"Amitriptyline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
| Descriptor ID |
D000639
|
| MeSH Number(s) |
D02.455.426.559.847.181.384.100 D04.615.181.384.100
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Amitriptyline".
Below are MeSH descriptors whose meaning is more specific than "Amitriptyline".
This graph shows the total number of publications written about "Amitriptyline" by people in this website by year, and whether "Amitriptyline" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amitriptyline" by people in Profiles.
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Comparison of naproxen with cyclobenzaprine, oxycodone-acetaminophen, and placebo for the treatment of acute low back pain. CJEM. 2016 Nov; 18(6):491-494.
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Tricyclic antidepressant amitriptyline alters sarcoplasmic reticulum calcium handling in ventricular myocytes. Am J Physiol Heart Circ Physiol. 2008 Nov; 295(5):H2008-16.
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Susceptibility to spontaneous MAOI hypertensive episodes. J Clin Psychiatry. 1991 Dec; 52(12):513-4.