
    14. Huang F, Bailey LS, Gao T, Jiang W, Yu L, Bennett DA, Zhao J, Basso KB, Guo Z. Analysis and Comparison of Mouse and Human Brain Gangliosides via Two-Stage Matching of MS/MS Spectra. ACS Omega. 2022 Feb 22; 7(7):6403-6411. PMID: 35224401.
      View in: PubMed
    15. Lamar M, Fleischman DA, Leurgans SE, Aggarwal N, Yu L, Kim N, Poole V, Han SD, Arfanakis K, Barnes LL. Relationship of Blood Pressure and White Matter Hyperintensity Burden With Level of and Change in Cognition in Older Black Adults. Psychosom Med. 2022 05 01; 84(4):437-445. PMID: 35100182.
      View in: PubMed
    16. Li M, Xue SL, Tang X, Xu J, Chen S, Han Y, Qiu H, Miao M, Xu N, Tan J, Kang L, Yu Z, Lou X, Xu Y, Chen J, Yan Z, Feng W, Wu D, Yu L. The differential effects of tumor burdens on predicting the net benefits of ssCART-19 cell treatment on r/r B-ALL patients. Sci Rep. 2022 01 10; 12(1):378. PMID: 35013456.
      View in: PubMed
    17. Liu Y, Hu X, Hu X, Yu L, Ji H, Li W, Cai Y, Cheng G, Jiang Y. T follicular helper cells improve the response of patients with chronic hepatitis B to interferon by promoting HBsAb production. J Gastroenterol. 2022 01; 57(1):30-45. PMID: 34988689.
      View in: PubMed
    18. Yu L, Boyle PA, Wingo AP, Yang J, Wang T, Buchman AS, Wingo TS, Seyfried NT, Levey AI, De Jager PL, Schneider JA, Bennett DA. Neuropathologic Correlates of Human Cortical Proteins in Alzheimer Disease and Related Dementias. Neurology. 2022 03 08; 98(10):e1031-e1039. PMID: 34937778.
      View in: PubMed
    19. Li Z, Xu H, Gong Y, Chen W, Zhan Y, Yu L, Sun Y, Li A, He S, Guan B, Wu Y, Xiong G, Fang D, He Y, Tang Q, Yao L, Hu Z, Mei H, He Z, Cai Z, Guo Y, Li X, Zhou L, Huang W. Patient-Derived Upper Tract Urothelial Carcinoma Organoids as a Platform for Drug Screening. Adv Sci (Weinh). 2022 02; 9(4):e2103999. PMID: 34914855.
      View in: PubMed
    20. Oveisgharan S, Yu L, Poole VN, Evia AM, Barnes LL, Schneider JA, Arfanakis K, Bennett DA, Buchman AS. Association of White Matter Hyperintensities With Pathology and Progression of Parkinsonism in Aging. JAMA Neurol. 2021 12 01; 78(12):1494-1502. PMID: 34724033.
      View in: PubMed
    21. Zhang B, Yu L, Cheng M, Zhang Q, Wu J, Yang J, Liu Q, Lu S, Zhao X, Deng K, Liu Y, Wang J, Zhao P. Hepatitis B virus genotype is an independent prognostic factor of telbivudine and tenofovir treatment in hepatitis B surface antigen-positive pregnant women. Food Sci Nutr. 2022 Jan; 10(1):3-11. PMID: 35035905.
      View in: PubMed
    22. Fleischman DA, Arfanakis K, Leurgans SE, Zhang S, Poole VN, Han SD, Yu L, Lamar M, Kim N, Bennett DA, Barnes LL. Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia. Neurobiol Aging. 2022 03; 111:35-43. PMID: 34963062.
      View in: PubMed
    23. Li Y, Sun Y, Yu L, Chen W, Liu H, Yin L, Guang Y, Yang G, Mo X. Complete genome sequence of a novel mitovirus from binucleate Rhizoctonia AG-K strain FAS2909W. Arch Virol. 2022 Jan; 167(1):271-276. PMID: 34773510.
      View in: PubMed
    24. Cong S, Liu Y, Li Y, Chen Y, Chen R, Zhang B, Yu L, Hu Y, Zhao X, Mu M, Cheng M, Huang Z. MiR-571 affects the development and progression of liver fibrosis by regulating the Notch3 pathway. Sci Rep. 2021 11 08; 11(1):21854. PMID: 34750395.
      View in: PubMed
    25. Lim ASP, Srivastava GP, Yu L, Chibnik LB, Xu J, Buchman AS, Schneider JA, Myers AJ, Bennett DA, De Jager PL. Retraction: 24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex. PLoS Genet. 2021 Nov; 17(11):e1009895. PMID: 34735448.
      View in: PubMed
    26. Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, Whitney K, Dangoor DK, Walsh H, Marcora E, Hefti MM, Casella A, Sissoko CT, Kapoor M, Novikova G, Udine E, Wong G, Tang W, Bhangale T, Hunkapiller J, Ayalon G, Graham RR, Cherry JD, Cortes EP, Borukov VY, McKee AC, Stein TD, Vonsattel JP, Teich AF, Gearing M, Glass J, Troncoso JC, Frosch MP, Hyman BT, Dickson DW, Murray ME, Attems J, Flanagan ME, Mao Q, Mesulam MM, Weintraub S, Woltjer RL, Pham T, Kofler J, Schneider JA, Yu L, Purohit DP, Haroutunian V, Hof PR, Gandy S, Sano M, Beach TG, Poon W, Kawas CH, Corrada MM, Rissman RA, Metcalf J, Shuldberg S, Salehi B, Nelson PT, Trojanowski JQ, Lee EB, Wolk DA, McMillan CT, Keene CD, Latimer CS, Montine TJ, Kovacs GG, Lutz MI, Fischer P, Perrin RJ, Cairns NJ, Franklin EE, Cohen HT, Raj T, Cobos I, Frost B, Goate A, White Iii CL, Crary JF. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathol. 2022 01; 143(1):33-53. PMID: 34719765.
      View in: PubMed
    27. Yu L, Mottola G, Wilson RS, Valdes O, Bennett DA, Boyle PA. Metamemory and financial decision making in older adults without dementia. Neuropsychology. 2022 Jan; 36(1):35-43. PMID: 34726461.
      View in: PubMed
    28. Yu L, Huo Z, Yang J, Palma-Gudiel H, Boyle PA, Schneider JA, Bennett DA, Zhao J. Human Brain and Blood N-Glycome Profiling in Alzheimer's Disease and Alzheimer's Disease-Related Dementias. Front Aging Neurosci. 2021; 13:765259. PMID: 34776937.
      View in: PubMed
    29. Zhao F, Zhao H, Fan J, Wang R, Han Z, Tao Z, Zheng Y, Yan F, Huang Y, Yu L, Zhang X, Qi X, Zhang L, Luo Y, Ma Y. Corrigendum: MiR-29a Knockout Aggravates Neurological Damage by Pre-polarizing M1 Microglia in Experimental Rat Models of Acute Stroke. Front Genet. 2021; 12:738582. PMID: 34764981.
      View in: PubMed
    30. Yu L, Lemay P, Ludlow A, Guyot MC, Jones M, Mohamed FF, Saroya GA, Panaretos C, Schneider E, Wang Y, Myers G, Khoriaty R, Li Q, Franceschi R, Engel JD, Kaartinen V, Rothstein TL, Justice MJ, Kibar Z, Singh SA. A new murine Rpl5 (uL18) mutation provides a unique model of variably penetrant Diamond-Blackfan anemia. Blood Adv. 2021 10 26; 5(20):4167-4178. PMID: 34464976.
      View in: PubMed
    31. Qi X, Chen X, Guo J, Zhang X, Sun H, Wang J, Qian X, Li B, Tan L, Yu L, Chen W, Zhang L, Ma Y, Shen B. Precision modeling of mitochondrial disease in rats via DdCBE-mediated mtDNA editing. Cell Discov. 2021 Oct 19; 7(1):95. PMID: 34663794.
      View in: PubMed
    32. Li L, Cai G, Lu W, Li F, Yu L, Xiao J. The ratio of HDL-C to apoA-I interacts with free triiodothyronine to modulate coronary artery disease risk. BMC Cardiovasc Disord. 2021 10 19; 21(1):504. PMID: 34666674.
      View in: PubMed
    33. Agrawal S, Yu L, Nag S, Arfanakis K, Barnes LL, Bennett DA, Schneider JA. The association of Lewy bodies with limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes and their role in cognition and Alzheimer's dementia in older persons. Acta Neuropathol Commun. 2021 09 25; 9(1):156. PMID: 34563269.
      View in: PubMed
    34. Liu J, Xu N, Wang X, Wang Y, Wu Q, Li X, Pan D, Wang L, Xu Y, Yan J, Li X, Yu L, Yang M. Quantitative radio-thin-layer chromatography and positron emission tomography studies for measuring streptavidin transduced chimeric antigen receptor T cells. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Oct 01; 1182:122944. PMID: 34592686.
      View in: PubMed
    35. Yang F, Duan M, Zheng F, Yu L, Wang Y, Wang G, Lin J, Han S, Gan D, Meng Z, Zhu S. Fas signaling in adipocytes promotes low-grade inflammation and lung metastasis of colorectal cancer through interaction with Bmx. Cancer Lett. 2021 12 01; 522:93-104. PMID: 34536556.
      View in: PubMed
    36. Ma Y, Yu L, Olah M, Smith R, Oatman SR, Allen M, Pishva E, Zhang B, Menon V, Ertekin-Taner N, Lunnon K, Bennett DA, Klein HU, De Jager PL. Epigenomic features related to microglia are associated with attenuated effect of APOE e4 on Alzheimer's disease risk in humans. Alzheimers Dement. 2022 04; 18(4):688-699. PMID: 34482628.
      View in: PubMed
    37. Boyle PA, Wang T, Yu L, Wilson RS, Dawe R, Arfanakis K, Schneider JA, Bennett DA. To what degree is late life cognitive decline driven by age-related neuropathologies? Brain. 2021 08 17; 144(7):2166-2175. PMID: 33742668.
      View in: PubMed
    38. Cao S, Yan W, Yu L, Zhang L, Lay W, Zhou Y. Challenges of THP-AD centrate treatment using partial nitritation-anammox (PN/A) - inhibition, biomass washout, low alkalinity, recalcitrant and more. Water Res. 2021 Sep 15; 203:117555. PMID: 34416648.
      View in: PubMed
    39. Qiu C, Sun Y, Xu Y, Zhang B, Zhang X, Yu L, Su C. Photoredox-Catalyzed Simultaneous Olefin Hydrogenation and Alcohol Oxidation over Crystalline Porous Polymeric Carbon Nitride. ChemSusChem. 2021 Aug 23; 14(16):3344-3350. PMID: 34180144.
      View in: PubMed
    40. Wilson RS, Wang T, Yu L, Grodstein F, Bennett DA, Boyle PA. Cognitive Activity and Onset Age of Incident Alzheimer Disease Dementia. Neurology. 2021 08 31; 97(9):e922-e929. PMID: 34261788.
      View in: PubMed
    41. Han SD, Barnes LL, Leurgans S, Yu L, Stewart CC, Lamar M, Glover CM, Bennett DA, Boyle PA. Susceptibility to Scams in Older Black and White Adults. Front Psychol. 2021; 12:685258. PMID: 34322065.
      View in: PubMed
    42. Dawe RJ, Yu L, Leurgans SE, James BD, Poole VN, Arfanakis K, Schneider JA, Bennett DA, Buchman AS. Physical activity, brain tissue microstructure, and cognition in older adults. PLoS One. 2021; 16(7):e0253484. PMID: 34232955.
      View in: PubMed
    43. Grodstein F, Lemos B, Yu L, Klein HU, Iatrou A, Buchman AS, Shireby GL, Mill J, Schneider JA, De Jager PL, Bennett DA. The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes. Neurobiol Dis. 2021 09; 157:105428. PMID: 34153464.
      View in: PubMed
    44. Yu L, Zhang W, Wang P, Zhang Q, Cong A, Yang X, Sang K. LncRNA SNHG11 aggravates cell proliferation and migration in triple-negative breast cancer via sponging miR-2355-5p and targeting CBX5. Exp Ther Med. 2021 Aug; 22(2):892. PMID: 34257707.
      View in: PubMed
    45. Nag S, Barnes LL, Yu L, Buchman AS, Bennett DA, Schneider JA, Wilson RS. Association of Lewy Bodies With Age-Related Clinical Characteristics in Black and White Decedents. Neurology. 2021 08 24; 97(8):e825-e835. PMID: 34088871.
      View in: PubMed
    46. Li P, Gaba A, Wong PM, Cui L, Yu L, Bennett DA, Buchman AS, Gao L, Hu K. Objective Assessment of Daytime Napping and Incident Heart Failure in 1140 Community-Dwelling Older Adults: A Prospective, Observational Cohort Study. J Am Heart Assoc. 2021 06 15; 10(12):e019037. PMID: 34075783.
      View in: PubMed
    47. Boyle PA, Wang T, Yu L, Wilson RS, Dawe R, Arfanakis K, Schneider JA, Beck T, Rajan KB, Evans D, Bennett DA. The "cognitive clock": A novel indicator of brain health. Alzheimers Dement. 2021 12; 17(12):1923-1937. PMID: 34060702.
      View in: PubMed
    48. Buchman AS, Yu L, Oveisgharan S, Petyuk VA, Tasaki S, Gaiteri C, Wilson RS, Grodstein F, Schneider JA, Klein HU, De Jager PL, Bennett DA. Cortical proteins may provide motor resilience in older adults. Sci Rep. 2021 05 28; 11(1):11311. PMID: 34050212.
      View in: PubMed
    49. Kim N, Arfanakis K, Leurgans SE, Yang J, Fleischman DA, Han SD, Aggarwal NT, Lamar M, Yu L, Poole VN, Bennett DA, Barnes LL. Bootstrap approach for meta-synthesis of MRI findings from multiple scanners. J Neurosci Methods. 2021 08 01; 360:109229. PMID: 34052288.
      View in: PubMed
    50. Boyle PA, Wang T, Yu L, Barnes LL, Wilson RS, Bennett DA. Purpose in Life May Delay Adverse Health Outcomes in Old Age. Am J Geriatr Psychiatry. 2022 Feb; 30(2):174-181. PMID: 34175231.
      View in: PubMed
    51. Weissberger GH, Han SD, Yu L, Barnes LL, Lamar M, Bennett DA, Boyle PA. Impact of Early Life Socioeconomic Status on Decision Making in Older Adults Without Dementia. Arch Gerontol Geriatr. 2021 Jul-Aug; 95:104432. PMID: 34034033.
      View in: PubMed
    52. Sun H, Wang Y, Jing HY, Yang XY, Shi XX, Zhang JH, Yu YX, Gao L, Wang XY, Li WH, Yu L. Chaperonin-Containing TCP1 Subunit 6A Is a Prognostic Potential Biomarker That Correlates With the Presence of Immune Infiltrates in Colorectal Cancer. Front Genet. 2021; 12:629856. PMID: 34017352.
      View in: PubMed
    53. Luo H, Zhai L, Qiu W, Liang H, Yu L, Li Y, Xiong M, Guo J, Tang H. p16 loss facilitate hydroquinone-induced malignant transformation of TK6 cells through promoting cell proliferation and accelerating the cell cycle progression. Environ Toxicol. 2021 Aug; 36(8):1591-1599. PMID: 33932074.
      View in: PubMed
    54. Sommer R, Yu L, Schneider JA, Bennett DA, Buchman AS, Lim ASP. Disrupted Rest-Activity Rhythms and Cerebral Small Vessel Disease Pathology in Older Adults. Stroke. 2021 07; 52(7):2427-2431. PMID: 33902300.
      View in: PubMed
    55. Petyuk VA, Yu L, Olson HM, Yu F, Clair G, Qian WJ, Shulman JM, Bennett DA. Proteomic Profiling of the Substantia Nigra to Identify Determinants of Lewy Body Pathology and Dopaminergic Neuronal Loss. J Proteome Res. 2021 05 07; 20(5):2266-2282. PMID: 33900085.
      View in: PubMed
    56. Yu L, Mottola G, Barnes LL, Han SD, Wilson RS, Bennett DA, Boyle PA. Correlates of Susceptibility to Scams in Community-Dwelling Older Black Adults. Gerontology. 2021; 67(6):729-739. PMID: 33882498.
      View in: PubMed
    57. Oveisgharan S, Yu L, Capuano A, Arvanitakis Z, Barnes LL, Schneider JA, Bennett DA, Buchman AS. Late-Life Vascular Risk Score in Association With Postmortem Cerebrovascular Disease Brain Pathologies. Stroke. 2021 06; 52(6):2060-2067. PMID: 33840227.
      View in: PubMed
    58. Buchman AS, Yu L, Oveisgharan S, Farfel JM, Schneider JA, Bennett DA. Person-Specific Contributions of Brain Pathologies to Progressive Parkinsonism in Older Adults. J Gerontol A Biol Sci Med Sci. 2021 03 31; 76(4):615-621. PMID: 32720690.
      View in: PubMed
    59. Zhao F, Zhao H, Fan J, Wang R, Han Z, Tao Z, Zheng Y, Yan F, Huang Y, Yu L, Zhang X, Qi X, Zhang L, Luo Y, Ma Y. MiR-29a Knockout Aggravates Neurological Damage by Pre-polarizing M1 Microglia in Experimental Rat Models of Acute Stroke. Front Genet. 2021; 12:642079. PMID: 33790947.
      View in: PubMed
    60. Li X, Yu L, Shi X, Rao C, Zhou Y. Capillary isoelectric focusing with UV fluorescence imaging detection enables direct charge heterogeneity characterization of erythropoietin drug products. J Chromatogr A. 2021 Apr 26; 1643:462043. PMID: 33780879.
      View in: PubMed
    61. Cong S, Li Z, Yu L, Liu Y, Hu Y, Bi Y, Cheng M. Integrative proteomic and lipidomic analysis of Kaili Sour Soup-mediated attenuation of high-fat diet-induced nonalcoholic fatty liver disease in a rat model. Nutr Metab (Lond). 2021 Mar 10; 18(1):26. PMID: 33691721.
      View in: PubMed
    62. Ma Y, Lu D, Bao L, Qu Y, Liu J, Qi X, Yu L, Zhang X, Qi F, Lv Q, Liu Y, Shi X, Sun C, Li J, Wang J, Han Y, Gao K, Dong W, Liu N, Gao S, Xue J, Wei Q, Pan S, Gao H, Zhang L, Qin C. SARS-CoV-2 infection aggravates chronic comorbidities of cardiovascular diseases and diabetes in mice. Animal Model Exp Med. 2021 03; 4(1):2-15. PMID: 33738432.
      View in: PubMed
    63. Che P, Yu L, Friedman GK, Wang M, Ke X, Wang H, Zhang W, Nabors B, Ding Q, Han X. Integrin avß3 Engagement Regulates Glucose Metabolism and Migration through Focal Adhesion Kinase (FAK) and Protein Arginine Methyltransferase 5 (PRMT5) in Glioblastoma Cells. Cancers (Basel). 2021 Mar 05; 13(5). PMID: 33807786.
      View in: PubMed
    64. Agrawal S, Yu L, Kapasi A, James BD, Arfanakis K, Barnes LL, Bennett DA, Nag S, Schneider JA. Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change and microvascular pathologies in community-dwelling older persons. Brain Pathol. 2021 05; 31(3):e12939. PMID: 33624322.
      View in: PubMed
    65. Sun Y, Yu L, Liu C, Ye S, Chen W, Li D, Huang W. One-tube SARS-CoV-2 detection platform based on RT-RPA and CRISPR/Cas12a. J Transl Med. 2021 02 16; 19(1):74. PMID: 33593370.
      View in: PubMed
    66. Deters KD, Mormino EC, Yu L, Lutz MW, Bennett DA, Barnes LL. TOMM40-APOE haplotypes are associated with cognitive decline in non-demented Blacks. Alzheimers Dement. 2021 08; 17(8):1287-1296. PMID: 33580752.
      View in: PubMed
    67. Yu L, Mottola G, Bennett DA, Boyle PA. Adverse Impacts of Declining Financial and Health Literacy in Old Age. Am J Geriatr Psychiatry. 2021 11; 29(11):1129-1139. PMID: 33676832.
      View in: PubMed
    68. Yu L, Han S, Lang L, Song H, Zhang C, Dong L, Jia S, Zhang Y, Xiao D, Liu J, Xu Y, Zhang X. Oxocrebanine: A Novel Dual Topoisomerase inhibitor, Suppressed the Proliferation of Breast Cancer Cells MCF-7 by Inducing DNA Damage and Mitotic Arrest. Phytomedicine. 2021 Apr; 84:153504. PMID: 33611211.
      View in: PubMed
    69. Oveisgharan S, Yu L, Bennett DA, Buchman AS. Incident mobility disability, parkinsonism, and mortality in community-dwelling older adults. PLoS One. 2021; 16(2):e0246206. PMID: 33534811.
      View in: PubMed
    70. Yu L, Li Z, Mei H, Li W, Chen D, Liu L, Zhang Z, Sun Y, Song F, Chen W, Huang W. Patient-derived organoids of bladder cancer recapitulate antigen expression profiles and serve as a personal evaluation model for CAR-T cells in vitro. Clin Transl Immunology. 2021; 10(2):e1248. PMID: 33552510.
      View in: PubMed
    71. Walker JM, Richardson TE, Farrell K, Iida MA, Foong C, Shang P, Attems J, Ayalon G, Beach TG, Bigio EH, Budson A, Cairns NJ, Corrada M, Cortes E, Dickson DW, Fischer P, Flanagan ME, Franklin E, Gearing M, Glass J, Hansen LA, Haroutunian V, Hof PR, Honig L, Kawas C, Keene CD, Kofler J, Kovacs GG, Lee EB, Lutz MI, Mao Q, Masliah E, McKee AC, McMillan CT, Mesulam MM, Murray M, Nelson PT, Perrin R, Pham T, Poon W, Purohit DP, Rissman RA, Sakai K, Sano M, Schneider JA, Stein TD, Teich AF, Trojanowski JQ, Troncoso JC, Vonsattel JP, Weintraub S, Wolk DA, Woltjer RL, Yamada M, Yu L, White CL, Crary JF. Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy. J Neuropathol Exp Neurol. 2021 01 20; 80(2):102-111. PMID: 33367843.
      View in: PubMed
    72. Yang M, Sun R, Wang Y, Xu H, Zou B, Yang Y, Cong M, Zheng Y, Yu L, Ma F, Qiu T, Li J. Study Protocol for the Evaluation of Individual Psychological Interventions for Family Caregivers of Advanced Cancer Patients. Front Psychol. 2020; 11:587627. PMID: 33584422.
      View in: PubMed
    73. Liu Y, Fan L, Cheng Z, Yu L, Cong S, Hu Y, Zhu L, Zhang B, Cheng Y, Zhao P, Zhao X, Cheng M. Fecal transplantation alleviates acute liver injury in mice through regulating Treg/Th17 cytokines balance. Sci Rep. 2021 01 15; 11(1):1611. PMID: 33452411.
      View in: PubMed
    74. Yang S, Han G, Chen Q, Yu L, Wang P, Zhang Q, Dong J, Zhang W, Huang J. Au-Pt Nanoparticle Formulation as a Radiosensitizer for Radiotherapy with Dual Effects. Int J Nanomedicine. 2021; 16:239-248. PMID: 33469284.
      View in: PubMed
    75. Grodstein F, Lemos B, Yu L, Iatrou A, De Jager PL, Bennett DA. Characteristics of Epigenetic Clocks Across Blood and Brain Tissue in Older Women and Men. Front Neurosci. 2020; 14:555307. PMID: 33488342.
      View in: PubMed
    76. Xu L, Wu Y, Chen Y, Li R, Wang Z, Li Z, Liu G, Yu L, Shi W, Liang X. Is acute kidney injury age-dependent in older adults: an observational study in two centers from North China. BMC Geriatr. 2021 01 06; 21(1):7. PMID: 33407184.
      View in: PubMed
    77. Zheng WX, Hou GD, Zhang W, Wei D, Gao XL, Chen MH, Huang LG, Yan F, Zhang G, Yu L, Liu F, Zhang B, Yuan JL. Establishment and internal validation of preoperative nomograms for predicting the possibility of testicular salvage in patients with testicular torsion. Asian J Androl. 2021 Jan-Feb; 23(1):97-102. PMID: 32687070.
      View in: PubMed
    78. Kapasi A, Yu L, Stewart C, Schneider JA, Bennett DA, Boyle PA. Association of Amyloid-ß Pathology with Decision Making and Scam Susceptibility. J Alzheimers Dis. 2021; 83(2):879-887. PMID: 34366345.
      View in: PubMed
    79. Wang Y, Yu L, Engel JD, Singh SA. Epigenetic activities in erythroid cell gene regulation. Semin Hematol. 2021 01; 58(1):4-9. PMID: 33509442.
      View in: PubMed
    80. Feng S, Wu J, Qiu WL, Yang L, Deng X, Zhou Y, Chen Y, Li X, Yu L, Li H, Xu ZR, Xiao Y, Ren X, Zhang L, Wang C, Sun Z, Wang J, Ding X, Chen Y, Gadue P, Pan G, Ogawa M, Ogawa S, Na J, Zhang P, Hui L, Yin H, Chen L, Xu CR, Cheng X. Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells. Cell Rep. 2020 12 08; 33(10):108455. PMID: 33296648.
      View in: PubMed
    81. Ma Y, Yu L, Olah M, Smith R, Oatman SR, Allen M, Pishva E, Zhang B, Menon V, Ertekin-Taner N, Lunnon K, Bennett DA, Klein HU, De Jager PL. EPIGENOMIC FEATURES RELATED TO MICROGLIA ARE ASSOCIATED WITH ATTENUATED EFFECT OF APOE e4 ON ALZHEIMER'S DISEASE RISK IN HUMANS. Alzheimers Dement. 2020 12; 16(Suppl 2). PMID: 34393677.
      View in: PubMed
    82. Stewart CC, Yu L, Glover CM, Mottola G, Bennett DA, Wilson RS, Boyle PA. Loneliness Interacts With Cognition in Relation to Healthcare and Financial Decision Making Among Community-Dwelling Older Adults. Gerontologist. 2020 11 23; 60(8):1476-1484. PMID: 32574350.
      View in: PubMed
    83. Li P, Gao L, Gaba A, Yu L, Cui L, Fan W, Lim ASP, Bennett DA, Buchman AS, Hu K. Circadian disturbances in Alzheimer's disease progression: a prospective observational cohort study of community-based older adults. Lancet Healthy Longev. 2020 Dec; 1(3):e96-e105. PMID: 34179863.
      View in: PubMed
    84. Yu L, Tasaki S, Schneider JA, Arfanakis K, Duong DM, Wingo AP, Wingo TS, Kearns N, Thatcher GRJ, Seyfried NT, Levey AI, De Jager PL, Bennett DA. Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons. JAMA Psychiatry. 2020 11 01; 77(11):1172-1180. PMID: 32609320.
      View in: PubMed
    85. Huang W, Yu L, Wen D, Wei D, Sun Y, Zhao H, Ye Y, Chen W, Zhu Y, Wang L, Wang L, Wu W, Zhao Q, Xu Y, Gu D, Nie G, Zhu D, Guo Z, Ma X, Niu L, Huang Y, Liu Y, Peng B, Zhang R, Zhang X, Li D, Liu Y, Yang G, Liu L, Zhou Y, Wang Y, Hou T, Gao Q, Li W, Chen S, Hu X, Han M, Zheng H, Weng J, Cai Z, Zhang X, Song F, Zhao G, Wang J. A CRISPR-Cas12a-based specific enhancer for more sensitive detection of SARS-CoV-2 infection. EBioMedicine. 2020 Nov; 61:103036. PMID: 33045467.
      View in: PubMed
    86. Yu L, Schneider JA, Kapasi A, Bennett DA, Boyle PA. Limbic-predominant Age-related TDP-43 Encephalopathy and Distinct Longitudinal Profiles of Domain-specific Literacy. Alzheimer Dis Assoc Disord. 2020 Oct-Dec; 34(4):299-305. PMID: 32452861.
      View in: PubMed
    87. Oveisgharan S, Wilson RS, Yu L, Schneider JA, Bennett DA. Association of Early-Life Cognitive Enrichment With Alzheimer Disease Pathological Changes and Cognitive Decline. JAMA Neurol. 2020 10 01; 77(10):1217-1224. PMID: 32597941.
      View in: PubMed
    88. Lamar M, Arfanakis K, Yu L, Zhang S, Han SD, Fleischman DA, Bennett DA, Boyle PA. White matter correlates of scam susceptibility in community-dwelling older adults. Brain Imaging Behav. 2020 Oct; 14(5):1521-1530. PMID: 30895444.
      View in: PubMed
    89. Chen Z, Fan Z, Dou X, Zhou Q, Zeng G, Liu L, Chen W, Lan R, Liu W, Ru G, Yu L, He QY, Chen L. Inactivation of tumor suppressor gene Clusterin leads to hyperactivation of TAK1-NF-?B signaling axis in lung cancer cells and denotes a therapeutic opportunity. Theranostics. 2020; 10(25):11520-11534. PMID: 33052230.
      View in: PubMed
    90. Wang XY, Wang Y, Wu Q, Liu JJ, Liu Y, Pan DH, Qi W, Wang LZ, Yan JJ, Xu YP, Wang GJ, Miao LY, Yu L, Yang M. Feasibility study of 68Ga-labeled CAR T cells for in vivo tracking using micro-positron emission tomography imaging. Acta Pharmacol Sin. 2021 May; 42(5):824-831. PMID: 32901086.
      View in: PubMed
    91. Jurkiewicz M, Moser D, Koller A, Yu L, Chen EI, Bennett DA, Canli T. Integration of postmortem amygdala expression profiling, GWAS, and functional cell culture assays: neuroticism-associated synaptic vesicle glycoprotein 2A (SV2A) gene is regulated by miR-133a and miR-218. Transl Psychiatry. 2020 08 24; 10(1):297. PMID: 32839459.
      View in: PubMed
    92. Cong M, Zhu W, Wang C, Fu Z, Song C, Dai Z, Yao K, Guo Z, Lin Y, Shi Y, Hu W, Ba Y, Li S, Li Z, Wang K, Wu J, He Y, Yang J, Xie C, Song X, Chen G, Ma W, Luo S, Chen Z, Ma H, Zhou C, Wang W, Luo Q, Shi Y, Qi Y, Jiang H, Guan W, Chen J, Chen J, Fang Y, Zhou L, Feng Y, Tan R, Li T, Ou J, Zhao Q, Wu J, Deng L, Lin X, Yang L, Xu H, Li W, Yu L, Shi H. Nutritional status and survival of 8247 cancer patients with or without diabetes mellitus-results from a prospective cohort study. Cancer Med. 2020 10; 9(20):7428-7439. PMID: 32813914.
      View in: PubMed
    93. Buchman AS, Wang T, Yu L, Leurgans SE, Schneider JA, Bennett DA. Brain pathologies are associated with both the rate and variability of declining motor function in older adults. Acta Neuropathol. 2020 10; 140(4):587-589. PMID: 32803349.
      View in: PubMed
    94. Lamar M, Lerner AJ, James BD, Yu L, Glover CM, Wilson RS, Barnes LL. Relationship of Early-Life Residence and Educational Experience to Level and Change in Cognitive Functioning: Results of the Minority Aging Research Study. J Gerontol B Psychol Sci Soc Sci. 2020 08 13; 75(7):e81-e92. PMID: 30882155.
      View in: PubMed
    95. Nag S, Barnes LL, Yu L, Wilson RS, Bennett DA, Schneider JA. Limbic-predominant age-related TDP-43 encephalopathy in Black and White decedents. Neurology. 2020 10 13; 95(15):e2056-e2064. PMID: 32759188.
      View in: PubMed
    96. Kapasi A, Yu L, Boyle PA, Barnes LL, Bennett DA, Schneider JA. Limbic-predominant age-related TDP-43 encephalopathy, ADNC pathology, and cognitive decline in aging. Neurology. 2020 10 06; 95(14):e1951-e1962. PMID: 32753441.
      View in: PubMed
    97. Chen LY, Kang LQ, Zhou HX, Gao HQ, Zhu XF, Xu N, Yu L, Wu DP, Xue SL, Sun AN. Successful application of anti-CD19 CAR-T therapy with IL-6 knocking down to patients with central nervous system B-cell acute lymphocytic leukemia. Transl Oncol. 2020 Nov; 13(11):100838. PMID: 32745961.
      View in: PubMed
    98. Yu L, Shang D, Lang L, Liu Y, Yu M, Song D, Jia S, Han S, Li C, Liu J, Xu Y, Zhang X. TMF, a natural dihydroflavonoid isolated from Scutellaria javanica Jungh, stimulates anticancer activity of s180 cancer-bearing mice, induces apoptosis, inhibits invasion and migration on HepG-2 cells. J Ethnopharmacol. 2020 Dec 05; 263:113072. PMID: 32738393.
      View in: PubMed
    99. Shen W, Yu L, Cong A, Yang S, Wang P, Han G, Gu B, Zhang W. Silencing lncRNA AFAP1-AS1 Inhibits the Progression of Esophageal Squamous Cell Carcinoma Cells via Regulating the miR-498/VEGFA Axis. Cancer Manag Res. 2020; 12:6397-6409. PMID: 32801880.
      View in: PubMed
    100. Li Z, Qian Y, Li W, Liu L, Yu L, Liu X, Wu G, Wang Y, Luo W, Fang F, Liu Y, Song F, Cai Z, Chen W, Huang W. Human Lung Adenocarcinoma-Derived Organoid Models for Drug Screening. iScience. 2020 Aug 21; 23(8):101411. PMID: 32771979.
      View in: PubMed
    101. Li X, Shi X, Qin X, Yu L, Zhou Y, Rao C. Interlaboratory method validation of imaged capillary isoelectric focusing methodology for analysis of recombinant human erythropoietin. Anal Methods. 2020 08 14; 12(30):3836-3843. PMID: 32678383.
      View in: PubMed
    102. Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, Martini-Stoica H, Zheng H, Mei H, Zhong X, Kim JW, Dawson VL, Dawson TM, Pao PC, Tsai LH, Haure-Mirande JV, Ehrlich ME, Chakrabarty P, Levites Y, Wang X, Dammer EB, Srivastava G, Mukherjee S, Sieberts SK, Omberg L, Dang KD, Eddy JA, Snyder P, Chae Y, Amberkar S, Wei W, Hide W, Preuss C, Ergun A, Ebert PJ, Airey DC, Mostafavi S, Yu L, Klein HU. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Rep. 2020 07 14; 32(2):107908. PMID: 32668255.
      View in: PubMed
    103. Sun Y, Guo J, Yu L, Guo T, Wang J, Wang X, Chen Y. PD-L1+ exosomes from bone marrow-derived cells of tumor-bearing mice inhibit antitumor immunity. Cell Mol Immunol. 2021 10; 18(10):2402-2409. PMID: 32606317.
      View in: PubMed
    104. Glover CM, Yu L, Stewart CC, Wilson RS, Bennett DA, Boyle PA. The Association of Late Life Cognitive Activity with Healthcare and Financial Decision-Making in Community-Dwelling, Nondemented Older Adults. Am J Geriatr Psychiatry. 2021 02; 29(2):117-125. PMID: 32646635.
      View in: PubMed
    105. Yang HS, White CC, Klein HU, Yu L, Gaiteri C, Ma Y, Felsky D, Mostafavi S, Petyuk VA, Sperling RA, Ertekin-Taner N, Schneider JA, Bennett DA, De Jager PL. Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology. Neuron. 2020 08 05; 107(3):496-508.e6. PMID: 32526197.
      View in: PubMed
    106. Gao L, Lim ASP, Wong PM, Gaba A, Cui L, Yu L, Buchman AS, Bennett DA, Hu K, Li P. Fragmentation of Rest/Activity Patterns in Community-Based Elderly Individuals Predicts Incident Heart Failure. Nat Sci Sleep. 2020; 12:299-307. PMID: 32581616.
      View in: PubMed
    107. Buchman AS, Dawe RJ, Leurgans SE, Curran TA, Truty T, Yu L, Barnes LL, Hausdorff JM, Bennett DA. Different Combinations of Mobility Metrics Derived From a Wearable Sensor Are Associated With Distinct Health Outcomes in Older Adults. J Gerontol A Biol Sci Med Sci. 2020 05 22; 75(6):1176-1183. PMID: 31246244.
      View in: PubMed
    108. Liu T, Mi L, Xiong J, Orchard P, Yu Q, Yu L, Zhao XY, Meng ZX, Parker SCJ, Lin JD, Li S. BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning. Nat Commun. 2020 05 13; 11(1):2379. PMID: 32404872.
      View in: PubMed
    109. Yu L, Myers G, Engel JD. Small molecule therapeutics to treat the ß-globinopathies. Curr Opin Hematol. 2020 05; 27(3):129-140. PMID: 32167945.
      View in: PubMed
    110. Oveisgharan S, Dawe RJ, Leurgans SE, Yu L, Schneider JA, Bennett DA, Buchman AS. Total daily physical activity, brain pathologies, and parkinsonism in older adults. PLoS One. 2020; 15(4):e0232404. PMID: 32348372.
      View in: PubMed
    111. Huo Z, Yu L, Yang J, Zhu Y, Bennett DA, Zhao J. Corrigendum to brain and blood metabolome for Alzheimer's dementia: findings from a targeted metabolomics analysis [Neurobiology of Aging Volume 86, February 2020, Pages 123-133]. Neurobiol Aging. 2020 07; 91:169. PMID: 32312579.
      View in: PubMed
    112. Wilson RS, Wang T, Yu L, Bennett DA, Boyle PA. Normative Cognitive Decline in Old Age. Ann Neurol. 2020 06; 87(6):816-829. PMID: 32144793.
      View in: PubMed
    113. Oveisgharan S, Yu L, Dawe RJ, Bennett DA, Buchman AS. Total Daily Physical Activity and the Risk of Parkinsonism in Community-Dwelling Older Adults. J Gerontol A Biol Sci Med Sci. 2020 03 09; 75(4):702-711. PMID: 31046115.
      View in: PubMed
    114. Han SD, Barnes LL, Leurgans S, Yu L, Bennett DA, Boyle PA. Literacy Mediates Racial Differences in Financial and Healthcare Decision Making in Older Adults. J Am Geriatr Soc. 2020 06; 68(6):1279-1285. PMID: 32092157.
      View in: PubMed
    115. Cai Z, Zhang W, Li M, Yue Y, Yang F, Yu L, Cao X, Wang J. Correction to: TGF-beta1 gene-modified, immature dendritic cells delay the development of inflammatory bowel disease by inducing CD4(+)Foxp3(+) regulatory T cells. Cell Mol Immunol. 2020 Feb; 17(2):190-191. PMID: 31784682.
      View in: PubMed
    116. Liu YM, Cong S, Cheng Z, Hu YX, Lei Y, Zhu LL, Zhao XK, Mu M, Zhang BF, Fan LD, Yu L, Cheng ML. Platycodin D alleviates liver fibrosis and activation of hepatic stellate cells by regulating JNK/c-JUN signal pathway. Eur J Pharmacol. 2020 Jun 05; 876:172946. PMID: 31996320.
      View in: PubMed
    117. Dawe RJ, Yu L, Arfanakis K, Schneider JA, Bennett DA, Boyle PA. Late-life cognitive decline is associated with hippocampal volume, above and beyond its associations with traditional neuropathologic indices. Alzheimers Dement. 2020 01; 16(1):209-218. PMID: 31914231.
      View in: PubMed
    118. Yu L, Mottola G, Bennett DA, Boyle PA. Confidence in Financial and Health Literacy and Cognitive Health in Older Persons J Alzheimers Dis. 2020; 75(4):1229-1240. PMID: 32176649.
      View in: PubMed
    119. Lamar M, Wilson RS, Yu L, Stewart CC, Bennett DA, Boyle PA. Associations of decision making abilities with blood pressure values in older adults. J Hypertens. 2020 01; 38(1):59-64. PMID: 31503136.
      View in: PubMed
    120. Hu Y, Tan A, Yu L, Hou C, Kuang H, Wu Q, Su J, Zhou Q, Zhu Y, Zhang C, Wei W, Li L, Li W, Huang Y, Huang H, Xie X, Lu T, Zhang H, Yang X, Gao Y, Li T, Jiang Y, Mo Z. A phenomics-based approach for the detection and interpretation of shared genetic influences on 29 biochemical indices in southern Chinese men. BMC Genomics. 2019 Dec 16; 20(1):983. PMID: 31842750.
      View in: PubMed
    121. Cai G, Li L, Chen Y, Huang H, Yu L, Xu L. Complement C3 gene polymorphisms are associated with lipid levels, but not the risk of coronary artery disease: a case-control study. Lipids Health Dis. 2019 Dec 11; 18(1):217. PMID: 31829184.
      View in: PubMed
    122. Kaneshwaran K, Olah M, Tasaki S, Yu L, Bradshaw EM, Schneider JA, Buchman AS, Bennett DA, De Jager PL, Lim ASP. Sleep fragmentation, microglial aging, and cognitive impairment in adults with and without Alzheimer's dementia. Sci Adv. 2019 12; 5(12):eaax7331. PMID: 31844665.
      View in: PubMed
    123. Wilson RS, Yu L, Leurgans SE, Bennett DA, Boyle PA. Proportion of cognitive loss attributable to terminal decline. Neurology. 2020 01 07; 94(1):e42-e50. PMID: 31792096.
      View in: PubMed
    124. Yu L, Boyle PA, Dawe RJ, Bennett DA, Arfanakis K, Schneider JA. Contribution of TDP and hippocampal sclerosis to hippocampal volume loss in older-old persons. Neurology. 2020 01 14; 94(2):e142-e152. PMID: 31757868.
      View in: PubMed
    125. Yan L, Shang J, Shi X, Kang H, Liu W, Xu N, Liu Y, Chen G, Kang L, Gong F, Tang F, Yu L, Wu D, Fu C. Successful treatment of marrow failure after CARTs for myeloma by the infusion of cryopreserved stem cells. Am J Hematol. 2020 01; 95(1):E20-E23. PMID: 31637745.
      View in: PubMed
    126. Huo Z, Yu L, Yang J, Zhu Y, Bennett DA, Zhao J. Brain and blood metabolome for Alzheimer's dementia: findings from a targeted metabolomics analysis. Neurobiol Aging. 2020 02; 86:123-133. PMID: 31785839.
      View in: PubMed
    127. Li P, Lim ASP, Gao L, Hu C, Yu L, Bennett DA, Buchman AS, Hu K. More random motor activity fluctuations predict incident frailty, disability, and mortality. Sci Transl Med. 2019 10 30; 11(516). PMID: 31666398.
      View in: PubMed
    128. Kapasi A, Yu L, Stewart CC, Schneider JA, Bennett DA, Boyle PA. Association of TDP-43 Pathology With Domain-specific Literacy in Older Persons. Alzheimer Dis Assoc Disord. 2019 Oct-Dec; 33(4):315-320. PMID: 31305319.
      View in: PubMed
    129. Yu L, Wang T, Wilson RS, Leurgans S, Schneider JA, Bennett DA, Boyle PA. Common age-related neuropathologies and yearly variability in cognition. Ann Clin Transl Neurol. 2019 11; 6(11):2140-2149. PMID: 31568713.
      View in: PubMed
    130. Nag S, Yu L, VanderHorst VG, Schneider JA, Bennett DA, Buchman AS, Wilson RS. Neocortical Lewy bodies are associated with impaired odor identification in community-dwelling elders without clinical PD. J Neurol. 2019 Dec; 266(12):3108-3118. PMID: 31535271.
      View in: PubMed
    131. Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing. Nat Genet. 2019 Sep; 51(9):1423-1424. PMID: 31417202.
      View in: PubMed
    132. Li P, Yu L, Yang J, Lo MT, Hu C, Buchman AS, Bennett DA, Hu K. Interaction between the progression of Alzheimer's disease and fractal degradation. Neurobiol Aging. 2019 11; 83:21-30. PMID: 31585364.
      View in: PubMed
    133. Apodaca MC, Wright AE, Riggins AM, Harris WP, Yeung RS, Yu L, Morishima C. Characterization of a whole blood assay for quantifying myeloid-derived suppressor cells. J Immunother Cancer. 2019 08 28; 7(1):230. PMID: 31462270.
      View in: PubMed
    134. Ojelade SA, Lee TV, Giagtzoglou N, Yu L, Ugur B, Li Y, Duraine L, Zuo Z, Petyuk V, De Jager PL, Bennett DA, Arenkiel BR, Bellen HJ, Shulman JM. cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis. Cell Rep. 2019 08 13; 28(7):1799-1813.e5. PMID: 31412248.
      View in: PubMed
    135. Buchman AS, Yu L, Petyuk VA, Gaiteri C, Tasaki S, Blizinsky KD, Schneider JA, De Jager PL, Bennett DA. Cognition may link cortical IGFBP5 levels with motor function in older adults. PLoS One. 2019; 14(8):e0220968. PMID: 31404102.
      View in: PubMed
    136. van der Lee SJ, Knol MJ, Chauhan G, Satizabal CL, Smith AV, Hofer E, Bis JC, Hibar DP, Hilal S, van den Akker EB, Arfanakis K, Bernard M, Yanek LR, Amin N, Crivello F, Cheung JW, Harris TB, Saba Y, Lopez OL, Li S, van der Grond J, Yu L, Paus T, Roshchupkin GV, Amouyel P, Jahanshad N, Taylor KD, Yang Q, Mathias RA, Boehringer S, Mazoyer B, Rice K, Cheng CY, Maillard P, van Heemst D, Wong TY, Niessen WJ, Beiser AS, Beekman M, Zhao W, Nyquist PA, Chen C, Launer LJ, Psaty BM, Ikram MK, Vernooij MW, Schmidt H, Pausova Z, Becker DM, De Jager PL, Thompson PM, van Duijn CM, Bennett DA, Slagboom PE, Schmidt R, Longstreth WT, Ikram MA, Seshadri S, Debette S, Gudnason V, Adams HHH, DeCarli C. A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. Commun Biol. 2019; 2:285. PMID: 31396565.
      View in: PubMed
    137. Chen YS, Xiao HM, Wang TQ, Yu L, Feng YQ. A boronic acid modified binary matrix consisting of boron nitride and a-cyano-4-hydroxycinnamic acid for determination of cis-diols by MALDI-TOF MS. Mikrochim Acta. 2019 08 01; 186(8):591. PMID: 31372763.
      View in: PubMed
    138. Gaiteri C, Dawe R, Mostafavi S, Blizinsky KD, Tasaki S, Komashko V, Yu L, Wang Y, Schneider JA, Arfanakis K, De Jager PL, Bennett DA. Gene expression and DNA methylation are extensively coordinated with MRI-based brain microstructural characteristics. Brain Imaging Behav. 2019 Aug; 13(4):963-972. PMID: 29934819.
      View in: PubMed
    139. Kim N, Yu L, Dawe R, Petyuk VA, Gaiteri C, De Jager PL, Schneider JA, Arfanakis K, Bennett DA. Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline. Neurobiol Aging. 2019 12; 84:17-25. PMID: 31479860.
      View in: PubMed
    140. Li N, Liu Y, Duan J, Yang B, Bai H, Sun R, Yu L, Wang J. Prognostic significance of molecular characteristics of cerebrospinal fluid for non-small cell lung cancer patients with leptomeningeal metastasis. Thorac Cancer. 2019 08; 10(8):1673-1682. PMID: 31368671.
      View in: PubMed
    141. Yang JM, Zhang WH, Yang DD, Jiang H, Yu L, Gao F. Giant low-grade appendiceal mucinous neoplasm: A case report. World J Clin Cases. 2019 Jul 06; 7(13):1726-1731. PMID: 31367633.
      View in: PubMed
    142. Sun X, Sun J, Zhao D, Song Y, Yu L. Phosphatase and actin regulator 1 rs9349379 polymorphism is associated with an elevated susceptibility to coronary artery disease: a meta-analysis. J Gene Med. 2019 Jul 06; e3110. PMID: 31278837.
      View in: PubMed
    143. Stewart CC, Yu L, Lamar M, Wilson RS, Bennett DA, Boyle PA. Associations of health and financial literacy with mortality in advanced age. Aging Clin Exp Res. 2020 May; 32(5):951-957. PMID: 31273677.
      View in: PubMed
    144. Farfel JM, Yu L, Boyle PA, Leurgans S, Shah RC, Schneider JA, Bennett DA. Alzheimer's disease frequency peaks in the tenth decade and is lower afterwards. Acta Neuropathol Commun. 2019 07 03; 7(1):104. PMID: 31269985.
      View in: PubMed
    145. Yu L, Petyuk VA, Tasaki S, Boyle PA, Gaiteri C, Schneider JA, De Jager PL, Bennett DA. Association of Cortical ß-Amyloid Protein in the Absence of Insoluble Deposits With Alzheimer Disease. JAMA Neurol. 2019 07 01; 76(7):818-826. PMID: 31009033.
      View in: PubMed
    146. von Coelln R, Dawe RJ, Leurgans SE, Curran TA, Truty T, Yu L, Barnes LL, Shulman JM, Shulman LM, Bennett DA, Hausdorff JM, Buchman AS. Quantitative mobility metrics from a wearable sensor predict incident parkinsonism in older adults. Parkinsonism Relat Disord. 2019 08; 65:190-196. PMID: 31272924.
      View in: PubMed
    147. Weissberger GH, Han SD, Yu L, Barnes LL, Bennett DA, Boyle PA. Financial and health literacy discrepancies with cognition in older adults. Neuropsychology. 2019 Oct; 33(7):975-985. PMID: 31204814.
      View in: PubMed
    148. Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Chui HC, Fardo DW, Flanagan ME, Halliday G, Hokkanen SRK, Hunter S, Jicha GA, Katsumata Y, Kawas CH, Keene CD, Kovacs GG, Kukull WA, Levey AI, Makkinejad N, Montine TJ, Murayama S, Murray ME, Nag S, Rissman RA, Seeley WW, Sperling RA, White CL, Yu L, Schneider JA. Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report. Brain. 2019 06 01; 142(6):1503-1527. PMID: 31039256.
      View in: PubMed
    149. Dawe RJ, Yu L, Leurgans SE, Truty T, Curran T, Hausdorff JM, Wimmer MA, Block JA, Bennett DA, Buchman AS. Expanding instrumented gait testing in the community setting: A portable, depth-sensing camera captures joint motion in older adults. PLoS One. 2019; 14(5):e0215995. PMID: 31091267.
      View in: PubMed
    150. Boyle PA, Yu L, Schneider JA, Wilson RS, Bennett DA. Scam Awareness Related to Incident Alzheimer Dementia and Mild Cognitive Impairment: A Prospective Cohort Study. Ann Intern Med. 2019 05 21; 170(10):702-709. PMID: 30986826.
      View in: PubMed
    151. Yu L, Boyle PA, Leurgans SE, Wilson RS, Bennett DA, Buchman AS. Incident Mobility Disability, Mild Cognitive Impairment, and Mortality in Community-Dwelling Older Adults. Neuroepidemiology. 2019; 53(1-2):55-62. PMID: 30986783.
      View in: PubMed
    152. Buchman AS, Yu L, Wilson RS, Leurgans SE, Nag S, Shulman JM, Barnes LL, Schneider JA, Bennett DA. Progressive parkinsonism in older adults is related to the burden of mixed brain pathologies. Neurology. 2019 04 16; 92(16):e1821-e1830. PMID: 30894446.
      View in: PubMed
    153. Stewart CC, Yu L, Wilson RS, Bennett DA, Boyle PA. Healthcare and Financial Decision Making and Incident Adverse Cognitive Outcomes among Older Adults. J Am Geriatr Soc. 2019 08; 67(8):1590-1595. PMID: 30882910.
      View in: PubMed
    154. Capuano AW, Wilson RS, Honer WG, Petyuk VA, Leurgans SE, Yu L, Gatchel JR, Arnold S, Bennett DA, Arvanitakis Z. Brain IGFBP-5 modifies the relation of depressive symptoms to decline in cognition in older persons. J Affect Disord. 2019 05 01; 250:313-318. PMID: 30875674.
      View in: PubMed
    155. Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing. Nat Genet. 2019 03; 51(3):414-430. PMID: 30820047.
      View in: PubMed
    156. Wilson RS, Yu L, Schneider JA, Bennett DA, Boyle PA. Risk Aversion and Alzheimer Disease in Old Age. Am J Geriatr Psychiatry. 2019 08; 27(8):851-861. PMID: 30982702.
      View in: PubMed
    157. Wilson RS, Yu L, Lamar M, Schneider JA, Boyle PA, Bennett DA. Education and cognitive reserve in old age. Neurology. 2019 03 05; 92(10):e1041-e1050. PMID: 30728309.
      View in: PubMed
    158. Karasik D, Zillikens MC, Hsu YH, Aghdassi A, Akesson K, Amin N, Barroso I, Bennett DA, Bertram L, Bochud M, Borecki IB, Broer L, Buchman AS, Byberg L, Campbell H, Campos-Obando N, Cauley JA, Cawthon PM, Chambers JC, Chen Z, Cho NH, Choi HJ, Chou WC, Cummings SR, de Groot LCPGM, De Jager PL, Demuth I, Diatchenko L, Econs MJ, Eiriksdottir G, Enneman AW, Eriksson J, Eriksson JG, Estrada K, Evans DS, Feitosa MF, Fu M, Gieger C, Grallert H, Gudnason V, Lenore LJ, Hayward C, Hofman A, Homuth G, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Johnson T, Biffar R, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koller DL, Kooner JS, Kraus WE, Kritchevsky S, Kutalik Z, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Lerch MM, Lewis JR, Lill C, Lind L, Lindgren C, Liu Y, Livshits G, Ljunggren Ö, Loos RJF, Lorentzon M, Luan J, Luben RN, Malkin I, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Nethander M, Newman AB, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Peacock M, Perola M, Peters A, Prince RL, Psaty BM, Räikkönen K, Ralston SH, Ripatti S, Rivadeneira F, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schipf S, Shin CS, Smith AV, Smith SB, Soranzo N, Spector TD, Stancáková A, Stefansson K, Steinhagen-Thiessen E, Stolk L, Streeten EA, Styrkarsdottir U, Swart KMA, Thompson P, Thomson CA, Thorleifsson G, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Uitterlinden AG, van Duijn CM, van Schoor NM, Vandenput L, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, J Wareham N, Waterworth D, Weedon MN, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Yerges-Armstrong LM, Yu L, Zhang W, Zhao JH, Zhou Y, Nielson CM, Harris TB, Demissie S, Kiel DP, Ohlsson C. Disentangling the genetics of lean mass. Am J Clin Nutr. 2019 02 01; 109(2):276-287. PMID: 30721968.
      View in: PubMed
    159. Wilson RS, Yang J, Yu L, Leurgans SE, Capuano AW, Schneider JA, Bennett DA, Boyle PA. Postmortem neurodegenerative markers and trajectories of decline in cognitive systems. Neurology. 2019 02 19; 92(8):e831-e840. PMID: 30674595.
      View in: PubMed
    160. Buchman AS, Yu L, Wilson RS, Lim A, Dawe RJ, Gaiteri C, Leurgans SE, Schneider JA, Bennett DA. Physical activity, common brain pathologies, and cognition in community-dwelling older adults. Neurology. 2019 02 19; 92(8):e811-e822. PMID: 30651386.
      View in: PubMed
    161. Yang M, Li J, Sun R, Wang Y, Xu H, Yang B, Wu X, Yu L. Comparison between direct factor Xa inhibitors and low-molecular-weight heparin for efficacy and safety in the treatment of cancer-associated venous thromboembolism: A meta-analysis. J Cancer Res Ther. 2019; 15(7):1541-1546. PMID: 31939435.
      View in: PubMed
    162. Huo Z, Zhu Y, Yu L, Yang J, De Jager P, Bennett DA, Zhao J. DNA methylation variability in Alzheimer's disease. Neurobiol Aging. 2019 04; 76:35-44. PMID: 30660039.
      View in: PubMed
    163. Boyle PA, Yu L, Leurgans SE, Wilson RS, Brookmeyer R, Schneider JA, Bennett DA. Attributable risk of Alzheimer's dementia attributed to age-related neuropathologies. Ann Neurol. 2019 01; 85(1):114-124. PMID: 30421454.
      View in: PubMed
    164. Lamar M, Wilson RS, Yu L, James BD, Stewart CC, Bennett DA, Boyle PA. Associations of literacy with diabetes indicators in older adults. J Epidemiol Community Health. 2019 03; 73(3):250-255. PMID: 30530520.
      View in: PubMed
    165. Oveisgharan S, Arvanitakis Z, Yu L, Farfel J, Schneider JA, Bennett DA. Sex differences in Alzheimer's disease and common neuropathologies of aging. Acta Neuropathol. 2018 12; 136(6):887-900. PMID: 30334074.
      View in: PubMed
    166. Xu N, Fang W, Mu L, Tang Y, Gao L, Ren S, Cao D, Zhou L, Zhang A, Liu D, Zhou C, Wong KK, Yu L, Zhang L, Chen L. Correction: Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer. Oncotarget. 2018 10 16; 9(81):35284. PMID: 30443296.
      View in: PubMed
    167. Gao L, Jiang Y, Mu L, Liu Y, Wang F, Wang P, Zhang A, Tang N, Chen T, Luo M, Yu L, Gao S, Chen L. Author Correction: Efficient Generation of Mice with Consistent Transgene Expression by FEEST. Sci Rep. 2018 Oct 16; 8(1):15259. PMID: 30327478.
      View in: PubMed
    168. Lamar M, Yu L, Rubin LH, James BD, Barnes LL, Farfel JM, Gaiteri C, Buchman AS, Bennett DA, Schneider JA. APOE genotypes as a risk factor for age-dependent accumulation of cerebrovascular disease in older adults. Alzheimers Dement. 2019 02; 15(2):258-266. PMID: 30321502.
      View in: PubMed
    169. Lim ASP, Gaiteri C, Yu L, Sohail S, Swardfager W, Tasaki S, Schneider JA, Paquet C, Stuss DT, Masellis M, Black SE, Hugon J, Buchman AS, Barnes LL, Bennett DA, De Jager PL. Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts. PLoS Med. 2018 09; 15(9):e1002647. PMID: 30180184.
      View in: PubMed
    170. Gao M, Yang X, Liu L, Fei N, Xi Y, Guo F, Yan F, Meng P, Yu L, Liu P, Qin W, Yin H, Yuan J. Abnormal White Matter Microstructure in Lifelong Premature Ejaculation Patients Identified by Tract-Based Spatial Statistical Analysis. J Sex Med. 2018 09; 15(9):1272-1279. PMID: 30224018.
      View in: PubMed
    171. Tasaki S, Gaiteri C, Mostafavi S, Yu L, Wang Y, De Jager PL, Bennett DA. Multi-omic Directed Networks Describe Features of Gene Regulation in Aged Brains and Expand the Set of Genes Driving Cognitive Decline. Front Genet. 2018; 9:294. PMID: 30140277.
      View in: PubMed
    172. De Jager PL, Ma Y, McCabe C, Xu J, Vardarajan BN, Felsky D, Klein HU, White CC, Peters MA, Lodgson B, Nejad P, Tang A, Mangravite LM, Yu L, Gaiteri C, Mostafavi S, Schneider JA, Bennett DA. A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research. Sci Data. 2018 08 07; 5:180142. PMID: 30084846.
      View in: PubMed
    173. Yang HS, Yu L, White CC, Chibnik LB, Chhatwal JP, Sperling RA, Bennett DA, Schneider JA, De Jager PL. Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE e4 haplotype status: a community-based cohort study. Lancet Neurol. 2018 09; 17(9):773-781. PMID: 30093249.
      View in: PubMed
    174. Han SD, Arfanakis K, Fleischman DA, Yu L, Bennett DA, Boyle PA. White matter correlates of temporal discounting in older adults. Brain Struct Funct. 2018 Nov; 223(8):3653-3663. PMID: 29992469.
      View in: PubMed
    175. Yu L, Petyuk VA, Gaiteri C, Mostafavi S, Young-Pearse T, Shah RC, Buchman AS, Schneider JA, Piehowski PD, Sontag RL, Fillmore TL, Shi T, Smith RD, De Jager PL, Bennett DA. Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia. Ann Neurol. 2018 07; 84(1):78-88. PMID: 29908079.
      View in: PubMed
    176. James BD, Wilson RS, Shah RC, Yu L, Arvanitakis Z, Bennett DA, Boyle PA. Association of Financial Literacy With Hospitalization in Community-dwelling Older Adults. Med Care. 2018 07; 56(7):596-602. PMID: 29901572.
      View in: PubMed
    177. Power MC, Mormino E, Soldan A, James BD, Yu L, Armstrong NM, Bangen KJ, Delano-Wood L, Lamar M, Lim YY, Nudelman K, Zahodne L, Gross AL, Mungas D, Widaman KF, Schneider J. Combined neuropathological pathways account for age-related risk of dementia. Ann Neurol. 2018 07; 84(1):10-22. PMID: 29944741.
      View in: PubMed
    178. Stewart CC, Boyle PA, James BD, Yu L, Han SD, Bennett DA. Associations of APOE e4 With Health and Financial Literacy Among Community-Based Older Adults Without Dementia. J Gerontol B Psychol Sci Soc Sci. 2018 06 14; 73(5):778-786. PMID: 27174891.
      View in: PubMed
    179. Mostafavi S, Gaiteri C, Sullivan SE, White CC, Tasaki S, Xu J, Taga M, Klein HU, Patrick E, Komashko V, McCabe C, Smith R, Bradshaw EM, Root DE, Regev A, Yu L, Chibnik LB, Schneider JA, Young-Pearse TL, Bennett DA, De Jager PL. A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease. Nat Neurosci. 2018 06; 21(6):811-819. PMID: 29802388.
      View in: PubMed
    180. Dawe RJ, Yu L, Schneider JA, Arfanakis K, Bennett DA, Boyle PA. Postmortem brain MRI is related to cognitive decline, independent of cerebral vessel disease in older adults. Neurobiol Aging. 2018 09; 69:177-184. PMID: 29908416.
      View in: PubMed
    181. Oveisgharan S, Buchman AS, Yu L, Farfel J, Hachinski V, Gaiteri C, De Jager PL, Schneider JA, Bennett DA. APOE e2e4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults. Neurology. 2018 06 12; 90(24):e2127-e2134. PMID: 29752306.
      View in: PubMed
    182. Li P, Yu L, Lim ASP, Buchman AS, Scheer FAJL, Shea SA, Schneider JA, Bennett DA, Hu K. Fractal regulation and incident Alzheimer's disease in elderly individuals. Alzheimers Dement. 2018 09; 14(9):1114-1125. PMID: 29733807.
      View in: PubMed
    183. Nag S, Yu L, Boyle PA, Leurgans SE, Bennett DA, Schneider JA. TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer's disease. Acta Neuropathol Commun. 2018 05 01; 6(1):33. PMID: 29716643.
      View in: PubMed
    184. Buchman AS, Dawe RJ, Yu L, Lim A, Wilson RS, Schneider JA, Bennett DA. Brain pathology is related to total daily physical activity in older adults. Neurology. 2018 05 22; 90(21):e1911-e1919. PMID: 29695600.
      View in: PubMed
    185. Wilson RS, Capuano AW, Yu L, Yang J, Kim N, Leurgans SE, Lamar M, Schneider JA, Bennett DA, Boyle PA. Neurodegenerative disease and cognitive retest learning. Neurobiol Aging. 2018 06; 66:122-130. PMID: 29558667.
      View in: PubMed
    186. Stewart CC, Yu L, Wilson RS, Bennett DA, Boyle PA. Correlates of healthcare and financial decision making among older adults without dementia. Health Psychol. 2018 07; 37(7):618-626. PMID: 29565601.
      View in: PubMed
    187. Cowper B, Li X, Yu L, Zhou Y, Fan WH, Rao CM. Comprehensive glycan analysis of twelve recombinant human erythropoietin preparations from manufacturers in China and Japan. J Pharm Biomed Anal. 2018 May 10; 153:214-220. PMID: 29502007.
      View in: PubMed
    188. Benedet AL, Yu L, Labbe A, Mathotaarachchi S, Pascoal TA, Shin M, Kang MS, Gauthier S, Rouleau GA, Poirier J, Bennett DA, Rosa-Neto P. CYP2C19 variant mitigates Alzheimer disease pathophysiology in vivo and postmortem. Neurol Genet. 2018 Feb; 4(1):e216. PMID: 29473050.
      View in: PubMed
    189. Boyle PA, Yu L, Wilson RS, Leurgans SE, Schneider JA, Bennett DA. Person-specific contribution of neuropathologies to cognitive loss in old age. Ann Neurol. 2018 01; 83(1):74-83. PMID: 29244218.
      View in: PubMed
    190. Canli T, Yu L, Yu X, Zhao H, Fleischman D, Wilson RS, De Jager PL, Bennett DA. Loneliness 5 years ante-mortem is associated with disease-related differential gene expression in postmortem dorsolateral prefrontal cortex. Transl Psychiatry. 2018 01 10; 8(1):2. PMID: 29317593.
      View in: PubMed
    191. Yu L, Dawe RJ, Boyle PA, Gaiteri C, Yang J, Buchman AS, Schneider JA, Arfanakis K, De Jager PL, Bennett DA. Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline. JAMA Neurol. 2017 12 01; 74(12):1473-1480. PMID: 29084334.
      View in: PubMed
    192. Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, Thorleifsson G, Vandenput L, Hua Zhao J, Zhang W, Aghdassi A, Åkesson K, Amin N, Baier LJ, Barroso I, Bennett DA, Bertram L, Biffar R, Bochud M, Boehnke M, Borecki IB, Buchman AS, Byberg L, Campbell H, Campos Obanda N, Cauley JA, Cawthon PM, Cederberg H, Chen Z, Cho NH, Jin Choi H, Claussnitzer M, Collins F, Cummings SR, De Jager PL, Demuth I, Dhonukshe-Rutten RAM, Diatchenko L, Eiriksdottir G, Enneman AW, Erdos M, Eriksson JG, Eriksson J, Estrada K, Evans DS, Feitosa MF, Fu M, Garcia M, Gieger C, Girke T, Glazer NL, Grallert H, Grewal J, Han BG, Hanson RL, Hayward C, Hofman A, Hoffman EP, Homuth G, Hsueh WC, Hubal MJ, Hubbard A, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koistinen HA, Kraus WE, Kritchevsky S, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Launer LJ, Lee JY, Lerch MM, Lewis JR, Lind L, Lindgren C, Liu Y, Liu T, Liu Y, Ljunggren Ö, Lorentzon M, Luben RN, Maixner W, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Melov S, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Newman A, Nielson CM, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Parker SCJ, Peacock M, Perola M, Peters A, Polasek O, Prince RL, Räikkönen K, Ralston SH, Ripatti S, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schadt EE, Schipf S, Scott L, Sehmi J, Shen J, Soo Shin C, Sigurdsson G, Smith S, Soranzo N, Stancáková A, Steinhagen-Thiessen E, Streeten EA, Styrkarsdottir U, Swart KMA, Tan ST, Tarnopolsky MA, Thompson P, Thomson CA, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Tuomilehto J, van Schoor NM, Verma A, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, Weedon MN, Welch R, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Xie W, Yu L, Zhou Y, Chambers JC, Döring A, van Duijn CM, Econs MJ, Gudnason V, Kooner JS, Psaty BM, Spector TD, Stefansson K, Rivadeneira F, Uitterlinden AG, Wareham NJ, Ossowski V, Waterworth D, Loos RJF, Karasik D, Harris TB, Ohlsson C, Kiel DP. Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nat Commun. 2017 11 07; 8(1):1414. PMID: 29116125.
      View in: PubMed
    193. Sohail S, Yu L, Schneider JA, Bennett DA, Buchman AS, Lim ASP. Sleep fragmentation and Parkinson's disease pathology in older adults without Parkinson's disease. Mov Disord. 2017 Dec; 32(12):1729-1737. PMID: 29082554.
      View in: PubMed
    194. Ng B, White CC, Klein HU, Sieberts SK, McCabe C, Patrick E, Xu J, Yu L, Gaiteri C, Bennett DA, Mostafavi S, De Jager PL. An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome. Nat Neurosci. 2017 Oct; 20(10):1418-1426. PMID: 28869584.
      View in: PubMed
    195. Vardarajan BN, Tosto G, Lefort R, Yu L, Bennett DA, De Jager PL, Barral S, Reyes-Dumeyer D, Nagy PL, Lee JH, Cheng R, Medrano M, Lantigua R, Rogaeva E, St George-Hyslop P, Mayeux R. Ultra-rare mutations in SRCAP segregate in Caribbean Hispanic families with Alzheimer disease. Neurol Genet. 2017 Oct; 3(5):e178. PMID: 28852706.
      View in: PubMed
    196. Guo F, Xi YB, Gao M, Liu L, Fei NB, Qin W, Li C, Cui LB, Yan F, Yu L, Yuan JL, Yin H. Alterations in cortical thickness in nonmedicated premature ejaculation patients: A morphometric MRI study. J Magn Reson Imaging. 2018 03; 47(3):656-662. PMID: 28736888.
      View in: PubMed
    197. Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, Thorleifsson G, Vandenput L, Hua Zhao J, Zhang W, Aghdassi A, Åkesson K, Amin N, Baier LJ, Barroso I, Bennett DA, Bertram L, Biffar R, Bochud M, Boehnke M, Borecki IB, Buchman AS, Byberg L, Campbell H, Campos Obanda N, Cauley JA, Cawthon PM, Cederberg H, Chen Z, Cho NH, Jin Choi H, Claussnitzer M, Collins F, Cummings SR, De Jager PL, Demuth I, Dhonukshe-Rutten RAM, Diatchenko L, Eiriksdottir G, Enneman AW, Erdos M, Eriksson JG, Eriksson J, Estrada K, Evans DS, Feitosa MF, Fu M, Garcia M, Gieger C, Girke T, Glazer NL, Grallert H, Grewal J, Han BG, Hanson RL, Hayward C, Hofman A, Hoffman EP, Homuth G, Hsueh WC, Hubal MJ, Hubbard A, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koistinen HA, Kraus WE, Kritchevsky S, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Launer LJ, Lee JY, Lerch MM, Lewis JR, Lind L, Lindgren C, Liu Y, Liu T, Liu Y, Ljunggren Ö, Lorentzon M, Luben RN, Maixner W, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Melov S, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Newman A, Nielson CM, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Parker SCJ, Peacock M, Perola M, Peters A, Polasek O, Prince RL, Räikkönen K, Ralston SH, Ripatti S, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schadt EE, Schipf S, Scott L, Sehmi J, Shen J, Soo Shin C, Sigurdsson G, Smith S, Soranzo N, Stancáková A, Steinhagen-Thiessen E, Streeten EA, Styrkarsdottir U, Swart KMA, Tan ST, Tarnopolsky MA, Thompson P, Thomson CA, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Tuomilehto J, van Schoor NM, Verma A, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, Weedon MN, Welch R, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Xie W, Yu L, Zhou Y, Chambers JC, Döring A, van Duijn CM, Econs MJ, Gudnason V, Kooner JS, Psaty BM, Spector TD, Stefansson K, Rivadeneira F, Uitterlinden AG, Wareham NJ, Ossowski V, Waterworth D, Loos RJF, Karasik D, Harris TB, Ohlsson C, Kiel DP. Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nat Commun. 2017 07 19; 8(1):80. PMID: 28724990.
      View in: PubMed
    198. Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Longstreth WT, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Genet. 2017 09; 49(9):1373-1384. PMID: 28714976.
      View in: PubMed
    199. Yu L, Lutz MW, Wilson RS, Burns DK, Roses AD, Saunders AM, Yang J, Gaiteri C, De Jager PL, Barnes LL, Bennett DA. APOE e4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans. PLoS One. 2017; 12(7):e0180356. PMID: 28672022.
      View in: PubMed
    200. Yu L, Wilson RS, Han SD, Leurgans S, Bennett DA, Boyle PA. Decline in Literacy and Incident AD Dementia Among Community-Dwelling Older Persons. J Aging Health. 2018 10; 30(9):1389-1405. PMID: 28645223.
      View in: PubMed
    201. Yu L, Lutz MW, Farfel JM, Wilson RS, Burns DK, Saunders AM, De Jager PL, Barnes LL, Schneider JA, Bennett DA. Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline. Alzheimers Dement. 2017 Dec; 13(12):1380-1388. PMID: 28624335.
      View in: PubMed
    202. White CC, Yang HS, Yu L, Chibnik LB, Dawe RJ, Yang J, Klein HU, Felsky D, Ramos-Miguel A, Arfanakis K, Honer WG, Sperling RA, Schneider JA, Bennett DA, De Jager PL. Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data. PLoS Med. 2017 04; 14(4):e1002287. PMID: 28441426.
      View in: PubMed
    203. Lim AS, Klein HU, Yu L, Chibnik LB, Ali S, Xu J, Bennett DA, De Jager PL. Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer's disease. Nat Commun. 2017 04 03; 8:14931. PMID: 28368004.
      View in: PubMed
    204. Abner EL, Kryscio RJ, Schmitt FA, Fardo DW, Moga DC, Ighodaro ET, Jicha GA, Yu L, Dodge HH, Xiong C, Woltjer RL, Schneider JA, Cairns NJ, Bennett DA, Nelson PT. Outcomes after diagnosis of mild cognitive impairment in a large autopsy series. Ann Neurol. 2017 Apr; 81(4):549-559. PMID: 28224671.
      View in: PubMed
    205. Boyle PA, Yang J, Yu L, Leurgans SE, Capuano AW, Schneider JA, Wilson RS, Bennett DA. Varied effects of age-related neuropathologies on the trajectory of late life cognitive decline. Brain. 2017 03 01; 140(3):804-812. PMID: 28082297.
      View in: PubMed
    206. Yu L, Lutz MW, Wilson RS, Burns DK, Roses AD, Saunders AM, Gaiteri C, De Jager PL, Barnes LL, Bennett DA. TOMM40'523 variant and cognitive decline in older persons with APOE e3/3 genotype. Neurology. 2017 Feb 14; 88(7):661-668. PMID: 28108637.
      View in: PubMed
    207. Nag S, Yu L, Wilson RS, Chen EY, Bennett DA, Schneider JA. TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD. Neurology. 2017 Feb 14; 88(7):653-660. PMID: 28087828.
      View in: PubMed
    208. Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellström D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SL, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G. The complex genetics of gait speed: genome-wide meta-analysis approach. Aging (Albany NY). 2017 01 10; 9(1):209-246. PMID: 28077804.
      View in: PubMed
    209. Yu L, Wilson RS, Schneider JA, Bennett DA, Boyle PA. Financial and Health Literacy Predict Incident Alzheimer's Disease Dementia and Pathology. J Alzheimers Dis. 2017; 56(4):1485-1493. PMID: 28157101.
      View in: PubMed
    210. Dodge HH, Zhu J, Woltjer R, Nelson PT, Bennett DA, Cairns NJ, Fardo DW, Kaye JA, Lyons DE, Mattek N, Schneider JA, Silbert LC, Xiong C, Yu L, Schmitt FA, Kryscio RJ, Abner EL. Risk of incident clinical diagnosis of Alzheimer's disease-type dementia attributable to pathology-confirmed vascular disease. Alzheimers Dement. 2017 Jun; 13(6):613-623. PMID: 28017827.
      View in: PubMed
    211. Raj T, Chibnik LB, McCabe C, Wong A, Replogle JM, Yu L, Gao S, Unverzagt FW, Stranger B, Murrell J, Barnes L, Hendrie HC, Foroud T, Krichevsky A, Bennett DA, Hall KS, Evans DA, De Jager PL. Genetic architecture of age-related cognitive decline in African Americans. Neurol Genet. 2017 Feb; 3(1):e125. PMID: 28078323.
      View in: PubMed
    212. Dong J, Wyss A, Yang J, Price TR, Nicolas A, Nalls M, Tranah G, Franceschini N, Xu Z, Schulte C, Alonso A, Cummings SR, Fornage M, Zaykin D, Li L, Huang X, Kritchevsky S, Liu Y, Gasser T, Wilson RS, De Jager PL, Singleton AB, Pinto JM, Harris T, Mosley TH, Bennett DA, London S, Yu L, Chen H. Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. Mol Neurobiol. 2017 Dec; 54(10):8021-8032. PMID: 27878761.
      View in: PubMed
    213. Do Carmo S, Hanzel CE, Jacobs ML, Machnes Z, Iulita MF, Yang J, Yu L, Ducatenzeiler A, Danik M, Breuillaud LS, Bennett DA, Szyf M, Cuello AC. Rescue of Early bace-1 and Global DNA Demethylation by S-Adenosylmethionine Reduces Amyloid Pathology and Improves Cognition in an Alzheimer's Model. Sci Rep. 2016 Sep 29; 6:34051. PMID: 27681803.
      View in: PubMed
    214. Yu L, Dawe RJ, Buchman AS, Boyle PA, Schneider JA, Arfanakis K, Bennett DA. Ex vivo MRI transverse relaxation in community based older persons with and without Alzheimer's dementia. Behav Brain Res. 2017 03 30; 322(Pt B):233-240. PMID: 27596378.
      View in: PubMed
    215. Boyle PA, Yu L, Fleischman DA, Leurgans S, Yang J, Wilson RS, Schneider JA, Arvanitakis Z, Arfanakis K, Bennett DA. White matter hyperintensities, incident mild cognitive impairment, and cognitive decline in old age. Ann Clin Transl Neurol. 2016 10; 3(10):791-800. PMID: 27752514.
      View in: PubMed
    216. Buchman AS, Leurgans SE, Yu L, Wilson RS, Lim AS, James BD, Shulman JM, Bennett DA. Incident parkinsonism in older adults without Parkinson disease. Neurology. 2016 Sep 06; 87(10):1036-44. PMID: 27488597.
      View in: PubMed
    217. Valenca GT, Srivastava GP, Oliveira-Filho J, White CC, Yu L, Schneider JA, Buchman AS, Shulman JM, Bennett DA, De Jager PL. The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults. PLoS One. 2016; 11(7):e0157452. PMID: 27458716.
      View in: PubMed
    218. Farfel JM, Yu L, Buchman AS, Schneider JA, De Jager PL, Bennett DA. Relation of genomic variants for Alzheimer disease dementia to common neuropathologies. Neurology. 2016 Aug 02; 87(5):489-96. PMID: 27371493.
      View in: PubMed
    219. Matteini AM, Tanaka T, Karasik D, Atzmon G, Chou WC, Eicher JD, Johnson AD, Arnold AM, Callisaya ML, Davies G, Evans DS, Holtfreter B, Lohman K, Lunetta KL, Mangino M, Smith AV, Smith JA, Teumer A, Yu L, Arking DE, Buchman AS, Chibinik LB, De Jager PL, Evans DA, Faul JD, Garcia ME, Gillham-Nasenya I, Gudnason V, Hofman A, Hsu YH, Ittermann T, Lahousse L, Liewald DC, Liu Y, Lopez L, Rivadeneira F, Rotter JI, Siggeirsdottir K, Starr JM, Thomson R, Tranah GJ, Uitterlinden AG, Völker U, Völzke H, Weir DR, Yaffe K, Zhao W, Zhuang WV, Zmuda JM, Bennett DA, Cummings SR, Deary IJ, Ferrucci L, Harris TB, Kardia SL, Kocher T, Kritchevsky SB, Psaty BM, Seshadri S, Spector TD, Srikanth VK, Windham BG, Zillikens MC, Newman AB, Walston JD, Kiel DP, Murabito JM. GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium. Aging Cell. 2016 10; 15(5):792-800. PMID: 27325353.
      View in: PubMed
    220. Chouraki V, Reitz C, Maury F, Bis JC, Bellenguez C, Yu L, Jakobsdottir J, Mukherjee S, Adams HH, Choi SH, Larson EB, Fitzpatrick A, Uitterlinden AG, de Jager PL, Hofman A, Gudnason V, Vardarajan B, Ibrahim-Verbaas C, van der Lee SJ, Lopez O, Dartigues JF, Berr C, Amouyel P, Bennett DA, van Duijn C, DeStefano AL, Launer LJ, Ikram MA, Crane PK, Lambert JC, Mayeux R, Seshadri S. Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease. J Alzheimers Dis. 2016 06 18; 53(3):921-32. PMID: 27340842.
      View in: PubMed
    221. Dawe RJ, Yu L, Leurgans SE, Schneider JA, Buchman AS, Arfanakis K, Bennett DA, Boyle PA. Postmortem MRI: a novel window into the neurobiology of late life cognitive decline. Neurobiol Aging. 2016 09; 45:169-177. PMID: 27459937.
      View in: PubMed
    222. Wilson RS, Yu L, James BD, Bennett DA, Boyle PA. Association of financial and health literacy with cognitive health in old age. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2017 Mar; 24(2):186-197. PMID: 27263546.
      View in: PubMed
    223. Ali YO, Allen HM, Yu L, Li-Kroeger D, Bakhshizadehmahmoudi D, Hatcher A, McCabe C, Xu J, Bjorklund N, Taglialatela G, Bennett DA, De Jager PL, Shulman JM, Bellen HJ, Lu HC. NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies. PLoS Biol. 2016 06; 14(6):e1002472. PMID: 27254664.
      View in: PubMed
    224. Duke Han S, Boyle PA, Yu L, Arfanakis K, James BD, Fleischman DA, Bennett DA. Grey matter correlates of susceptibility to scams in community-dwelling older adults. Brain Imaging Behav. 2016 06; 10(2):524-32. PMID: 26100658.
      View in: PubMed
    225. Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, Buchwald J, Cavadino A, Frazier-Wood AC, Furlotte NA, Garfield V, Geisel MH, Gonzalez JR, Haitjema S, Karlsson R, van der Laan SW, Ladwig KH, Lahti J, van der Lee SJ, Lind PA, Liu T, Matteson L, Mihailov E, Miller MB, Minica CC, Nolte IM, Mook-Kanamori D, van der Most PJ, Oldmeadow C, Qian Y, Raitakari O, Rawal R, Realo A, Rueedi R, Schmidt B, Smith AV, Stergiakouli E, Tanaka T, Taylor K, Thorleifsson G, Wedenoja J, Wellmann J, Westra HJ, Willems SM, Zhao W. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet. 2016 06; 48(6):624-33. PMID: 27089181.
      View in: PubMed
    226. Yu L, Chibnik LB, Yang J, McCabe C, Xu J, Schneider JA, De Jager PL, Bennett DA. Methylation profiles in peripheral blood CD4+ lymphocytes versus brain: The relation to Alzheimer's disease pathology. Alzheimers Dement. 2016 09; 12(9):942-951. PMID: 27016692.
      View in: PubMed
    227. Han SD, Boyle PA, Arfanakis K, Fleischman D, Yu L, James BD, Bennett DA. Financial literacy is associated with white matter integrity in old age. Neuroimage. 2016 Apr 15; 130:223-229. PMID: 26899784.
      View in: PubMed
    228. Lu Y, Day FR, Gustafsson S, Buchkovich ML, Na J, Bataille V, Cousminer DL, Dastani Z, Drong AW, Esko T, Evans DM, Falchi M, Feitosa MF, Ferreira T, Hedman ÅK, Haring R, Hysi PG, Iles MM, Justice AE, Kanoni S, Lagou V, Li R, Li X, Locke A, Lu C, Mägi R, Perry JR, Pers TH, Qi Q, Sanna M, Schmidt EM, Scott WR, Shungin D, Teumer A, Vinkhuyzen AA, Walker RW, Westra HJ, Zhang M, Zhang W, Zhao JH, Zhu Z, Afzal U, Ahluwalia TS, Bakker SJ, Bellis C, Bonnefond A, Borodulin K, Buchman AS, Cederholm T, Choh AC, Choi HJ, Curran JE, de Groot LC, De Jager PL, Dhonukshe-Rutten RA, Enneman AW, Eury E, Evans DS, Forsen T, Friedrich N, Fumeron F, Garcia ME, Gärtner S, Han BG, Havulinna AS, Hayward C, Hernandez D, Hillege H, Ittermann T, Kent JW, Kolcic I, Laatikainen T, Lahti J, Mateo Leach I, Lee CG, Lee JY, Liu T, Liu Y, Lobbens S, Loh M, Lyytikäinen LP, Medina-Gomez C, Michaëlsson K, Nalls MA, Nielson CM, Oozageer L, Pascoe L, Paternoster L, Polašek O, Ripatti S, Sarzynski MA, Shin CS, Narancic NS, Spira D, Srikanth P, Steinhagen-Thiessen E, Sung YJ, Swart KM, Taittonen L, Tanaka T, Tikkanen E, van der Velde N, van Schoor NM, Verweij N, Wright AF, Yu L, Zmuda JM, Eklund N, Forrester T, Grarup N, Jackson AU, Kristiansson K, Kuulasmaa T, Kuusisto J, Lichtner P, Luan J, Mahajan A, Männistö S, Palmer CD, Ried JS, Scott RA, Stancáková A, Wagner PJ, Demirkan A, Döring A, Gudnason V, Kiel DP, Kühnel B, Mangino M, Mcknight B, Menni C, O'Connell JR, Oostra BA, Shuldiner AR, Song K, Vandenput L, van Duijn CM, Vollenweider P, White CC, Boehnke M, Boettcher Y, Cooper RS, Forouhi NG, Gieger C, Grallert H, Hingorani A, Jørgensen T, Jousilahti P, Kivimaki M, Kumari M, Laakso M, Langenberg C, Linneberg A, Luke A, Mckenzie CA, Palotie A, Pedersen O, Peters A, Strauch K, Tayo BO, Wareham NJ, Bennett DA, Bertram L, Blangero J, Blüher M, Bouchard C, Campbell H, Cho NH, Cummings SR, Czerwinski SA, Demuth I, Eckardt R, Eriksson JG, Ferrucci L, Franco OH, Froguel P, Gansevoort RT, Hansen T, Harris TB, Hastie N, Heliövaara M, Hofman A, Jordan JM, Jula A, Kähönen M, Kajantie E, Knekt PB, Koskinen S, Kovacs P, Lehtimäki T, Lind L, Liu Y, Orwoll ES, Osmond C, Perola M, Pérusse L, Raitakari OT, Rankinen T, Rao DC, Rice TK, Rivadeneira F, Rudan I, Salomaa V, Sørensen TI, Stumvoll M, Tönjes A, Towne B, Tranah GJ, Tremblay A, Uitterlinden AG, van der Harst P, Vartiainen E, Viikari JS, Vitart V, Vohl MC, Völzke H, Walker M, Wallaschofski H, Wild S, Wilson JF, Yengo L, Bishop DT, Borecki IB, Chambers JC, Cupples LA, Dehghan A, Deloukas P, Fatemifar G, Fox C, Furey TS, Franke L, Han J, Hunter DJ, Karjalainen J, Karpe F, Kaplan RC, Kooner JS, McCarthy MI, Murabito JM, Morris AP, Bishop JA, North KE, Ohlsson C, Ong KK, Prokopenko I, Richards JB, Schadt EE, Spector TD, Widén E, Willer CJ, Yang J, Ingelsson E, Mohlke KL, Hirschhorn JN, Pospisilik JA, Zillikens MC, Lindgren C, Kilpeläinen TO, Loos RJ. New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nat Commun. 2016 Feb 01; 7:10495. PMID: 26833246.
      View in: PubMed
    229. Buchman AS, Yu L, Boyle PA, Schneider JA, De Jager PL, Bennett DA. Higher brain BDNF gene expression is associated with slower cognitive decline in older adults. Neurology. 2016 Feb 23; 86(8):735-41. PMID: 26819457.
      View in: PubMed
    230. Xu N, Fang W, Mu L, Tang Y, Gao L, Ren S, Cao D, Zhou L, Zhang A, Liu D, Zhou C, Wong KK, Yu L, Zhang L, Chen L. Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer. Oncotarget. 2016 Jan 26; 7(4):3884-96. PMID: 26646697.
      View in: PubMed
    231. Abner EL, Nelson PT, Kryscio RJ, Schmitt FA, Fardo DW, Woltjer RL, Cairns NJ, Yu L, Dodge HH, Xiong C, Masaki K, Tyas SL, Bennett DA, Schneider JA, Arvanitakis Z. Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology. Alzheimers Dement. 2016 08; 12(8):882-9. PMID: 26812281.
      View in: PubMed
    232. Lim AS, Yu L, Schneider JA, Bennett DA, Buchman AS. Sleep Fragmentation, Cerebral Arteriolosclerosis, and Brain Infarct Pathology in Community-Dwelling Older People. Stroke. 2016 Feb; 47(2):516-8. PMID: 26768207.
      View in: PubMed
    233. Han SD, Boyle PA, James BD, Yu L, Bennett DA. Mild Cognitive Impairment and Susceptibility to Scams in Old Age. J Alzheimers Dis. 2016; 49(3):845-51. PMID: 26519434.
      View in: PubMed
    234. Lim AS, Fleischman DA, Dawe RJ, Yu L, Arfanakis K, Buchman AS, Bennett DA. Regional Neocortical Gray Matter Structure and Sleep Fragmentation in Older Adults. Sleep. 2016 Jan 01; 39(1):227-35. PMID: 26350471.
      View in: PubMed
    235. Gao L, Jiang Y, Mu L, Liu Y, Wang F, Wang P, Zhang A, Tang N, Chen T, Luo M, Yu L, Gao S, Chen L. Efficient Generation of Mice with Consistent Transgene Expression by FEEST. Sci Rep. 2015 Nov 17; 5:16284. PMID: 26573149.
      View in: PubMed
    236. Boyle PA, Yu L, Nag S, Leurgans S, Wilson RS, Bennett DA, Schneider JA. Cerebral amyloid angiopathy and cognitive outcomes in community-based older persons. Neurology. 2015 Dec 01; 85(22):1930-6. PMID: 26537052.
      View in: PubMed
    237. Buchman AS, Wilson RS, Yu L, Boyle PA, Bennett DA, Barnes LL. Motor Function Is Associated With Incident Disability in Older African Americans. J Gerontol A Biol Sci Med Sci. 2016 May; 71(5):696-702. PMID: 26525087.
      View in: PubMed
    238. Dong J, Yang J, Tranah G, Franceschini N, Parimi N, Alkorta-Aranburu G, Xu Z, Alonso A, Cummings SR, Fornage M, Huang X, Kritchevsky S, Liu Y, London S, Niu L, Wilson RS, De Jager PL, Yu L, Singleton AB, Harris T, Mosley TH, Pinto JM, Bennett DA, Chen H. Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults. Medicine (Baltimore). 2015 Nov; 94(47):e1892. PMID: 26632684.
      View in: PubMed
    239. Buchman AS, Yu L, Wilson RS, Dawe RJ, VanderHorst V, Schneider JA, Bennett DA. Post-mortem brain pathology is related to declining respiratory function in community-dwelling older adults. Front Aging Neurosci. 2015; 7:197. PMID: 26539108.
      View in: PubMed
    240. Schneider JA, Yu L, Bennett DA. Author Response. Neurology. 2015 Oct 13; 85(15):1355. PMID: 26744756.
      View in: PubMed
    241. Dickson DW, Rademakers R, Nicholson AM, Schneider JA, Yu L, Bennett DA. The TMEM106B locus and TDP-43 pathology in older persons without FTLD. Neurology. 2015 Oct 13; 85(15):1354-5. PMID: 26459943.
      View in: PubMed
    242. Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, Teumer A, Ehret GB, Ferreira T, Heard-Costa NL, Karjalainen J, Lagou V, Mahajan A, Neinast MD, Prokopenko I, Simino J, Teslovich TM, Jansen R, Westra HJ, White CC, Absher D, Ahluwalia TS, Ahmad S, Albrecht E, Alves AC, Bragg-Gresham JL, de Craen AJ, Bis JC, Bonnefond A, Boucher G, Cadby G, Cheng YC, Chiang CW, Delgado G, Demirkan A, Dueker N, Eklund N, Eiriksdottir G, Eriksson J, Feenstra B, Fischer K, Frau F, Galesloot TE, Geller F, Goel A, Gorski M, Grammer TB, Gustafsson S, Haitjema S, Hottenga JJ, Huffman JE, Jackson AU, Jacobs KB, Johansson Å, Kaakinen M, Kleber ME, Lahti J, Mateo Leach I, Lehne B, Liu Y, Lo KS, Lorentzon M, Luan J, Madden PA, Mangino M, McKnight B, Medina-Gomez C, Monda KL, Montasser ME, Müller G, Müller-Nurasyid M, Nolte IM, Panoutsopoulou K, Pascoe L, Paternoster L, Rayner NW, Renström F, Rizzi F, Rose LM, Ryan KA, Salo P, Sanna S, Scharnagl H, Shi J, Smith AV, Southam L, Stancáková A, Steinthorsdottir V, Strawbridge RJ, Sung YJ, Tachmazidou I, Tanaka T, Thorleifsson G, Trompet S, Pervjakova N, Tyrer JP, Vandenput L, van der Laan SW, van der Velde N, van Setten J, van Vliet-Ostaptchouk JV, Verweij N, Vlachopoulou E, Waite LL, Wang SR, Wang Z, Wild SH, Willenborg C, Wilson JF, Wong A, Yang J, Yengo L, Yerges-Armstrong LM, Yu L, Zhang W, Zhao JH, Andersson EA, Bakker SJ, Baldassarre D, Banasik K, Barcella M, Barlassina C, Bellis C, Benaglio P, Blangero J, Blüher M, Bonnet F, Bonnycastle LL, Boyd HA, Bruinenberg M, Buchman AS, Campbell H, Chen YD, Chines PS, Claudi-Boehm S, Cole J, Collins FS, de Geus EJ, de Groot LC, Dimitriou M, Duan J, Enroth S, Eury E, Farmaki AE, Forouhi NG, Friedrich N, Gejman PV, Gigante B, Glorioso N, Go AS, Gottesman O, Gräßler J, Grallert H, Grarup N, Gu YM, Broer L, Ham AC, Hansen T, Harris TB, Hartman CA, Hassinen M, Hastie N, Hattersley AT, Heath AC, Henders AK, Hernandez D, Hillege H, Holmen O, Hovingh KG, Hui J, Husemoen LL, Hutri-Kähönen N, Hysi PG, Illig T, De Jager PL, Jalilzadeh S, Jørgensen T, Jukema JW, Juonala M, Kanoni S, Karaleftheri M, Khaw KT, Kinnunen L, Kittner SJ, Koenig W, Kolcic I, Kovacs P, Krarup NT, Kratzer W, Krüger J, Kuh D, Kumari M, Kyriakou T, Langenberg C, Lannfelt L, Lanzani C, Lotay V, Launer LJ, Leander K, Lindström J, Linneberg A, Liu YP, Lobbens S, Luben R, Lyssenko V, Männistö S, Magnusson PK, McArdle WL, Menni C, Merger S, Milani L, Montgomery GW, Morris AP, Narisu N, Nelis M, Ong KK, Palotie A, Pérusse L, Pichler I, Pilia MG, Pouta A, Rheinberger M, Ribel-Madsen R, Richards M, Rice KM, Rice TK, Rivolta C, Salomaa V, Sanders AR, Sarzynski MA, Scholtens S, Scott RA, Scott WR, Sebert S, Sengupta S, Sennblad B, Seufferlein T, Silveira A, Slagboom PE, Smit JH, Sparsø TH, Stirrups K, Stolk RP, Stringham HM, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Thorand B, Tönjes A, Tremblay A, Tsafantakis E, van der Most PJ, Völker U, Vohl MC, Vonk JM, Waldenberger M, Walker RW, Wennauer R, Widén E, Willemsen G, Wilsgaard T, Wright AF, Zillikens MC, van Dijk SC, van Schoor NM, Asselbergs FW, de Bakker PI, Beckmann JS, Beilby J, Bennett DA, Bergman RN, Bergmann S, Böger CA, Boehm BO, Boerwinkle E, Boomsma DI, Bornstein SR, Bottinger EP, Bouchard C, Chambers JC, Chanock SJ, Chasman DI, Cucca F, Cusi D, Dedoussis G, Erdmann J, Eriksson JG, Evans DA, de Faire U, Farrall M, Ferrucci L, Ford I, Franke L, Franks PW, Froguel P, Gansevoort RT, Gieger C, Grönberg H, Gudnason V, Gyllensten U, Hall P, Hamsten A, van der Harst P, Hayward C, Heliövaara M, Hengstenberg C, Hicks AA, Hingorani A, Hofman A, Hu F, Huikuri HV, Hveem K, James AL, Jordan JM, Jula A, Kähönen M, Kajantie E, Kathiresan S, Kiemeney LA, Kivimaki M, Knekt PB, Koistinen HA, Kooner JS, Koskinen S, Kuusisto J, Maerz W, Martin NG, Laakso M, Lakka TA, Lehtimäki T, Lettre G, Levinson DF, Lind L, Lokki ML, Mäntyselkä P, Melbye M, Metspalu A, et al. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet. 2015 Oct; 11(10):e1005378. PMID: 26426971.
      View in: PubMed
    243. Farfel JM, Yu L, De Jager PL, Schneider JA, Bennett DA. Association of APOE with tau-tangle pathology with and without ß-amyloid. Neurobiol Aging. 2016 Jan; 37:19-25. PMID: 26481403.
      View in: PubMed
    244. Wilson RS, Boyle PA, Yu L, Barnes LL, Sytsma J, Buchman AS, Bennett DA, Schneider JA. Temporal course and pathologic basis of unawareness of memory loss in dementia. Neurology. 2015 Sep 15; 85(11):984-91. PMID: 26311746.
      View in: PubMed
    245. Yu L, Boyle PA, Nag S, Leurgans S, Buchman AS, Wilson RS, Arvanitakis Z, Farfel JM, De Jager PL, Bennett DA, Schneider JA. APOE and cerebral amyloid angiopathy in community-dwelling older persons. Neurobiol Aging. 2015 Nov; 36(11):2946-2953. PMID: 26341746.
      View in: PubMed
    246. Sohail S, Yu L, Bennett DA, Buchman AS, Lim AS. Irregular 24-hour activity rhythms and the metabolic syndrome in older adults. Chronobiol Int. 2015; 32(6):802-13. PMID: 26061588.
      View in: PubMed
    247. Yang J, Yu L, Gaiteri C, Srivastava GP, Chibnik LB, Leurgans SE, Schneider JA, Meissner A, De Jager PL, Bennett DA. Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies. Int J Biochem Cell Biol. 2015 Oct; 67:58-64. PMID: 26003740.
      View in: PubMed
    248. Han SD, Boyle PA, James BD, Yu L, Barnes LL, Bennett DA. Discrepancies between cognition and decision making in older adults. Aging Clin Exp Res. 2016 Feb; 28(1):99-108. PMID: 25995167.
      View in: PubMed
    249. Chibnik LB, Yu L, Eaton ML, Srivastava G, Schneider JA, Kellis M, Bennett DA, De Jager PL. Alzheimer's loci: epigenetic associations and interaction with genetic factors. Ann Clin Transl Neurol. 2015 Jun; 2(6):636-47. PMID: 26125039.
      View in: PubMed
    250. Yu L, Boyle PA, Leurgans S, Schneider JA, Kryscio RJ, Wilson RS, Bennett DA. Effect of common neuropathologies on progression of late life cognitive impairment. Neurobiol Aging. 2015 Jul; 36(7):2225-2231. PMID: 25976345.
      View in: PubMed
    251. Nag S, Yu L, Capuano AW, Wilson RS, Leurgans SE, Bennett DA, Schneider JA. Hippocampal sclerosis and TDP-43 pathology in aging and Alzheimer disease. Ann Neurol. 2015 Jun; 77(6):942-52. PMID: 25707479.
      View in: PubMed
    252. Han SD, Boyle PA, James BD, Yu L, Bennett DA. Poorer Financial and Health Literacy Among Community-Dwelling Older Adults With Mild Cognitive Impairment. J Aging Health. 2015 Sep; 27(6):1105-17. PMID: 25903976.
      View in: PubMed
    253. Han SD, Boyle PA, James BD, Yu L, Bennett DA. Mild cognitive impairment is associated with poorer decision-making in community-based older persons. J Am Geriatr Soc. 2015 Apr; 63(4):676-83. PMID: 25850350.
      View in: PubMed
    254. James BD, Boyle PA, Yu L, Han SD, Bennett DA. Cognitive decline is associated with risk aversion and temporal discounting in older adults without dementia. PLoS One. 2015; 10(4):e0121900. PMID: 25838074.
      View in: PubMed
    255. Yu L, Boyle PA, Wilson RS, Levine SR, Schneider JA, Bennett DA. Purpose in life and cerebral infarcts in community-dwelling older people. Stroke. 2015 Apr; 46(4):1071-6. PMID: 25791714.
      View in: PubMed
    256. Zhao PW, Ma L, Ji HF, Yu L, Feng JY, Wang J, Liu MY, Jiang YF. The expression of TLR-9, CD86, and CD95 phenotypes in circulating B cells of patients with chronic viral hepatitis B or C before and after antiviral therapy. Mediators Inflamm. 2015; 2015:762709. PMID: 25892855.
      View in: PubMed
    257. Wilson RS, Boyle PA, Yu L, Segawa E, Sytsma J, Bennett DA. Conscientiousness, dementia related pathology, and trajectories of cognitive aging. Psychol Aging. 2015 Mar; 30(1):74-82. PMID: 25664558.
      View in: PubMed
    258. Yu L, De Jager PL, Yang J, Trojanowski JQ, Bennett DA, Schneider JA. The TMEM106B locus and TDP-43 pathology in older persons without FTLD. Neurology. 2015 Mar 03; 84(9):927-34. PMID: 25653292.
      View in: PubMed
    259. Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. JAMA Neurol. 2015 Feb; 72(2):209-16. PMID: 25531812.
      View in: PubMed
    260. Yokoyama JS, Sturm VE, Bonham LW, Klein E, Arfanakis K, Yu L, Coppola G, Kramer JH, Bennett DA, Miller BL, Dubal DB. Variation in longevity gene KLOTHO is associated with greater cortical volumes. Ann Clin Transl Neurol. 2015 Mar; 2(3):215-30. PMID: 25815349.
      View in: PubMed
    261. Chauhan G, Adams HHH, Bis JC, Weinstein G, Yu L, Töglhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, Phan TG, Beare RJ, Arfanakis K, Fleischman D, Vernooij MW, Mazoyer B, Schmidt H, Srikanth V, Knopman DS, Jack CR, Amouyel P, Hofman A, DeCarli C, Tzourio C, van Duijn CM, Bennett DA, Schmidt R, Longstreth WT, Mosley TH, Fornage M, Launer LJ, Seshadri S, Ikram MA, Debette S. Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. Neurobiol Aging. 2015 Apr; 36(4):1765.e7-1765.e16. PMID: 25670335.
      View in: PubMed
    262. Nadimpalli SB, James BD, Yu L, Cothran F, Barnes LL. The association between discrimination and depressive symptoms among older African Americans: the role of psychological and social factors. Exp Aging Res. 2015; 41(1):1-24. PMID: 25494668.
      View in: PubMed
    263. Yu L, Chibnik LB, Srivastava GP, Pochet N, Yang J, Xu J, Kozubek J, Obholzer N, Leurgans SE, Schneider JA, Meissner A, De Jager PL, Bennett DA. Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease. JAMA Neurol. 2015 Jan; 72(1):15-24. PMID: 25365775.
      View in: PubMed
    264. Bihlmeyer NA, Brody JA, Smith AV, Lunetta KL, Nalls M, Smith JA, Tanaka T, Davies G, Yu L, Mirza SS, Teumer A, Coresh J, Pankow JS, Franceschini N, Scaria A, Oshima J, Psaty BM, Gudnason V, Eiriksdottir G, Harris TB, Li H, Karasik D, Kiel DP, Garcia M, Liu Y, Faul JD, Kardia SL, Zhao W, Ferrucci L, Allerhand M, Liewald DC, Redmond P, Starr JM, De Jager PL, Evans DA, Direk N, Ikram MA, Uitterlinden A, Homuth G, Lorbeer R, Grabe HJ, Launer L, Murabito JM, Singleton AB, Weir DR, Bandinelli S, Deary IJ, Bennett DA, Tiemeier H, Kocher T, Lumley T, Arking DE. Genetic diversity is a predictor of mortality in humans. BMC Genet. 2014 Dec 29; 15:159. PMID: 25543667.
      View in: PubMed
    265. Yu L, Boyle PA, Segawa E, Leurgans S, Schneider JA, Wilson RS, Bennett DA. Residual decline in cognition after adjustment for common neuropathologic conditions. Neuropsychology. 2015 May; 29(3):335-43. PMID: 25495832.
      View in: PubMed
    266. Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, Davies G, Wolf C, Gudnason V, Chibnik LB, Yang Q, deStefano AL, de Quervain DJ, Srikanth V, Lahti J, Grabe HJ, Smith JA, Priebe L, Yu L, Karbalai N, Hayward C, Wilson JF, Campbell H, Petrovic K, Fornage M, Chauhan G, Yeo R, Boxall R, Becker J, Stegle O, Mather KA, Chouraki V, Sun Q, Rose LM, Resnick S, Oldmeadow C, Kirin M, Wright AF, Jonsdottir MK, Au R, Becker A, Amin N, Nalls MA, Turner ST, Kardia SL, Oostra B, Windham G, Coker LH, Zhao W, Knopman DS, Heiss G, Griswold ME, Gottesman RF, Vitart V, Hastie ND, Zgaga L, Rudan I, Polasek O, Holliday EG, Schofield P, Choi SH, Tanaka T, An Y, Perry RT, Kennedy RE, Sale MM, Wang J, Wadley VG, Liewald DC, Ridker PM, Gow AJ, Pattie A, Starr JM, Porteous D, Liu X, Thomson R, Armstrong NJ, Eiriksdottir G, Assareh AA, Kochan NA, Widen E, Palotie A, Hsieh YC, Eriksson JG, Vogler C, van Swieten JC, Shulman JM, Beiser A, Rotter J, Schmidt CO, Hoffmann W, Nöthen MM, Ferrucci L, Attia J, Uitterlinden AG, Amouyel P, Dartigues JF, Amieva H, Räikkönen K, Garcia M, Wolf PA, Hofman A, Longstreth WT, Psaty BM, Boerwinkle E, DeJager PL, Sachdev PS, Schmidt R, Breteler MM, Teumer A, Lopez OL, Cichon S, Chasman DI, Grodstein F, Müller-Myhsok B, Tzourio C, Papassotiropoulos A, Bennett DA, Ikram MA, Deary IJ, van Duijn CM, Launer L, Fitzpatrick AL, Seshadri S, Mosley TH. Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biol Psychiatry. 2015 Apr 15; 77(8):749-63. PMID: 25648963.
      View in: PubMed
    267. Lim AS, Srivastava GP, Yu L, Chibnik LB, Xu J, Buchman AS, Schneider JA, Myers AJ, Bennett DA, De Jager PL. 24-hour rhythms of DNA methylation and their relation with rhythms of RNA expression in the human dorsolateral prefrontal cortex. PLoS Genet. 2014 Nov; 10(11):e1004792. PMID: 25375876.
      View in: PubMed
    268. Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404. PMID: 25199842.
      View in: PubMed
    269. Gamble K, Boyle P, Yu L, Bennett D. Aging and Financial Decision Making. Manage Sci. 2015 Nov; 61(11):2603-2610. PMID: 26622068.
      View in: PubMed
    270. Arvanitakis Z, Brey RL, Rand JH, Schneider JA, Capuano AW, Yu L, Leurgans SE, Bennett DA, Levine SR. Relation of antiphospholipid antibodies to postmortem brain infarcts in older people. Circulation. 2015 Jan 13; 131(2):182-9. PMID: 25301832.
      View in: PubMed
    271. Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, Eirkisdottir G, Evans DA, Garcia ME, Hofman A, Kaplan RC, Kardia SL, Kiel DP, Oostra BA, Orwoll ES, Parimi N, Psaty BM, Rivadeneira F, Rotter JI, Seshadri S, Singleton A, Tiemeier H, Uitterlinden AG, Zhao W, Bandinelli S, Bennett DA, Ferrucci L, Gudnason V, Harris TB, Karasik D, Launer LJ, Perls TT, Slagboom PE, Tranah GJ, Weir DR, Newman AB, van Duijn CM, Murabito JM. GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. J Gerontol A Biol Sci Med Sci. 2015 Jan; 70(1):110-8. PMID: 25199915.
      View in: PubMed
    272. Lim AS, Ellison BA, Wang JL, Yu L, Schneider JA, Buchman AS, Bennett DA, Saper CB. Sleep is related to neuron numbers in the ventrolateral preoptic/intermediate nucleus in older adults with and without Alzheimer's disease. Brain. 2014 Oct; 137(Pt 10):2847-61. PMID: 25142380.
      View in: PubMed
    273. Buchman AS, Yu L, Wilson RS, Boyle PA, Schneider JA, Bennett DA. Brain pathology contributes to simultaneous change in physical frailty and cognition in old age. J Gerontol A Biol Sci Med Sci. 2014 Dec; 69(12):1536-44. PMID: 25136002.
      View in: PubMed
    274. De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, Chai HS, Younkin C, Younkin SG, Zou F, Szyf M, Epstein CB, Schneider JA, Bernstein BE, Meissner A, Ertekin-Taner N, Chibnik LB, Kellis M, Mill J, Bennett DA. Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci. Nat Neurosci. 2014 Sep; 17(9):1156-63. PMID: 25129075.
      View in: PubMed
    275. Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Denning N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Schmidt H, Kunkle B, Dunstan ML, Vronskaya M. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. PLoS One. 2014; 9(6):e94661. PMID: 24922517.
      View in: PubMed
    276. Han SD, Boyle PA, Yu L, Fleischman DA, Arfanakis K, Leurgans S, Bennett DA. Financial literacy is associated with medial brain region functional connectivity in old age. Arch Gerontol Geriatr. 2014 Sep-Oct; 59(2):429-38. PMID: 24893911.
      View in: PubMed
    277. Bennett DA, Yu L, Yang J, Srivastava GP, Aubin C, De Jager PL. Epigenomics of Alzheimer's disease. Transl Res. 2015 Jan; 165(1):200-20. PMID: 24905038.
      View in: PubMed
    278. Dubal DB, Yokoyama JS, Zhu L, Broestl L, Worden K, Wang D, Sturm VE, Kim D, Klein E, Yu GQ, Ho K, Eilertson KE, Yu L, Kuro-o M, De Jager PL, Coppola G, Small GW, Bennett DA, Kramer JH, Abraham CR, Miller BL, Mucke L. Life extension factor klotho enhances cognition. Cell Rep. 2014 May 22; 7(4):1065-76. PMID: 24813892.
      View in: PubMed
    279. Buchman AS, Yu L, Wilson RS, Shulman JM, Boyle PA, Bennett DA. Harm avoidance is associated with progression of parkinsonism in community-dwelling older adults: a prospective cohort study. BMC Geriatr. 2014 Apr 23; 14:54. PMID: 24754876.
      View in: PubMed
    280. Shulman JM, Yu L, Buchman AS, Evans DA, Schneider JA, Bennett DA, De Jager PL. Association of Parkinson disease risk loci with mild parkinsonian signs in older persons. JAMA Neurol. 2014 Apr; 71(4):429-35. PMID: 24514572.
      View in: PubMed
    281. Bennett DA, Yu L, De Jager PL. Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease. Biochem Pharmacol. 2014 Apr 15; 88(4):617-30. PMID: 24508835.
      View in: PubMed
    282. Wilson RS, Boyle PA, Levine SR, Yu L, Hoganson GM, Buchman AS, Schneider JA, Bennett DA. Harm avoidance and cerebral infarction. Neuropsychology. 2014 Mar; 28(2):305-11. PMID: 24364391.
      View in: PubMed
    283. Lim AS, Yu L, Kowgier M, Schneider JA, Buchman AS, Bennett DA. Modification of the relationship of the apolipoprotein E e4 allele to the risk of Alzheimer disease and neurofibrillary tangle density by sleep. JAMA Neurol. 2013 Dec; 70(12):1544-51. PMID: 24145819.
      View in: PubMed
    284. Wilson RS, Nag S, Boyle PA, Hizel LP, Yu L, Buchman AS, Shah RC, Schneider JA, Arnold SE, Bennett DA. Brainstem aminergic nuclei and late-life depressive symptoms. JAMA Psychiatry. 2013 Dec; 70(12):1320-8. PMID: 24132763.
      View in: PubMed
    285. Wilson RS, Yu L, Trojanowski JQ, Chen EY, Boyle PA, Bennett DA, Schneider JA. TDP-43 pathology, cognitive decline, and dementia in old age. JAMA Neurol. 2013 Nov; 70(11):1418-24. PMID: 24080705.
      View in: PubMed
    286. Han SD, Boyle PA, Yu L, Fleischman DA, Arfanakis K, Bennett DA. Ventromedial PFC, parahippocampal, and cerebellar connectivity are associated with temporal discounting in old age. Exp Gerontol. 2013 Dec; 48(12):1489-98. PMID: 24135750.
      View in: PubMed
    287. Yu L, Boyle PA, Leurgans S, Schneider JA, Bennett DA. Disentangling the effects of age and APOE on neuropathology and late life cognitive decline. Neurobiol Aging. 2014 Apr; 35(4):819-26. PMID: 24199961.
      View in: PubMed
    288. James BD, Boyle PA, Yu L, Bennett DA. Internet use and decision making in community-based older adults. Front Psychol. 2013; 4:605. PMID: 24578696.
      View in: PubMed
    289. Boyle PA, Yu L, Wilson RS, Schneider JA, Bennett DA. Relation of neuropathology with cognitive decline among older persons without dementia. Front Aging Neurosci. 2013; 5:50. PMID: 24058343.
      View in: PubMed
    290. Shulman JM, Chen K, Keenan BT, Chibnik LB, Fleisher A, Thiyyagura P, Roontiva A, McCabe C, Patsopoulos NA, Corneveaux JJ, Yu L, Huentelman MJ, Evans DA, Schneider JA, Reiman EM, De Jager PL, Bennett DA. Genetic susceptibility for Alzheimer disease neuritic plaque pathology. JAMA Neurol. 2013 Sep 01; 70(9):1150-7. PMID: 23836404.
      View in: PubMed
    291. Boyle PA, Yu L, Wilson RS, Segawa E, Buchman AS, Bennett DA. Cognitive decline impairs financial and health literacy among community-based older persons without dementia. Psychol Aging. 2013 Sep; 28(3):614-24. PMID: 23957225.
      View in: PubMed
    292. Buchman AS, Wilson RS, Yu L, James BD, Boyle PA, Bennett DA. Total daily activity declines more rapidly with increasing age in older adults. Arch Gerontol Geriatr. 2014 Jan-Feb; 58(1):74-9. PMID: 24007938.
      View in: PubMed
    293. Wu G, Zhang B, Yu C, Gao L, Gao Y, Huang Y, Yu L, Zhang G, Yang L, Yuan J. Effect of early adrenal vein ligation on blood pressure and catecholeamine fluctuation during laparoscopic adrenalectomy for pheochromocytoma. Urology. 2013 Sep; 82(3):606-11. PMID: 23859530.
      View in: PubMed
    294. Boyle PA, Wilson RS, Yu L, Barr AM, Honer WG, Schneider JA, Bennett DA. Much of late life cognitive decline is not due to common neurodegenerative pathologies. Ann Neurol. 2013 Sep; 74(3):478-89. PMID: 23798485.
      View in: PubMed
    295. Wilson RS, Boyle PA, Yu L, Barnes LL, Schneider JA, Bennett DA. Life-span cognitive activity, neuropathologic burden, and cognitive aging. Neurology. 2013 Jul 23; 81(4):314-21. PMID: 23825173.
      View in: PubMed
    296. Lim AS, Kowgier M, Yu L, Buchman AS, Bennett DA. Sleep Fragmentation and the Risk of Incident Alzheimer's Disease and Cognitive Decline in Older Persons. Sleep. 2013 Jul 01; 36(7):1027-1032. PMID: 23814339.
      View in: PubMed
    297. Boyle PA, Yu L, Gamble KJ, Bennett DA. Temporal Discounting Is Associated with an Increased Risk of Mortality among Community-Based Older Persons without Dementia. PLoS One. 2013; 8(6):e67376. PMID: 23826281.
      View in: PubMed
    298. Fleischman DA, Yu L, Arfanakis K, Han SD, Barnes LL, Arvanitakis Z, Boyle PA, Bennett DA. Faster cognitive decline in the years prior to MR imaging is associated with smaller hippocampal volumes in cognitively healthy older persons. Front Aging Neurosci. 2013; 5:21. PMID: 23760360.
      View in: PubMed
    299. Shah RC, Janos AL, Kline JE, Yu L, Leurgans SE, Wilson RS, Wei P, Bennett DA, Heilman KM, Tsao JW. Cognitive decline in older persons initiating anticholinergic medications. PLoS One. 2013; 8(5):e64111. PMID: 23741303.
      View in: PubMed
    300. Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra HJ, Shakhbazov K, Abdellaoui A, Agrawal A, Albrecht E, Alizadeh BZ, Amin N, Barnard J, Baumeister SE, Benke KS, Bielak LF, Boatman JA, Boyle PA, Davies G, de Leeuw C, Eklund N, Evans DS, Ferhmann R, Fischer K, Gieger C, Gjessing HK, Hägg S, Harris JR, Hayward C, Holzapfel C, Ibrahim-Verbaas CA, Ingelsson E, Jacobsson B, Joshi PK, Jugessur A, Kaakinen M, Kanoni S, Karjalainen J, Kolcic I, Kristiansson K, Kutalik Z, Lahti J, Lee SH, Lin P, Lind PA, Liu Y, Lohman K, Loitfelder M, McMahon G, Vidal PM, Meirelles O, Milani L, Myhre R, Nuotio ML, Oldmeadow CJ, Petrovic KE, Peyrot WJ, Polasek O, Quaye L, Reinmaa E, Rice JP, Rizzi TS, Schmidt H, Schmidt R, Smith AV, Smith JA, Tanaka T, Terracciano A, van der Loos MJ, Vitart V, Völzke H, Wellmann J, Yu L, Zhao W, Allik J, Attia JR, Bandinelli S, Bastardot F, Beauchamp J, Bennett DA, Berger K, Bierut LJ, Boomsma DI, Bültmann U, Campbell H, Chabris CF, Cherkas L, Chung MK, Cucca F, de Andrade M, De Jager PL, De Neve JE, Deary IJ, Dedoussis GV, Deloukas P, Dimitriou M, Eiríksdóttir G, Elderson MF, Eriksson JG, Evans DM, Faul JD, Ferrucci L, Garcia ME, Grönberg H, Guðnason V, Hall P, Harris JM, Harris TB, Hastie ND, Heath AC, Hernandez DG, Hoffmann W, Hofman A, Holle R, Holliday EG, Hottenga JJ, Iacono WG, Illig T, Järvelin MR, Kähönen M, Kaprio J, Kirkpatrick RM, Kowgier M, Latvala A, Launer LJ, Lawlor DA, Lehtimäki T, Li J, Lichtenstein P, Lichtner P, Liewald DC, Madden PA, Magnusson PK, Mäkinen TE, Masala M, McGue M, Metspalu A, Mielck A, Miller MB, Montgomery GW, Mukherjee S, Nyholt DR, Oostra BA, Palmer LJ, Palotie A, Penninx BW, Perola M, Peyser PA, Preisig M, Räikkönen K, Raitakari OT, Realo A, Ring SM, Ripatti S, Rivadeneira F, Rudan I, Rustichini A, Salomaa V, Sarin AP, Schlessinger D, Scott RJ, Snieder H, St Pourcain B, Starr JM, Sul JH, Surakka I, Svento R, Teumer A. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science. 2013 Jun 21; 340(6139):1467-71. PMID: 23722424.
      View in: PubMed
    301. Yu L, Boyle P, Schneider JA, Segawa E, Wilson RS, Leurgans S, Bennett DA. APOE e4, Alzheimer's disease pathology, cerebrovascular disease, and cognitive change over the years prior to death. Psychol Aging. 2013 Dec; 28(4):1015-23. PMID: 23647000.
      View in: PubMed
    302. Buchman AS, Yu L, Wilson RS, Schneider JA, Bennett DA. Association of brain pathology with the progression of frailty in older adults. Neurology. 2013 May 28; 80(22):2055-61. PMID: 23635961.
      View in: PubMed
    303. Lim AS, Myers AJ, Yu L, Buchman AS, Duffy JF, De Jager PL, Bennett DA. Sex difference in daily rhythms of clock gene expression in the aged human cerebral cortex. J Biol Rhythms. 2013 Apr; 28(2):117-29. PMID: 23606611.
      View in: PubMed
    304. Wilson RS, Nag S, Boyle PA, Hizel LP, Yu L, Buchman AS, Schneider JA, Bennett DA. Neural reserve, neuronal density in the locus ceruleus, and cognitive decline. Neurology. 2013 Mar 26; 80(13):1202-8. PMID: 23486878.
      View in: PubMed
    305. Kotrotsou A, Bennett DA, Schneider JA, Dawe RJ, Golak T, Leurgans SE, Yu L, Arfanakis K. Ex vivo MR volumetry of human brain hemispheres. Magn Reson Med. 2014 Jan; 71(1):364-74. PMID: 23440751.
      View in: PubMed
    306. Wilson RS, Boyle PA, Segawa E, Yu L, Begeny CT, Anagnos SE, Bennett DA. The influence of cognitive decline on well-being in old age. Psychol Aging. 2013 Jun; 28(2):304-13. PMID: 23421323.
      View in: PubMed
    307. Buchman AS, Yu L, Boyle PA, Levine SR, Nag S, Schneider JA, Bennett DA. Microvascular brain pathology and late-life motor impairment. Neurology. 2013 Feb 19; 80(8):712-8. PMID: 23365057.
      View in: PubMed
    308. Boyle PA, Wilson RS, Yu L, Buchman AS, Bennett DA. Poor decision making is associated with an increased risk of mortality among community-dwelling older persons without dementia. Neuroepidemiology. 2013; 40(4):247-52. PMID: 23364306.
      View in: PubMed
    309. Ertekin-Taner N, De Jager PL, Yu L, Bennett DA. Alternative Approaches in Gene Discovery and Characterization in Alzheimer's Disease. Curr Genet Med Rep. 2013 Mar; 1(1):39-51. PMID: 23482655.
      View in: PubMed
    310. Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, Liu Y, Marciante K, Meirelles O, Nalls MA, Sun YV, Vogelzangs N, Yu L, Bandinelli S, Benjamin EJ, Bennett DA, Boomsma D, Cannas A, Coker LH, de Geus E, De Jager PL, Diez-Roux AV, Purcell S, Hu FB, Rimma EB, Hunter DJ, Jensen MK, Curhan G, Rice K, Penman AD, Rotter JI, Sotoodehnia N, Emeny R, Eriksson JG, Evans DA, Ferrucci L, Fornage M, Gudnason V, Hofman A, Illig T, Kardia S, Kelly-Hayes M, Koenen K, Kraft P, Kuningas M, Massaro JM, Melzer D, Mulas A, Mulder CL, Murray A, Oostra BA, Palotie A, Penninx B, Petersmann A, Pilling LC, Psaty B, Rawal R, Reiman EM, Schulz A, Shulman JM, Singleton AB, Smith AV, Sutin AR, Uitterlinden AG, Völzke H, Widen E, Yaffe K, Zonderman AB, Cucca F, Harris T, Ladwig KH, Llewellyn DJ, Räikkönen K, Tanaka T, van Duijn CM, Grabe HJ, Launer LJ, Lunetta KL, Mosley TH, Newman AB, Tiemeier H, Murabito J. A genome-wide association study of depressive symptoms. Biol Psychiatry. 2013 Apr 01; 73(7):667-78. PMID: 23290196.
      View in: PubMed
    311. Arvanitakis Z, Brey RL, Rand JH, Schneider JA, Leurgans SE, Yu L, Buchman AS, Arfanakis K, Fleischman DA, Boyle PA, Bennett DA, Levine SR. Antiphospholipid antibodies, brain infarcts, and cognitive and motor decline in aging (ABICMA): design of a community-based, longitudinal, clinical-pathological study. Neuroepidemiology. 2013; 40(2):73-84. PMID: 23095514.
      View in: PubMed
    312. Wilson RS, Boyle PA, Levine SR, Yu L, Anagnos SE, Buchman AS, Schneider JA, Bennett DA. Emotional neglect in childhood and cerebral infarction in older age. Neurology. 2012 Oct 09; 79(15):1534-9. PMID: 22993291.
      View in: PubMed
    313. Boyle PA, Yu L, Segawa E, Wilson RS, Buchman AS, Laibson DI, Bennett DA. Association of cognition with temporal discounting in community based older persons. BMC Geriatr. 2012 Aug 31; 12:48. PMID: 22938391.
      View in: PubMed
    314. Boyle PA, Yu L, Wilson RS, Gamble K, Buchman AS, Bennett DA. Poor decision making is a consequence of cognitive decline among older persons without Alzheimer's disease or mild cognitive impairment. PLoS One. 2012; 7(8):e43647. PMID: 22916287.
      View in: PubMed
    315. Yu L, Boyle P, Wilson RS, Segawa E, Leurgans S, De Jager PL, Bennett DA. A random change point model for cognitive decline in Alzheimer's disease and mild cognitive impairment. Neuroepidemiology. 2012; 39(2):73-83. PMID: 22814083.
      View in: PubMed
    316. Boyle PA, Yu L, Buchman AS, Bennett DA. Risk Aversion is Associated with Decision Making among Community-Based Older Persons. Front Psychol. 2012; 3:205. PMID: 22754545.
      View in: PubMed
    317. Boyle PA, Buchman AS, Wilson RS, Yu L, Schneider JA, Bennett DA. Effect of purpose in life on the relation between Alzheimer disease pathologic changes on cognitive function in advanced age. Arch Gen Psychiatry. 2012 May; 69(5):499-505. PMID: 22566582.
      View in: PubMed
    318. Lim AS, Yu L, Costa MD, Leurgans SE, Buchman AS, Bennett DA, Saper CB. Increased fragmentation of rest-activity patterns is associated with a characteristic pattern of cognitive impairment in older individuals. Sleep. 2012 May 01; 35(5):633-40B. PMID: 22547889.
      View in: PubMed
    319. Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012 Apr 15; 44(5):545-51. PMID: 22504421.
      View in: PubMed
    320. Buchman AS, Yu L, Boyle PA, Shah RC, Bennett DA. Total daily physical activity and longevity in old age. Arch Intern Med. 2012 Mar 12; 172(5):444-6. PMID: 22412115.
      View in: PubMed
    321. Yu L, Shulman JM, Chibnik L, Leurgans S, Schneider JA, De Jager PL, Bennett DA. The CETP I405V polymorphism is associated with an increased risk of Alzheimer's disease. Aging Cell. 2012 Apr; 11(2):228-33. PMID: 22122979.
      View in: PubMed
    322. De Jager PL, Shulman JM, Chibnik LB, Keenan BT, Raj T, Wilson RS, Yu L, Leurgans SE, Tran D, Aubin C, Anderson CD, Biffi A, Corneveaux JJ, Huentelman MJ. A genome-wide scan for common variants affecting the rate of age-related cognitive decline. Neurobiol Aging. 2012 May; 33(5):1017.e1-15. PMID: 22054870.
      View in: PubMed
    323. Lim AS, Yu L, Costa MD, Buchman AS, Bennett DA, Leurgans SE, Saper CB. Quantification of the fragmentation of rest-activity patterns in elderly individuals using a state transition analysis. Sleep. 2011 Nov 01; 34(11):1569-81. PMID: 22043128.
      View in: PubMed
    324. Han SD, Boyle PA, Arfanakis K, Fleischman DA, Yu L, Edmonds EC, Bennett DA. Neural intrinsic connectivity networks associated with risk aversion in old age. Behav Brain Res. 2012 Feb 01; 227(1):233-40. PMID: 22044475.
      View in: PubMed
    325. Wilson RS, Boyle PA, Buchman AS, Yu L, Arnold SE, Bennett DA. Harm avoidance and risk of Alzheimer's disease. Psychosom Med. 2011 Oct; 73(8):690-6. PMID: 21949425.
      View in: PubMed
    326. Boyle PA, Yu L, Buchman AS, Laibson DI, Bennett DA. Cognitive function is associated with risk aversion in community-based older persons. BMC Geriatr. 2011 Sep 11; 11:53. PMID: 21906402.
      View in: PubMed
    327. Walter S, Atzmon G, Demerath EW, Garcia ME, Kaplan RC, Kumari M, Lunetta KL, Milaneschi Y, Tanaka T, Tranah GJ, Völker U, Yu L, Arnold A, Benjamin EJ, Biffar R, Buchman AS, Boerwinkle E, Couper D, De Jager PL, Evans DA, Harris TB, Hoffmann W, Hofman A, Karasik D, Kiel DP, Kocher T, Kuningas M, Launer LJ, Lohman KK, Lutsey PL, Mackenbach J, Marciante K, Psaty BM, Reiman EM, Rotter JI, Seshadri S, Shardell MD, Smith AV, van Duijn C, Walston J, Zillikens MC, Bandinelli S, Baumeister SE, Bennett DA, Ferrucci L, Gudnason V, Kivimaki M, Liu Y, Murabito JM, Newman AB, Tiemeier H, Franceschini N. A genome-wide association study of aging. Neurobiol Aging. 2011 Nov; 32(11):2109.e15-28. PMID: 21782286.
      View in: PubMed
    328. Gao L, Wu GJ, Liu XW, Zhang R, Yu L, Zhang G, Liu F, Yu CG, Yuan JL, Wang H, Yao LB. Suppression of invasion and metastasis of prostate cancer cells by overexpression of NDRG2 gene. Cancer Lett. 2011 Nov 01; 310(1):94-100. PMID: 21741166.
      View in: PubMed
    329. Wilson RS, Yu L, Schneider JA, Arnold SE, Buchman AS, Bennett DA. Lewy bodies and olfactory dysfunction in old age. Chem Senses. 2011 May; 36(4):367-73. PMID: 21257733.
      View in: PubMed
    330. Wilson RS, Yu L, Bennett DA. Odor identification and mortality in old age. Chem Senses. 2011 Jan; 36(1):63-7. PMID: 20923931.
      View in: PubMed
    331. Yu L, Griffith WS, Tyas SL, Snowdon DA, Kryscio RJ. A nonstationary Markov transition model for computing the relative risk of dementia before death. Stat Med. 2010 Mar 15; 29(6):639-48. PMID: 20087848.
      View in: PubMed
    332. Yu L, Li JY, Wang TY, Ding Y, Zhang YF, Zang N. [Long-term results of esophageal motor dysmotility after Heller's myotomy for achalasia]. Zhonghua Yi Xue Za Zhi. 2010 Jan 05; 90(1):53-5. PMID: 20356527.
      View in: PubMed
    333. Yu L, Tyas SL, Snowdon DA, Kryscio RJ. Effects of ignoring baseline on modeling transitions from intact cognition to dementia. Comput Stat Data Anal. 2009 Jul 01; 53(9):3334-3343. PMID: 20161282.
      View in: PubMed
    334. Yu L, Li JY, Wang TY, Ding Y, Zhang YF, Zang N. [Intraoperative esophageal manometry employed in the course of Heller's cardia-myotomies]. Zhonghua Wai Ke Za Zhi. 2008 Dec 15; 46(24):1916-8. PMID: 19134387.
      View in: PubMed
    335. Yu L, Ma S, Wang TY, Fang JG, Jing Y, Zhang YF, Zang N. [Video-assisted thoracoscopic extended thymectomy for myasthenia gravis]. Zhonghua Wai Ke Za Zhi. 2008 Nov 15; 46(22):1720-2. PMID: 19094733.
      View in: PubMed
    336. Bottiggi KA, Salazar JC, Yu L, Caban-Holt AM, Ryan M, Schmitt FA. Concomitant use of medications with anticholinergic properties and acetylcholinesterase inhibitors: impact on cognitive and physical functioning in Alzheimer disease. Am J Geriatr Psychiatry. 2007 Apr; 15(4):357-9. PMID: 17384320.
      View in: PubMed
    337. Salazar JC, Schmitt FA, Yu L, Mendiondo MM, Kryscio RJ. Shared random effects analysis of multi-state Markov models: application to a longitudinal study of transitions to dementia. Stat Med. 2007 Feb 10; 26(3):568-80. PMID: 16345024.
      View in: PubMed
    338. Bottiggi KA, Salazar JC, Yu L, Caban-Holt AM, Ryan M, Mendiondo MS, Schmitt FA. Long-term cognitive impact of anticholinergic medications in older adults. Am J Geriatr Psychiatry. 2006 Nov; 14(11):980-4. PMID: 17068321.
      View in: PubMed
    339. Xiong SH, Li N, Zhao JM, Yu L, Liao H, Qin TW, Zhong SZ. [Morphological study on three-dimensional culture of rat muscle satellite cells under cyclic mechanical stretch]. Di Yi Jun Yi Da Xue Xue Bao. 2003 Feb; 23(2):141-3. PMID: 12581963.
      View in: PubMed
    Yu's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    See all (788) concept(s)
    _
    Co-Authors Expand Description
    See all (34) people
    _
    Similar People Expand Description
    See all (60) people
    _
    Same Department Expand Description
    Search Department