Isoproterenol
"Isoproterenol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
Descriptor ID |
D007545
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MeSH Number(s) |
D02.033.100.291.439 D02.092.063.291.439 D02.092.311.649
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Concept/Terms |
Isoproterenol- Isoproterenol
- Isoprenaline
- Isopropylnorepinephrine
- Isopropylarterenol
- Isopropylnoradrenaline
- 4-(1-Hydroxy-2-((1-methylethyl)amino)ethyl)-1,2-benzenediol
- Isopropyl Noradrenaline
- Noradrenaline, Isopropyl
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Below are MeSH descriptors whose meaning is more general than "Isoproterenol".
Below are MeSH descriptors whose meaning is more specific than "Isoproterenol".
This graph shows the total number of publications written about "Isoproterenol" by people in this website by year, and whether "Isoproterenol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1990 | 0 | 1 | 1 | 2000 | 0 | 2 | 2 | 2003 | 0 | 1 | 1 | 2005 | 0 | 1 | 1 | 2007 | 1 | 1 | 2 | 2010 | 0 | 2 | 2 | 2011 | 0 | 1 | 1 | 2012 | 0 | 2 | 2 | 2013 | 1 | 0 | 1 | 2014 | 0 | 1 | 1 | 2017 | 0 | 1 | 1 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Isoproterenol" by people in Profiles.
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Hamilton S, Terentyeva R, Bogdanov V, Kim TY, Perger F, Yan J, Ai X, Carnes CA, Belevych AE, George CH, Davis JP, Gyorke S, Choi BR, Terentyev D. Ero1a-Dependent ERp44 Dissociation From RyR2 Contributes to Cardiac Arrhythmia. Circ Res. 2022 03 04; 130(5):711-724.
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Kanaporis G, Treinys R, Fischmeister R, Jurevicius J. Metabolic inhibition reduces cardiac L-type Ca2+ channel current due to acidification caused by ATP hydrolysis. PLoS One. 2017; 12(8):e0184246.
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Seidlmayer LK, Kuhn J, Berbner A, Arias-Loza PA, Williams T, Kaspar M, Czolbe M, Kwong JQ, Molkentin JD, Heinze KG, Dedkova EN, Ritter O. Inositol 1,4,5-trisphosphate-mediated sarcoplasmic reticulum-mitochondrial crosstalk influences adenosine triphosphate production via mitochondrial Ca2+ uptake through the mitochondrial ryanodine receptor in cardiac myocytes. Cardiovasc Res. 2016 10; 112(1):491-501.
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Curran J, Tang L, Roof SR, Velmurugan S, Millard A, Shonts S, Wang H, Santiago D, Ahmad U, Perryman M, Bers DM, Mohler PJ, Ziolo MT, Shannon TR. Nitric oxide-dependent activation of CaMKII increases diastolic sarcoplasmic reticulum calcium release in cardiac myocytes in response to adrenergic stimulation. PLoS One. 2014; 9(2):e87495.
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Santiago DJ, Ríos E, Shannon TR. Isoproterenol increases the fraction of spark-dependent RyR-mediated leak in ventricular myocytes. Biophys J. 2013 Mar 05; 104(5):976-85.
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Domeier TL, Maxwell JT, Blatter LA. ß-Adrenergic stimulation increases the intra-sarcoplasmic reticulum Ca2+ threshold for Ca2+ wave generation. J Physiol. 2012 Dec 01; 590(23):6093-108.
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Ueta CB, Oskouei BN, Olivares EL, Pinto JR, Correa MM, Simovic G, Simonides WS, Hare JM, Bianco AC. Absence of myocardial thyroid hormone inactivating deiodinase results in restrictive cardiomyopathy in mice. Mol Endocrinol. 2012 May; 26(5):809-18.
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Roof SR, Shannon TR, Janssen PM, Ziolo MT. Effects of increased systolic Ca²? and phospholamban phosphorylation during ß-adrenergic stimulation on Ca²? transient kinetics in cardiac myocytes. Am J Physiol Heart Circ Physiol. 2011 Oct; 301(4):H1570-8.
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Nakayama H, Bodi I, Maillet M, DeSantiago J, Domeier TL, Mikoshiba K, Lorenz JN, Blatter LA, Bers DM, Molkentin JD. The IP3 receptor regulates cardiac hypertrophy in response to select stimuli. Circ Res. 2010 Sep 03; 107(5):659-66.
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Curran J, Brown KH, Santiago DJ, Pogwizd S, Bers DM, Shannon TR. Spontaneous Ca waves in ventricular myocytes from failing hearts depend on Ca(2+)-calmodulin-dependent protein kinase II. J Mol Cell Cardiol. 2010 Jul; 49(1):25-32.
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