Sodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications for Alzheimer disease therapy.

Sodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications for Alzheimer disease therapy. J Biol Chem. 2013 Mar 22; 288(12):8299-8312.

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subject areas

Administration, Oral
Alzheimer Disease
Animals
Astrocytes
Brain-Derived Neurotrophic Factor
Cell Shape
Cells, Cultured
Cyclic AMP Response Element-Binding Protein
Formates
Glial Fibrillary Acidic Protein
Hippocampus
Humans
Male
Memory
Mice
Mice, Inbred C57BL
Mice, Transgenic
Neurons
Neurotrophin 3
Phenylbutyrates
Phosphorylation
Primary Cell Culture
Protein Kinase C
Protein Processing, Post-Translational
Receptors, Nerve Growth Factor
Up-Regulation

authors with profiles

Kalipada Pahan