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One or more keywords matched the following items that are connected to Bennett, David
Item TypeName
Concept Adaptor Proteins, Signal Transducing
Concept CLOCK Proteins
Concept Proto-Oncogene Proteins c-myc
Concept Proto-Oncogene Proteins c-fyn
Concept Polycomb-Group Proteins
Concept Vesicular Transport Proteins
Concept Membrane Proteins
Concept LDL-Receptor Related Proteins
Concept A Kinase Anchor Proteins
Concept Monomeric Clathrin Assembly Proteins
Concept DNA-Binding Proteins
Concept Vesicular Acetylcholine Transport Proteins
Concept 14-3-3 Proteins
Concept Membrane Transport Proteins
Concept Homeodomain Proteins
Concept Cytoskeletal Proteins
Concept Amyloidogenic Proteins
Concept Muscle Proteins
Concept Insulin Receptor Substrate Proteins
Concept Qa-SNARE Proteins
Concept Fatty Acid-Binding Proteins
Concept Carrier Proteins
Concept Cell Cycle Proteins
Concept Mitochondrial Proteins
Concept Vesicular Inhibitory Amino Acid Transport Proteins
Concept GTP-Binding Proteins
Concept Green Fluorescent Proteins
Concept Period Circadian Proteins
Concept SNARE Proteins
Concept Saccharomyces cerevisiae Proteins
Concept PrPC Proteins
Concept HSP27 Heat-Shock Proteins
Concept HSP70 Heat-Shock Proteins
Concept Nuclear Proteins
Concept Recombinant Proteins
Concept Neoplasm Proteins
Concept Caenorhabditis elegans Proteins
Concept Drosophila Proteins
Concept Microfilament Proteins
Concept Proto-Oncogene Proteins p21(ras)
Concept Acute-Phase Proteins
Concept Extracellular Matrix Proteins
Concept Intracellular Signaling Peptides and Proteins
Concept tau Proteins
Concept GPI-Linked Proteins
Concept Adaptor Proteins, Vesicular Transport
Concept R-SNARE Proteins
Concept Proto-Oncogene Proteins
Concept GTPase-Activating Proteins
Concept Nerve Tissue Proteins
Concept Tumor Suppressor Proteins
Concept RNA-Binding Proteins
Concept Intercellular Signaling Peptides and Proteins
Concept Repressor Proteins
Concept HSP90 Heat-Shock Proteins
Concept Proto-Oncogene Proteins c-akt
Concept Proteins
Concept Microtubule-Associated Proteins
Concept Munc18 Proteins
Concept Cholesterol Ester Transfer Proteins
Academic Article TDP-43 pathology, cognitive decline, and dementia in old age.
Academic Article Functional screening of Alzheimer pathology genome-wide association signals in Drosophila.
Academic Article Chronic corticosterone exposure alters postsynaptic protein levels of PSD-95, NR1, and synaptopodin in the mouse brain.
Academic Article Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Academic Article Cognitive reserve, presynaptic proteins and dementia in the elderly.
Academic Article Sex difference in daily rhythms of clock gene expression in the aged human cerebral cortex.
Academic Article Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
Academic Article Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease.
Academic Article Hippocampal sclerosis and TDP-43 pathology in aging and Alzheimer disease.
Academic Article The TMEM106B locus and TDP-43 pathology in older persons without FTLD.
Academic Article A common polymorphism near PER1 and the timing of human behavioral rhythms.
Academic Article Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease.
Academic Article The significance of Pin1 in the development of Alzheimer's disease.
Academic Article Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and alpha-synuclein pathology.
Academic Article Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
Academic Article Loss of Munc18-1 long splice variant in GABAergic terminals is associated with cognitive decline and increased risk of dementia in a community sample.
Academic Article Disentangling the effects of age and APOE on neuropathology and late life cognitive decline.
Academic Article Parahippocampal tau pathology in healthy aging, mild cognitive impairment, and early Alzheimer's disease.
Academic Article Soluble a-synuclein is a novel modulator of Alzheimer's disease pathophysiology.
Academic Article Relation of genomic variants for Alzheimer disease dementia to common neuropathologies.
Academic Article The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-e4 carriers.
Academic Article REST and stress resistance in ageing and Alzheimer's disease.
Academic Article Altered NEP2 expression and activity in mild cognitive impairment and Alzheimer's disease.
Academic Article Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.
Academic Article Alzheimer disease susceptibility loci: evidence for a protein network under natural selection.
Academic Article The complex PrP(c)-Fyn couples human oligomeric A? with pathological tau changes in Alzheimer's disease.
Academic Article Association of anxiety and depression with microtubule-associated protein 2- and synaptopodin-immunolabeled dendrite and spine densities in hippocampal CA3 of older humans.
Academic Article Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
Academic Article Tau conformational changes correspond to impairments of episodic memory in mild cognitive impairment and Alzheimer's disease.
Academic Article Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study.
Academic Article Body mass index is associated with biological CSF markers of core brain pathology of Alzheimer's disease.
Academic Article Accumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer disease.
Academic Article Alzheimer's disease: Unique markers for diagnosis & new treatment modalities.
Academic Article Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.
Academic Article Biochemical characterization of Abeta and tau pathologies in mild cognitive impairment and Alzheimer's disease.
Academic Article Temporal course of neurodegenerative effects on cognition in old age.
Academic Article Interaction of transactive response DNA binding protein 43 with nuclear factor ?B in mild cognitive impairment with episodic memory deficits.
Academic Article PAK inactivation impairs social recognition in 3xTg-AD Mice without increasing brain deposition of tau and A?.
Academic Article Mild cognitive impairment: is it Alzheimer's disease or not?
Academic Article Temporal course and pathologic basis of unawareness of memory loss in dementia.
Academic Article Cognitive performance correlates with cortical isopeptide immunoreactivity as well as Alzheimer type pathology.
Academic Article GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
Academic Article Education modifies the association of amyloid but not tangles with cognitive function.
Academic Article Decreases in soluble alpha-synuclein in frontal cortex correlate with cognitive decline in the elderly.
Academic Article Life-span cognitive activity, neuropathologic burden, and cognitive aging.
Academic Article Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease.
Academic Article The SORL1 gene and convergent neural risk for Alzheimer's disease across the human lifespan.
Academic Article A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers.
Academic Article Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
Academic Article NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.
Academic Article Lack of genetic association of cholesteryl ester transfer protein polymorphisms with late onset Alzheimers disease.
Academic Article Relation of neuropathology to cognition in persons without cognitive impairment.
Academic Article Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.
Academic Article The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults.
Academic Article Association of APOE with tau-tangle pathology with and without ?-amyloid.
Academic Article A genome-wide scan for common variants affecting the rate of age-related cognitive decline.
Academic Article Life extension factor klotho enhances cognition.
Academic Article Cerebrospinal fluid tau cleaved by caspase-6 reflects brain levels and cognition in aging and Alzheimer disease.
Academic Article Identification of Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation.
Academic Article Astroglial heme oxygenase-1 and the origin of corpora amylacea in aging and degenerating neural tissues.
Academic Article Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease.
Academic Article The CETP I405V polymorphism is associated with an increased risk of Alzheimer's disease.
Academic Article GSK3? Interactions with Amyloid Genes: An Autopsy Verification and Extension.
Academic Article The TMEM106B locus and TDP-43 pathology in older persons without FTLD.
Academic Article Activation of caspase-6 in aging and mild cognitive impairment.
Academic Article Author Response.
Academic Article Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense?oligonucleotides.
Academic Article Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.
Academic Article Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease.
Academic Article Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory.
Academic Article Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans.
Academic Article A novel Alzheimer disease locus located near the gene encoding tau protein.
Academic Article miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo.
Academic Article Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer's disease related cognitive functioning.
Academic Article TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia.
Academic Article Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.
Academic Article Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer's disease.
Academic Article Association of Cancer History with Alzheimer's Disease Dementia and Neuropathology.
Academic Article An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.
Academic Article Novel genetic loci associated with hippocampal volume.
Academic Article TOMM40'523 variant and cognitive decline in older persons with APOE e3/3 genotype.
Academic Article Association of Neuropathological Markers in the Parietal Cortex With Antemortem Cognitive Function in Persons With Mild Cognitive Impairment and Alzheimer Disease.
Academic Article Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
Academic Article Genetic epistasis regulates amyloid deposition in resilient aging.
Academic Article Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies.
Academic Article Selective lowering of synapsins induced by oligomeric a-synuclein exacerbates memory deficits.
Academic Article Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Academic Article Soluble Conformers of A? and Tau Alter Selective Proteins Governing Axonal Transport.
Academic Article Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment.
Academic Article Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer's disease.
Academic Article Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
Academic Article Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer's disease.
Academic Article APOE e4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans.
Academic Article Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
Academic Article Age and the association of dementia-related pathology with trajectories of cognitive decline.
Academic Article Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline.
Academic Article Genetic influence of plasma homocysteine on Alzheimer's disease.
Academic Article Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.
Academic Article Tissue Transglutaminase and Its Product Isopeptide Are Increased in Alzheimer's Disease and APPswe/PS1dE9 Double Transgenic Mice Brains.
Academic Article Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline.
Academic Article Frontotemporal dysregulation of the SNARE protein interactome is associated with faster cognitive decline in old age.
Academic Article Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of?Selective Neuronal Vulnerability.
Academic Article Reactive Oxygen Species-Mediated Loss of Synaptic Akt1 Signaling Leads to Deficient Activity-Dependent Protein Translation Early in Alzheimer's Disease.
Academic Article Neurodegenerative disease and cognitive retest learning.
Academic Article Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.
Academic Article Integrated biology approach reveals molecular and pathological interactions among Alzheimer's A?42, Tau, TREM2, and TYROBP in Drosophila models.
Academic Article Microscale fractionation facilitates detection of differentially expressed proteins in Alzheimer's disease brain samples.
Academic Article Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
Academic Article TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer's disease.
Academic Article Functional links between A? toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast.
Academic Article Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.
Academic Article A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease.
Academic Article Tau Activates Transposable Elements in Alzheimer's Disease.
Academic Article Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia.
Academic Article Sex-specific genetic predictors of Alzheimer's disease biomarkers.
Academic Article Reproductive period and epigenetic modifications of the oxidative phosphorylation pathway in the human prefrontal cortex.
Academic Article The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target.
Academic Article Sex differences in Alzheimer's disease and common neuropathologies of aging.
Academic Article Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in A? and TAU proteostasis.
Academic Article In vivo hippocampal subfield shape related to TDP-43, amyloid beta, and tau pathologies.
Academic Article Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.
Academic Article Physical activity, common brain pathologies, and cognition in community-dwelling older adults.
Academic Article Postmortem neurodegenerative markers and trajectories of decline in cognitive systems.
Academic Article Disentangling the genetics of lean mass.
Academic Article Associations of amygdala volume and shape with transactive response DNA-binding protein 43 (TDP-43) pathology in a community cohort of older adults.
Academic Article Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A?, tau, immunity and lipid processing.
Academic Article Brain IGFBP-5 modifies the relation of depressive symptoms to decline in cognition in older persons.
Academic Article Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer's Disease Patients.
Academic Article CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
Academic Article Association of TDP-43 Pathology With Domain-specific Literacy in Older Persons.
Academic Article cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis.
Academic Article Neuropsychological latent classes at enrollment and postmortem neuropathology.
Academic Article Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline.
Academic Article Sex differences in the genetic predictors of Alzheimer's pathology.
Academic Article Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease.
Academic Article Regulation of lifespan by neural excitation and REST.
Academic Article The synaptic pathology of cognitive life?.
Academic Article Quantitative Assessment of Pathological Tau Burden in Essential Tremor: A Postmortem Study.
Academic Article Shared Causal Paths underlying Alzheimer's dementia and Type 2 Diabetes.
Academic Article Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.
Academic Article Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain.
Academic Article Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease.
Academic Article Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology.
Academic Article Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons.
Academic Article BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathology.
Academic Article Integration of postmortem amygdala expression profiling, GWAS, and functional cell culture assays: neuroticism-associated synaptic vesicle glycoprotein 2A (SV2A) gene is regulated by miR-133a and miR-218.
Academic Article Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
Academic Article Recombinant tissue-type plasminogen activator versus a novel dosing regimen of urokinase in acute pulmonary embolism: a randomized controlled multicenter trial.
Academic Article Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics.
Academic Article Association of Low Systolic Blood Pressure with Postmortem Amyloid-? and Tau.
Academic Article A cortical immune network map identifies distinct microglial transcriptional programs associated with ?-amyloid and Tau pathologies.
Academic Article Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.
Academic Article A? (Amyloid Beta) and Tau Tangle Pathology Modifies the Association Between Small Vessel Disease and Cortical Microinfarcts.
Academic Article TOMM40-APOE haplotypes are associated with cognitive decline in non-demented Blacks.
Academic Article Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture.
Academic Article Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change and microvascular pathologies in community-dwelling older persons.
Academic Article Neuroticism alters the transcriptome of the frontal cortex to contribute to the cognitive decline and onset of Alzheimer's disease.
Academic Article Proteomic identification of select protein variants of the SNARE interactome associated with cognitive reserve in a large community sample.
Academic Article Systemic brain derived neurotrophic factor but not intestinal barrier integrity is associated with cognitive decline and incident Alzheimer's disease.
Academic Article Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia.
Academic Article Brain proteome-wide association study implicates novel proteins in depression pathogenesis.
Academic Article Tripartite Relationship Among Synaptic, Amyloid, and Tau Proteins: An In Vivo and Postmortem Study.
Academic Article Cortical proteins may provide motor resilience in older adults.
Academic Article Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics.
Academic Article A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3.
Academic Article Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease.
Academic Article Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors.
Academic Article Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE e2 protective effect in Alzheimer disease.
Academic Article BMI1 is associated with CS8F amyloid-? and rates of cognitive decline in Alzheimer's disease.
Academic Article Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice.
Academic Article Role of Retinoid X Receptors (RXRs) and dietary vitamin A in Alzheimer's disease: Evidence from clinicopathological and preclinical studies.
Academic Article Microglial Correlates of Late Life Physical Activity: Relationship with Synaptic and Cognitive Aging in Older Adults.
Academic Article Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue.
Academic Article Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance.
Academic Article Neuropathologic Correlates of Human Cortical Proteins in Alzheimer Disease and Related Dementias.
Academic Article Association of small vessel disease with tau pathology.
Academic Article Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ?2 for Alzheimer's disease.
Academic Article Cortical Proteins and Individual Differences in Cognitive Resilience in Older Adults.
Academic Article Progranulin mutations in clinical and neuropathological Alzheimer's disease.
Academic Article Identification of the A?37/42 peptide ratio in CSF as an improved A? biomarker for Alzheimer's disease.
Academic Article Association of Traumatic Brain Injury With and Without Loss of Consciousness With Neuropathologic Outcomes in Community-Dwelling Older Persons.
Academic Article Proteome-Wide Discovery of Cortical Proteins That May Provide Motor Resilience to Offset the Negative Effects of Pathologies in Older Adults.
Academic Article Pelargonidin and Berry Intake Association with Alzheimer's Disease Neuropathology: A Community-Based Study.
Academic Article Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is associated with lower R2 relaxation rate: an ex-vivo MRI and pathology investigation.
Academic Article Plasma p-tau181 and p-tau217 in discriminating PART, AD and other key neuropathologies in older adults.
Academic Article The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms.
Academic Article Alzheimer's Disease Pathology Outside of the Cerebrum Is Related to a Higher Odds of Dementia.
Academic Article Relation of Motor Impairments to Neuropathologic Changes of Limbic-Predominant Age-Related TDP-43 Encephalopathy in Older Adults.
Academic Article Estrogen Receptor Genes, Cognitive Decline, and Alzheimer Disease.
Academic Article Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities.
Academic Article Age-related and amyloid-beta-independent tau deposition and its downstream effects.
Academic Article The unique effect of TDP-43 on hippocampal subfield morphometry and cognition.
Academic Article Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease.
Academic Article Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities.
Concept CELF Proteins
Concept ADAMTS Proteins
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