Platelet Glycoprotein GPIIb-IIIa Complex
"Platelet Glycoprotein GPIIb-IIIa Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.
| Descriptor ID |
D019039
|
| MeSH Number(s) |
D12.776.395.550.625.785 D12.776.543.550.625.785 D12.776.543.750.705.408.460.700 D12.776.543.750.705.675.784
|
| Concept/Terms |
Platelet Glycoprotein GPIIb-IIIa Complex- Platelet Glycoprotein GPIIb-IIIa Complex
- Platelet Glycoprotein GPIIb IIIa Complex
- Glycoproteins IIb-IIIa
- Glycoproteins IIb IIIa
- Integrin alpha-IIb beta-3
- Integrin alpha IIb beta 3
- beta-3, Integrin alpha-IIb
- Integrin alphaIIbbeta3
- alphaIIbbeta3, Integrin
- GPIIb-IIIa Receptors
- GPIIb IIIa Receptors
- Receptors, GPIIb-IIIa
|
Below are MeSH descriptors whose meaning is more general than "Platelet Glycoprotein GPIIb-IIIa Complex".
Below are MeSH descriptors whose meaning is more specific than "Platelet Glycoprotein GPIIb-IIIa Complex".
This graph shows the total number of publications written about "Platelet Glycoprotein GPIIb-IIIa Complex" by people in this website by year, and whether "Platelet Glycoprotein GPIIb-IIIa Complex" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Platelet Glycoprotein GPIIb-IIIa Complex" by people in Profiles.
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Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice. Blood. 2013 Aug 08; 122(6):1052-61.
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Intra-arterial reteplase and intravenous abciximab in patients with acute ischemic stroke: an open-label, dose-ranging, phase I study. Neurosurgery. 2006 Oct; 59(4):789-96; discussion 796-7.
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Pharmacoinvasive management of acute coronary syndrome in the setting of percutaneous coronary intervention: evidence-based, site- and spectrum-of-care strategies for optimizing patient outcomes in NSTE-ACS. J Invasive Cardiol. 2003 Sep; 15(9):536-53.
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Improved in-hospital outcomes in acute coronary syndromes (unstable angina/non-ST segment elevation myocardial infarction) despite similar TIMI risk scores. J Invasive Cardiol. 2003 Sep; 15(9):502-6.
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The dark side of platelet glycoprotein IIb/IIIa receptor inhibitors during percutaneous coronary interventions. Am J Cardiol. 2003 May 15; 91(10):1199-202.
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Frequency of abrupt vessel closure and side branch occlusion after percutaneous coronary intervention in a 6.5-year period (1994 to 2000) at a single medical center. Am J Cardiol. 2002 May 15; 89(10):1151-5.
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Clinical outcomes of patients treated with the cutting balloon and Sr-90 beta-irradiation for instent restenosis. Cardiovasc Radiat Med. 2002 Jan-Mar; 3(1):12-5.
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Unstable angina and non-Q wave myocardial infarction: does the clinical diagnosis have therapeutic implications? J Am Coll Cardiol. 1999 Jan; 33(1):107-18.
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Differential regulation of integrin-mediated proplatelet formation and megakaryocyte spreading. J Cell Physiol. 1995 Jun; 163(3):597-607.