"Megakaryocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Very large BONE MARROW CELLS which release mature BLOOD PLATELETS.
| Descriptor ID |
D008533
|
| MeSH Number(s) |
A11.148.479 A15.378.316.479
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Megakaryocytes".
Below are MeSH descriptors whose meaning is more specific than "Megakaryocytes".
This graph shows the total number of publications written about "Megakaryocytes" by people in this website by year, and whether "Megakaryocytes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1997 | 2 | 0 | 2 |
| 2004 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Megakaryocytes" by people in Profiles.
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Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation. Hum Genet. 2022 Jan; 141(1):127-146.
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Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice. Cell Res. 2011 Mar; 21(3):530-45.
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Successful treatment of amegakaryocytic thrombocytopenia with eltrombopag in a patient with systemic lupus erythematosus (SLE). Clin Adv Hematol Oncol. 2010 Nov; 8(11):806-9.
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Isolation of primary megakaryocytes and studies of proplatelet formation. Methods Mol Biol. 2004; 272:281-91.
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Recombinant human interleukin-11 directly promotes megakaryocytopoiesis in vitro. Blood. 1997 Nov 15; 90(10):3893-902.
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Effect of recombinant interleukin-6 and thrombopoietin on isolated guinea pig bone marrow megakaryocyte protein phosphorylation and proplatelet formation. Blood Cells Mol Dis. 1997 Aug; 23(2):252-68.
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Differential regulation of integrin-mediated proplatelet formation and megakaryocyte spreading. J Cell Physiol. 1995 Jun; 163(3):597-607.
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Megakaryocyte proplatelet-like process formation in vitro is inhibited by serum prothrombin, a process which is blocked by matrix-bound glycosaminoglycans. Exp Hematol. 1993 Feb; 21(2):372-81.
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Extracellular matrix stimulation of guinea pig megakaryocyte proplatelet formation in vitro is mediated through the vitronectin receptor. Exp Hematol. 1992 Dec; 20(11):1316-22.
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Lipid and membrane fluidity abnormalities in platelets and megakaryocytes of the hereditary macrothrombocytopenic Wistar Furth rat. Biochim Biophys Acta. 1991 Nov 18; 1070(1):253-8.