"Keratinocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.
| Descriptor ID |
D015603
|
| MeSH Number(s) |
A11.436.397
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Keratinocytes".
Below are MeSH descriptors whose meaning is more specific than "Keratinocytes".
This graph shows the total number of publications written about "Keratinocytes" by people in this website by year, and whether "Keratinocytes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 2 | 1 | 3 |
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Below are the most recent publications written about "Keratinocytes" by people in Profiles.
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Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes. Proc Natl Acad Sci U S A. 2007 Sep 04; 104(36):14466-71.
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Expansion of vitiligo lesions is associated with reduced epidermal CDw60 expression and increased expression of HLA-DR in perilesional skin. Br J Dermatol. 2003 Oct; 149(4):739-48.
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Role for Id-1 in immunobiology of normal keratinocytes and in basal cell carcinoma. Exp Dermatol. 2003 Jun; 12(3):255-60.
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Innate immune-related receptors in normal and psoriatic skin. Arch Pathol Lab Med. 2003 Feb; 127(2):178-86.
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Pathways involved in proliferating, senescent and immortalized keratinocyte cell death mediated by two different TRAIL preparations. Exp Dermatol. 2002 Dec; 11(6):573-83.
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The enhanced IL-18 production by UVB irradiation requires ROI and AP-1 signaling in human keratinocyte cell line (HaCaT). Biochem Biophys Res Commun. 2002 Oct 25; 298(2):289-95.
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Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma. Cell Death Differ. 2002 Aug; 9(8):842-55.
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Avoiding premature apoptosis of normal epidermal cells. Nat Med. 2001 Apr; 7(4):385-6.
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Keratinocyte CDw60 expression is modulated by both a Th-1 type cytokine IFN-gamma and Th-2 cytokines IL-4 and IL-13: relevance to psoriasis. J Invest Dermatol. 2001 Feb; 116(2):305-12.
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Overexpression of CD1d by keratinocytes in psoriasis and CD1d-dependent IFN-gamma production by NK-T cells. J Immunol. 2000 Oct 01; 165(7):4076-85.