 Mitogen-Activated Protein Kinase 9
"Mitogen-Activated Protein Kinase 9" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with molecular sizes of 48 and 54 KD exist due to multiple ALTERNATIVE SPLICING.
| Descriptor ID |
D048056
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567.513.750 D08.811.913.696.620.682.700.646.750.374.750 D12.644.360.450.340.750 D12.776.476.450.340.750
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| Concept/Terms |
Mitogen-Activated Protein Kinase 9- Mitogen-Activated Protein Kinase 9
- Mitogen Activated Protein Kinase 9
- c-jun N-terminal Kinase 2
- c jun N terminal Kinase 2
- JNK2 Kinase
- MAPK9 Mitogen-Activated Protein Kinase
- MAPK9 Mitogen Activated Protein Kinase
- Stress-Activated Protein Kinase JNK2
- Stress Activated Protein Kinase JNK2
- c-jun Kinase-2
- Kinase-2, c-jun
- c jun Kinase 2
- JNK2 Stress-Activated Protein Kinase
- JNK2 Stress Activated Protein Kinase
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Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 9".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 9".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 9" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 9" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 | | 2018 | 3 | 0 | 3 | | 2020 | 2 | 0 | 2 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase 9" by people in Profiles.
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McKee C, Bare DJ, Ai X. Stress-driven cardiac calcium mishandling via a kinase-to-kinase crosstalk. Pflugers Arch. 2021 03; 473(3):363-375.
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Yan J, Bare DJ, DeSantiago J, Zhao W, Mei Y, Chen Z, Ginsburg K, Solaro RJ, Wolska BM, Bers DM, Chen SRW, Ai X. JNK2, a Newly-Identified SERCA2 Enhancer, Augments an Arrhythmic [Ca2+]SR Leak-Load Relationship. Circ Res. 2021 02 19; 128(4):455-470.
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Yang M, Barrios J, Yan J, Zhao W, Yuan S, Dong E, Ai X. Causal roles of stress kinase JNK2 in DNA methylation and binge alcohol withdrawal-evoked behavioral deficits. Pharmacol Res. 2021 02; 164:105375.
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Yan J, Thomson JK, Zhao W, Gao X, Huang F, Chen B, Liang Q, Song LS, Fill M, Ai X. Role of Stress Kinase JNK in Binge Alcohol-Evoked Atrial Arrhythmia. J Am Coll Cardiol. 2018 04 03; 71(13):1459-1470.
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Gao X, Wu X, Yan J, Zhang J, Zhao W, DeMarco D, Zhang Y, Bakhos M, Mignery G, Sun J, Li Z, Fill M, Ai X. Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIId expression in the aged atrium. Cardiovasc Res. 2018 04 01; 114(5):737-746.
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Yan J, Zhao W, Thomson JK, Gao X, DeMarco DM, Carrillo E, Chen B, Wu X, Ginsburg KS, Bakhos M, Bers DM, Anderson ME, Song LS, Fill M, Ai X. Stress Signaling JNK2 Crosstalk With CaMKII Underlies Enhanced Atrial Arrhythmogenesis. Circ Res. 2018 03 16; 122(6):821-835.
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Wood SJ, Goldufsky JW, Bello D, Masood S, Shafikhani SH. Pseudomonas aeruginosa ExoT Induces Mitochondrial Apoptosis in Target Host Cells in a Manner That Depends on Its GTPase-activating Protein (GAP) Domain Activity. J Biol Chem. 2015 Nov 27; 290(48):29063-73.
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