"Podocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly differentiated epithelial cells of the visceral layer of BOWMAN CAPSULE of the KIDNEY. They are composed of a cell body with major CELL SURFACE EXTENSIONS and secondary fingerlike extensions called pedicels. They enwrap the KIDNEY GLOMERULUS capillaries with their cell surface extensions forming a filtration structure. The pedicels of neighboring podocytes interdigitate with each other leaving between them filtration slits that are bridged by an extracellular structure impermeable to large macromolecules called the slit diaphragm, and provide the last barrier to protein loss in the KIDNEY.
| Descriptor ID |
D050199
|
| MeSH Number(s) |
A05.810.453.324.359.372.650 A05.810.453.736.520.720 A11.436.720
|
| Concept/Terms |
Podocytes- Podocytes
- Podocyte
- Glomerular Visceral Epithelial Cells
- Visceral Epithelial Cells, Glomerular
- Epithelial Cells, Glomerular Visceral
|
Below are MeSH descriptors whose meaning is more general than "Podocytes".
Below are MeSH descriptors whose meaning is more specific than "Podocytes".
This graph shows the total number of publications written about "Podocytes" by people in this website by year, and whether "Podocytes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Podocytes" by people in Profiles.
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SuPAR mediates viral response proteinuria by rapidly changing podocyte function. Nat Commun. 2023 07 21; 14(1):4414.
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The zinc fingers and homeoboxes 2 protein ZHX2 and its interacting proteins regulate upstream pathways in podocyte diseases. Kidney Int. 2020 04; 97(4):753-764.
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Nonimmune cell-derived ICOS ligand functions as a renoprotective av?3 integrin-selective antagonist. J Clin Invest. 2019 04 01; 129(4):1713-1726.
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TRPC5 Does Not Cause or Aggravate Glomerular Disease. J Am Soc Nephrol. 2018 02; 29(2):409-415.
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A tripartite complex of suPAR, APOL1 risk variants and av?3 integrin on podocytes mediates chronic kidney disease. Nat Med. 2017 Aug; 23(8):945-953.
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Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1. J Biol Chem. 2017 Jan 13; 292(2):732-747.
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Dynamin Autonomously Regulates Podocyte Focal Adhesion Maturation. J Am Soc Nephrol. 2017 02; 28(2):446-451.
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HIV-associated nephropathy: experimental models. Contrib Nephrol. 2011; 169:270-285.
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Transcriptional regulation of podocyte disease. Transl Res. 2007 May; 149(5):237-42.
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ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome. J Biol Chem. 2006 Dec 22; 281(51):39681-92.