 Alzheimer Disease
"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Descriptor ID |
D000544
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| MeSH Number(s) |
C10.228.140.380.100 C10.574.945.249 F03.087.400.100
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| Concept/Terms |
Alzheimer Disease- Alzheimer Disease
- Disease, Alzheimer
- Alzheimer Sclerosis
- Sclerosis, Alzheimer
- Alzheimer Syndrome
- Syndrome, Alzheimer
- Alzheimer Type Senile Dementia
- Senile Dementia, Alzheimer Type
- Alzheimer-Type Dementia (ATD)
- Alzheimer Type Dementia (ATD)
- Dementia, Alzheimer-Type (ATD)
- Dementia, Alzheimer Type
- Alzheimer Type Dementia
- Dementia, Primary Senile Degenerative
- Dementia, Senile
- Senile Dementia
- Primary Senile Degenerative Dementia
- Alzheimer Dementia (AD)
- Dementia, Alzheimer (AD)
- Alzheimer's Disease
- Disease, Alzheimer's
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Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".
Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".
This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 1 | 0 | 1 | | 1988 | 2 | 0 | 2 | | 1989 | 1 | 0 | 1 | | 1990 | 2 | 0 | 2 | | 1991 | 3 | 0 | 3 | | 1992 | 2 | 1 | 3 | | 1993 | 1 | 0 | 1 | | 1994 | 3 | 1 | 4 | | 1996 | 0 | 1 | 1 | | 1997 | 7 | 0 | 7 | | 1998 | 5 | 0 | 5 | | 1999 | 8 | 1 | 9 | | 2000 | 13 | 2 | 15 | | 2001 | 5 | 1 | 6 | | 2002 | 16 | 1 | 17 | | 2003 | 22 | 1 | 23 | | 2004 | 22 | 4 | 26 | | 2005 | 35 | 4 | 39 | | 2006 | 20 | 4 | 24 | | 2007 | 19 | 4 | 23 | | 2008 | 16 | 2 | 18 | | 2009 | 17 | 1 | 18 | | 2010 | 21 | 2 | 23 | | 2011 | 32 | 7 | 39 | | 2012 | 32 | 7 | 39 | | 2013 | 25 | 4 | 29 | | 2014 | 42 | 3 | 45 | | 2015 | 36 | 8 | 44 | | 2016 | 28 | 8 | 36 | | 2017 | 31 | 6 | 37 | | 2018 | 52 | 6 | 58 | | 2019 | 43 | 13 | 56 | | 2020 | 25 | 3 | 28 |
To return to the timeline, click here.
Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.
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Sargurupremraj M, Suzuki H, Jian X, Sarnowski C, Evans TE, Bis JC, Eiriksdottir G, Sakaue S, Terzikhan N, Habes M, Zhao W, Armstrong NJ, Hofer E, Yanek LR, Hagenaars SP, Kumar RB, van den Akker EB, McWhirter RE, Trompet S, Mishra A, Saba Y, Satizabal CL, Beaudet G, Petit L, Tsuchida A, Zago L, Schilling S, Sigurdsson S, Gottesman RF, Lewis CE, Aggarwal NT, Lopez OL, Smith JA, Valdés Hernández MC, van der Grond J, Wright MJ, Knol MJ, Dörr M, Thomson RJ, Bordes C, Le Grand Q, Duperron MG, Smith AV, Knopman DS, Schreiner PJ, Evans DA, Rotter JI, Beiser AS, Maniega SM, Beekman M, Trollor J, Stott DJ, Vernooij MW, Wittfeld K, Niessen WJ, Soumaré A, Boerwinkle E, Sidney S, Turner ST, Davies G, Thalamuthu A, Völker U, van Buchem MA, Bryan RN, Dupuis J, Bastin ME, Ames D, Teumer A, Amouyel P, Kwok JB, Bülow R, Deary IJ, Schofield PR, Brodaty H, Jiang J, Tabara Y, Setoh K, Miyamoto S, Yoshida K, Nagata M, Kamatani Y, Matsuda F, Psaty BM, Bennett DA, De Jager PL, Mosley TH, Sachdev PS, Schmidt R, Warren HR, Evangelou E, Trégouët DA. Cerebral small vessel disease genomics and its implications across the lifespan. Nat Commun. 2020 12 08; 11(1):6285.
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Olah M, Menon V, Habib N, Taga MF, Ma Y, Yung CJ, Cimpean M, Khairallah A, Coronas-Samano G, Sankowski R, Grün D, Kroshilina AA, Dionne D, Sarkis RA, Cosgrove GR, Helgager J, Golden JA, Pennell PB, Prinz M, Vonsattel JPG, Teich AF, Schneider JA, Bennett DA, Regev A, Elyaman W, Bradshaw EM, De Jager PL. Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease. Nat Commun. 2020 11 30; 11(1):6129.
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Gicas KM, Honer WG, Wilson RS, Boyle PA, Leurgans SE, Schneider JA, Bennett DA. Association of serial position scores on memory tests and hippocampal-related neuropathologic outcomes. Neurology. 2020 12 15; 95(24):e3303-e3312.
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Rajan KB, Aggarwal NT, McAninch EA, Weuve J, Barnes LL, Wilson RS, DeCarli C, Evans DA. Remote Blood Biomarkers of Longitudinal Cognitive Outcomes in a Population Study. Ann Neurol. 2020 12; 88(6):1065-1076.
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Luningham JM, Chen J, Tang S, De Jager PL, Bennett DA, Buchman AS, Yang J. Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics. Am J Hum Genet. 2020 10 01; 107(4):714-726.
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Bennett DA, Knopman DS. Extending Alzheimer disease biomarker studies into the Hispanic community. Neurology. 2020 10 13; 95(15):665-666.
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Nag S, Barnes LL, Yu L, Wilson RS, Bennett DA, Schneider JA. Limbic-predominant age-related TDP-43 encephalopathy in Black and White decedents. Neurology. 2020 10 13; 95(15):e2056-e2064.
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Kapasi A, Yu L, Boyle PA, Barnes LL, Bennett DA, Schneider JA. Limbic-predominant age-related TDP-43 encephalopathy, ADNC pathology, and cognitive decline in aging. Neurology. 2020 10 06; 95(14):e1951-e1962.
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Dumitrescu L, Mahoney ER, Mukherjee S, Lee ML, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski C, Hernandez Saucedo H, Widaman KF, Buckley R, Properzi M, Mormino E, Yang HS, Harrison T, Hedden T, Nho K, Andrews SJ, Tommet D, Hadad N, Sanders RE, Ruderfer DM, Gifford KA, Moore AM, Cambronero F, Zhong X, Raghavan NS, Vardarajan B. Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Brain. 2020 08 01; 143(8):2561-2575.
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Arvanitakis Z, Wang HY, Capuano AW, Khan A, Taïb B, Anokye-Danso F, Schneider JA, Bennett DA, Ahima RS, Arnold SE. Brain Insulin Signaling, Alzheimer Disease Pathology, and Cognitive Function. Ann Neurol. 2020 09; 88(3):513-525.
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