Cyclins
"Cyclins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEPENDENT KINASES. They generally function as ENZYME ACTIVATORS that drive the CELL CYCLE through transitions between phases. A subset of cyclins may also function as transcriptional regulators.
Descriptor ID |
D016213
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MeSH Number(s) |
D12.644.360.262 D12.776.167.218 D12.776.476.262
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cyclins".
Below are MeSH descriptors whose meaning is more specific than "Cyclins".
This graph shows the total number of publications written about "Cyclins" by people in this website by year, and whether "Cyclins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 2 | 2 | 1997 | 1 | 0 | 1 | 2000 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclins" by people in Profiles.
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Albrengues J, Wysocki RW, Maiorino L, Egeblad M. Re-cyclin' Cell-Cycle Components to Make NETs. Dev Cell. 2017 11 20; 43(4):379-380.
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Wang M, Chen M, Zheng G, Dillard B, Tallarico M, Ortiz Z, Holterman AX. Transcriptional activation by growth hormone of HNF-6-regulated hepatic genes, a potential mechanism for improved liver repair during biliary injury in mice. Am J Physiol Gastrointest Liver Physiol. 2008 Aug; 295(2):G357-66.
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Kuropkat C, Venkatesan TK, Caldarelli DD, Panje WR, Hutchinson J, Preisler HD, Coon JS, Werner JA. Abnormalities of molecular regulators of proliferation and apoptosis in carcinoma of the oral cavity and oropharynx. Auris Nasus Larynx. 2002 Apr; 29(2):165-74.
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Ollmann M, Young LM, Di Como CJ, Karim F, Belvin M, Robertson S, Whittaker K, Demsky M, Fisher WW, Buchman A, Duyk G, Friedman L, Prives C, Kopczynski C. Drosophila p53 is a structural and functional homolog of the tumor suppressor p53. Cell. 2000 Mar 31; 101(1):91-101.
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Maki CG, Howley PM. Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation. Mol Cell Biol. 1997 Jan; 17(1):355-63.
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Lee J, Romeo A, Kosman DJ. Transcriptional remodeling and G1 arrest in dioxygen stress in Saccharomyces cerevisiae. J Biol Chem. 1996 Oct 04; 271(40):24885-93.
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Maki CG, Huibregtse JM, Howley PM. In vivo ubiquitination and proteasome-mediated degradation of p53(1). Cancer Res. 1996 Jun 01; 56(11):2649-54.
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