"Ascorbic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
| Descriptor ID |
D001205
|
| MeSH Number(s) |
D02.241.081.844.107 D02.241.511.902.107 D09.811.100
|
| Concept/Terms |
Ascorbic Acid- Ascorbic Acid
- Acid, Ascorbic
- L-Ascorbic Acid
- Acid, L-Ascorbic
- L Ascorbic Acid
- Vitamin C
Magnesium Ascorbate- Magnesium Ascorbate
- Ascorbate, Magnesium
- Magnesium di-L-Ascorbate
- Magnesium di L Ascorbate
- di-L-Ascorbate, Magnesium
- Magnesium Ascorbicum
|
Below are MeSH descriptors whose meaning is more general than "Ascorbic Acid".
Below are MeSH descriptors whose meaning is more specific than "Ascorbic Acid".
This graph shows the total number of publications written about "Ascorbic Acid" by people in this website by year, and whether "Ascorbic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 2 | 0 | 2 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ascorbic Acid" by people in Profiles.
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Vitamin C suppresses proliferation of the human melanoma cell SK-MEL-2 through the inhibition of cyclooxygenase-2 (COX-2) expression and the modulation of insulin-like growth factor II (IGF-II) production. J Cell Physiol. 2008 Jul; 216(1):180-8.
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The molecular mechanisms of vitamin C on cell cycle regulation in B16F10 murine melanoma. J Cell Biochem. 2007 Nov 01; 102(4):1002-10.
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Sodium ascorbate (vitamin C) induces apoptosis in melanoma cells via the down-regulation of transferrin receptor dependent iron uptake. J Cell Physiol. 2005 Jul; 204(1):192-7.
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Vitamin C downregulates interleukin-18 production by increasing reactive oxygen intermediate and mitogen-activated protein kinase signalling in B16F10 murine melanoma cells. Melanoma Res. 2003 Dec; 13(6):549-54.
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L-ascorbic acid (vitamin C) induces the apoptosis of B16 murine melanoma cells via a caspase-8-independent pathway. Cancer Immunol Immunother. 2003 Nov; 52(11):693-8.
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Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. JAMA. 2002 Jun 26; 287(24):3230-7.
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Analyses of vitamin C in biological samples with an emphasis on recent chromatographic techniques. Prog Clin Biol Res. 1988; 259:331-62.
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Modulation of an adenylate cyclase-linked serotonin (5-HT) receptor system in a neuroblastoma x brain explant hybrid cell line (NCB-20) by opiates, prostaglandins, and alpha 2-adrenergic agonists. Adv Biochem Psychopharmacol. 1983; 37:361-72.