GTPase-Activating Proteins
"GTPase-Activating Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that activate the GTPase of specific GTP-BINDING PROTEINS.
| Descriptor ID |
D020690
|
| MeSH Number(s) |
D12.644.360.325.150 D12.776.476.325.150
|
| Concept/Terms |
GTPase-Activating Proteins- GTPase-Activating Proteins
- GTPase Activating Proteins
- GAP Proteins
- GAP Protein
- GTPase-Activating Protein
- GTPase Activating Protein
|
Below are MeSH descriptors whose meaning is more general than "GTPase-Activating Proteins".
Below are MeSH descriptors whose meaning is more specific than "GTPase-Activating Proteins".
This graph shows the total number of publications written about "GTPase-Activating Proteins" by people in this website by year, and whether "GTPase-Activating Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 1 | 2 |
| 2015 | 3 | 0 | 3 |
| 2017 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "GTPase-Activating Proteins" by people in Profiles.
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CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT. Nat Commun. 2022 03 11; 13(1):1295.
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Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimers Dement. 2017 Jul; 13(7):727-738.
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Pseudomonas aeruginosa ExoT Induces Mitochondrial Apoptosis in Target Host Cells in a Manner That Depends on Its GTPase-activating Protein (GAP) Domain Activity. J Biol Chem. 2015 Nov 27; 290(48):29063-73.
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Pseudomonas aeruginosa ExoT Induces Atypical Anoikis Apoptosis in Target Host Cells by Transforming Crk Adaptor Protein into a Cytotoxin. PLoS Pathog. 2015 May; 11(5):e1004934.
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Pseudomonas aeruginosa exotoxin T induces potent cytotoxicity against a variety of murine and human cancer cell lines. J Med Microbiol. 2015 Feb; 64(Pt 2):164-73.
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The Pseudomonas aeruginosa type III secreted toxin ExoT is necessary and sufficient to induce apoptosis in epithelial cells. Cell Microbiol. 2008 Apr; 10(4):994-1007.
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Use of a novel coinfection system reveals a role for Rac1, H-Ras, and CrkII phosphorylation in Helicobacter pylori-induced host cell actin cytoskeletal rearrangements. FEMS Immunol Med Microbiol. 2007 Jul; 50(2):190-205.
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Pseudomonas aeruginosa type III-secreted toxin ExoT inhibits host-cell division by targeting cytokinesis at multiple steps. Proc Natl Acad Sci U S A. 2006 Oct 17; 103(42):15605-10.
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The ADP ribosyltransferase domain of Pseudomonas aeruginosa ExoT contributes to its biological activities. Infect Immun. 2004 Jan; 72(1):546-58.