"Cyclic GMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
Descriptor ID |
D006152
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MeSH Number(s) |
D03.633.100.759.646.454.160 D13.695.462.275 D13.695.667.454.160 D13.695.827.426.160
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Concept/Terms |
Cyclic GMP- Cyclic GMP
- GMP, Cyclic
- Guanosine Cyclic Monophosphate
- Cyclic Monophosphate, Guanosine
- Monophosphate, Guanosine Cyclic
- Guanosine Cyclic 3',5'-Monophosphate
- 3',5'-Monophosphate, Guanosine Cyclic
- Cyclic 3',5'-Monophosphate, Guanosine
- Guanosine Cyclic 3,5 Monophosphate
- Guanosine Cyclic-3',5'-Monophosphate
- Cyclic-3',5'-Monophosphate, Guanosine
- Guanosine Cyclic 3',5' Monophosphate
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Below are MeSH descriptors whose meaning is more general than "Cyclic GMP".
Below are MeSH descriptors whose meaning is more specific than "Cyclic GMP".
This graph shows the total number of publications written about "Cyclic GMP" by people in this website by year, and whether "Cyclic GMP" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2006 | 0 | 3 | 3 |
2009 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclic GMP" by people in Profiles.
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Sildenafil for the Treatment of Congenital Nephrogenic Diabetes Insipidus. Am J Nephrol. 2015; 42(1):65-9.
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Urocortin 2 stimulates nitric oxide production in ventricular myocytes via Akt- and PKA-mediated phosphorylation of eNOS at serine 1177. Am J Physiol Heart Circ Physiol. 2014 Sep 01; 307(5):H689-700.
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Hypoxic depression of PKG-mediated inhibition of serotonergic contraction in ovine carotid arteries. Am J Physiol Regul Integr Comp Physiol. 2013 May 01; 304(9):R734-43.
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Effects of chronic hypoxia on soluble guanylate cyclase activity in fetal and adult ovine cerebral arteries. J Appl Physiol (1985). 2009 Jul; 107(1):192-9.
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Saphenous vein harvest with the Mayo extraluminal dissector: is endothelial function preserved? J Thorac Cardiovasc Surg. 2009 Aug; 138(2):508-10.
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Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. J Neurosci. 2006 May 03; 26(18):4930-9.
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Up-regulation of microglial CD11b expression by nitric oxide. J Biol Chem. 2006 May 26; 281(21):14971-80.
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Chronic hypoxic decreases in soluble guanylate cyclase protein and enzyme activity are age dependent in fetal and adult ovine carotid arteries. J Appl Physiol (1985). 2006 Jun; 100(6):1857-66.
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Nitric oxide inhibits capacitative Ca2+ entry and enhances endoplasmic reticulum Ca2+ uptake in bovine vascular endothelial cells. J Physiol. 2002 Feb 15; 539(Pt 1):77-91.
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Reactive oxygen and nitrogen metabolites as mediators of secretory diarrhea. Gastroenterology. 1995 Dec; 109(6):2019-28.