| Item Type | Name |
|
Concept
|
Gene Expression Regulation, Enzymologic
|
|
Concept
|
Gene Expression Profiling
|
|
Concept
|
Regulatory Elements, Transcriptional
|
|
Concept
|
Genetic Pleiotropy
|
|
Concept
|
Gene Regulatory Networks
|
|
Concept
|
Multigene Family
|
|
Concept
|
Genes, Tumor Suppressor
|
|
Concept
|
Epistasis, Genetic
|
|
Concept
|
Gene Expression
|
|
Concept
|
Amino Acid Sequence
|
|
Concept
|
Trinucleotide Repeat Expansion
|
|
Concept
|
Gene Knock-In Techniques
|
|
Concept
|
Genome, Human
|
|
Concept
|
Gene Targeting
|
|
Concept
|
Transcriptome
|
|
Concept
|
Gene Rearrangement
|
|
Concept
|
Polymorphism, Single Nucleotide
|
|
Concept
|
Quantitative Trait Loci
|
|
Concept
|
Gene Library
|
|
Concept
|
Gene Expression Regulation, Neoplastic
|
|
Concept
|
Sequence Homology, Amino Acid
|
|
Concept
|
Gene-Environment Interaction
|
|
Concept
|
Exome
|
|
Concept
|
Genetic Loci
|
|
Concept
|
Genome
|
|
Concept
|
Pseudogenes
|
|
Concept
|
Gene Frequency
|
|
Concept
|
Gene Deletion
|
|
Concept
|
Alleles
|
|
Concept
|
Genes, Recessive
|
|
Concept
|
Gene Knockdown Techniques
|
|
Concept
|
Molecular Sequence Data
|
|
Concept
|
Gene Expression Regulation, Developmental
|
|
Concept
|
Gene Expression Regulation
|
|
Concept
|
Gene Dosage
|
|
Academic Article
|
GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP.
|
|
Academic Article
|
Novel late-onset Alzheimer disease loci variants associate with brain gene expression.
|
|
Academic Article
|
Sex difference in daily rhythms of clock gene expression in the aged human cerebral cortex.
|
|
Academic Article
|
Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease.
|
|
Academic Article
|
An inflection point in gene discovery efforts for neurodegenerative diseases: from syndromic diagnoses toward endophenotypes and the epigenome.
|
|
Academic Article
|
Genetic variation in the brain derived neurotrophic factor gene in Alzheimer's disease.
|
|
Academic Article
|
Variation in longevity gene KLOTHO is associated with greater cortical volumes.
|
|
Academic Article
|
The significance of Pin1 in the development of Alzheimer's disease.
|
|
Academic Article
|
24-hour rhythms of DNA methylation and their relation with rhythms of RNA expression in the human dorsolateral prefrontal cortex.
|
|
Academic Article
|
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
|
|
Academic Article
|
APOE e4 and the associations of seafood and long-chain omega-3 fatty acids with cognitive decline.
|
|
Academic Article
|
Genome-wide chromatin state transitions associated with developmental and environmental cues.
|
|
Academic Article
|
REST and stress resistance in ageing and Alzheimer's disease.
|
|
Academic Article
|
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
|
|
Academic Article
|
The complex PrP(c)-Fyn couples human oligomeric A? with pathological tau changes in Alzheimer's disease.
|
|
Academic Article
|
Neuropathologic intermediate phenotypes enhance association to Alzheimer susceptibility alleles.
|
|
Academic Article
|
Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
|
|
Academic Article
|
Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain.
|
|
Academic Article
|
Brain erythropoietin receptor expression in Alzheimer disease and mild cognitive impairment.
|
|
Academic Article
|
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.
|
|
Academic Article
|
Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant.
|
|
Academic Article
|
Genome-wide association study identifies 74 loci associated with educational attainment.
|
|
Academic Article
|
Higher brain BDNF gene expression is associated with slower cognitive decline in older adults.
|
|
Academic Article
|
A coding variant in CR1 interacts with APOE-e4 to influence cognitive decline.
|
|
Academic Article
|
Mitochondrial DNA rearrangements in aging human brain and in situ PCR of mtDNA.
|
|
Academic Article
|
APOE e4 increases risk for dementia in pure synucleinopathies.
|
|
Academic Article
|
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
|
|
Academic Article
|
The SORL1 gene and convergent neural risk for Alzheimer's disease across the human lifespan.
|
|
Academic Article
|
Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.
|
|
Academic Article
|
Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers.
|
|
Academic Article
|
Fragile X gene expansions are not associated with dementia.
|
|
Academic Article
|
Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment.
|
|
Academic Article
|
The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults.
|
|
Academic Article
|
GSK3? Interactions with Amyloid Genes: An Autopsy Verification and Extension.
|
|
Academic Article
|
Genetic variants in Alzheimer disease - molecular and brain network approaches.
|
|
Academic Article
|
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.
|
|
Academic Article
|
Is there a link between cancer and Alzheimer disease?
|
|
Academic Article
|
The epigenome in Alzheimer's disease: current state and approaches for a new path to gene discovery and understanding disease mechanism.
|
|
Academic Article
|
Apolipoprotein E epsilon4 and incidence of Alzheimer disease in a community population of older persons.
|
|
Academic Article
|
The apolipoprotein E epsilon 2 allele and decline in episodic memory.
|
|
Academic Article
|
Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.
|
|
Academic Article
|
Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory.
|
|
Academic Article
|
Alternative Approaches in Gene Discovery and Characterization in Alzheimer's Disease.
|
|
Academic Article
|
A novel Alzheimer disease locus located near the gene encoding tau protein.
|
|
Academic Article
|
GWAS for executive function and processing speed suggests involvement of the CADM2 gene.
|
|
Academic Article
|
miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo.
|
|
Academic Article
|
Gene expression elucidates functional impact of polygenic risk for schizophrenia.
|
|
Academic Article
|
Differential transcriptome expression in human nucleus accumbens as a function of loneliness.
|
|
Academic Article
|
Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1.
|
|
Academic Article
|
A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression.
|
|
Academic Article
|
A genome-wide profiling of brain DNA hydroxymethylation in Alzheimer's disease.
|
|
Academic Article
|
Polygenic risk scores in familial Alzheimer disease.
|
|
Academic Article
|
Selective lowering of synapsins induced by oligomeric a-synuclein exacerbates memory deficits.
|
|
Academic Article
|
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
|
|
Academic Article
|
Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer's disease.
|
|
Academic Article
|
Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
|
|
Academic Article
|
Neuronal-expressed microRNA-targeted pseudogenes compete with coding genes in the human brain.
|
|
Academic Article
|
Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline.
|
|
Academic Article
|
A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.
|
|
Academic Article
|
Loneliness 5 years ante-mortem is associated with disease-related differential gene expression in postmortem dorsolateral prefrontal cortex.
|
|
Academic Article
|
A transcriptomic atlas of aged human microglia.
|
|
Academic Article
|
A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans.
|
|
Academic Article
|
Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of?Selective Neuronal Vulnerability.
|
|
Academic Article
|
Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.
|
|
Academic Article
|
Integrated biology approach reveals molecular and pathological interactions among Alzheimer's A?42, Tau, TREM2, and TYROBP in Drosophila models.
|
|
Academic Article
|
Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
|
|
Academic Article
|
Genetic association of low density lipoprotein receptor and Alzheimer's disease.
|
|
Academic Article
|
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease.
|
|
Academic Article
|
Gene expression and DNA methylation are extensively coordinated with MRI-based brain microstructural characteristics.
|
|
Academic Article
|
The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target.
|
|
Academic Article
|
Multi-omic Directed Networks Describe Features of Gene Regulation in Aged Brains and Expand the Set of Genes Driving Cognitive Decline.
|
|
Academic Article
|
Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts.
|
|
Academic Article
|
Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
|
|
Academic Article
|
Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in A? and TAU proteostasis.
|
|
Academic Article
|
Hippocampal gene expression patterns linked to late-life physical activity oppose age and AD-related transcriptional decline.
|
|
Academic Article
|
Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria.
|
|
Academic Article
|
Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer's disease.
|
|
Academic Article
|
Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer's Disease.
|
|
Academic Article
|
TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits.
|
|
Academic Article
|
A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.
|
|
Academic Article
|
cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis.
|
|
Academic Article
|
APOE e4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease.
|
|
Academic Article
|
Rate of brain aging and APOE e4 are synergistic risk factors for Alzheimer's disease.
|
|
Academic Article
|
Bayesian integrative analysis of epigenomic and transcriptomic data identifies Alzheimer's disease candidate genes and networks.
|
|
Academic Article
|
Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.
|
|
Academic Article
|
Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology.
|
|
Academic Article
|
Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways.
|
|
Academic Article
|
Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.
|
|
Academic Article
|
Deconvolving the contributions of cell-type heterogeneity on cortical gene expression.
|
|
Academic Article
|
Integration of postmortem amygdala expression profiling, GWAS, and functional cell culture assays: neuroticism-associated synaptic vesicle glycoprotein 2A (SV2A) gene is regulated by miR-133a and miR-218.
|
|
Academic Article
|
Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics.
|
|
Academic Article
|
Genetic Factors of Alzheimer's Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study.
|
|
Academic Article
|
Single-cell transcriptomic analysis of Alzheimer's disease.
|
|
Academic Article
|
Genetic control of the human brain proteome.
|
|
Academic Article
|
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture.
|
|
Academic Article
|
Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia.
|
|
Academic Article
|
Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease.
|
|
Academic Article
|
Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study.
|
|
Academic Article
|
A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3.
|
|
Academic Article
|
Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE e2 protective effect in Alzheimer disease.
|
|
Academic Article
|
Cascading epigenomic analysis for identifying disease genes from the regulatory landscape of GWAS variants.
|
|
Academic Article
|
Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue.
|
|
Academic Article
|
Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance.
|
|
Academic Article
|
Blood and brain transcriptome analysis reveals APOE genotype-mediated and immune-related pathways involved in Alzheimer disease.
|
|
Academic Article
|
Genotype-phenotype correlation of T-cell subtypes reveals senescent and cytotoxic genes in Alzheimer's disease.
|