"Myelin Sheath" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The lipid-rich sheath surrounding AXONS in both the CENTRAL NERVOUS SYSTEMS and PERIPHERAL NERVOUS SYSTEM. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem.
| Descriptor ID |
D009186
|
| MeSH Number(s) |
A08.637.600.500 A08.637.800.500 A08.675.542.512.560 A08.800.800.690.500 A10.755.503 A11.284.149.165.600 A11.650.600.500 A11.650.800.500 A11.671.501.512.560 A11.671.514.553
|
| Concept/Terms |
Myelin Sheath- Myelin Sheath
- Myelin Sheaths
- Sheath, Myelin
- Sheaths, Myelin
|
Below are MeSH descriptors whose meaning is more general than "Myelin Sheath".
Below are MeSH descriptors whose meaning is more specific than "Myelin Sheath".
This graph shows the total number of publications written about "Myelin Sheath" by people in this website by year, and whether "Myelin Sheath" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 2 | 3 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myelin Sheath" by people in Profiles.
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Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosis. Glia. 2022 10; 70(10):1950-1970.
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Decreased myelin content of the fornix predicts poorer memory performance beyond vascular risk, hippocampal volume, and fractional anisotropy in nondemented older adults. Brain Imaging Behav. 2021 Oct; 15(5):2563-2571.
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Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology. Neuron. 2020 08 05; 107(3):496-508.e6.
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Pericyte degeneration causes white matter dysfunction in the mouse central nervous system. Nat Med. 2018 03; 24(3):326-337.
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Upregulation of Myelin Gene Expression by a Physically-Modified Saline via Phosphatidylinositol 3-Kinase-Mediated Activation of CREB: Implications for Multiple Sclerosis. Neurochem Res. 2018 Feb; 43(2):407-419.
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Cinnamon ameliorates experimental allergic encephalomyelitis in mice via regulatory T cells: implications for multiple sclerosis therapy. PLoS One. 2015; 10(1):e0116566.
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Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage. J Neurosci. 2013 Oct 30; 33(44):17232-46.
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In vivo quantification of white matter microstructure for use in aging: a focus on two emerging techniques. Am J Geriatr Psychiatry. 2014 Feb; 22(2):111-21.
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Up-regulation of ciliary neurotrophic factor in astrocytes by aspirin: implications for remyelination in multiple sclerosis. J Biol Chem. 2013 Jun 21; 288(25):18533-45.
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White matter hyperintensities in Parkinson's disease: do they explain the disparity between the postural instability gait difficulty and tremor dominant subtypes? PLoS One. 2013; 8(1):e55193.