 Ion Channel Gating
"Ion Channel Gating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability.
| Descriptor ID |
D015640
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| MeSH Number(s) |
G02.111.087.800.400 G02.149.115.800.400 G04.299.500 G04.299.880.400 G07.265.337.500 G07.700.240.500
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| Concept/Terms |
Ion Channel Gating- Ion Channel Gating
- Gating, Ion Channel
- Gatings, Ion Channel
- Ion Channel Gatings
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Below are MeSH descriptors whose meaning is more general than "Ion Channel Gating".
Below are MeSH descriptors whose meaning is more specific than "Ion Channel Gating".
This graph shows the total number of publications written about "Ion Channel Gating" by people in this website by year, and whether "Ion Channel Gating" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1988 | 0 | 1 | 1 | | 1989 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 | | 1991 | 3 | 4 | 7 | | 1992 | 1 | 1 | 2 | | 1993 | 0 | 4 | 4 | | 1994 | 2 | 3 | 5 | | 1995 | 2 | 3 | 5 | | 1996 | 1 | 5 | 6 | | 1997 | 1 | 4 | 5 | | 1998 | 4 | 4 | 8 | | 1999 | 3 | 2 | 5 | | 2000 | 0 | 3 | 3 | | 2001 | 3 | 1 | 4 | | 2002 | 2 | 1 | 3 | | 2003 | 4 | 3 | 7 | | 2004 | 5 | 1 | 6 | | 2005 | 3 | 0 | 3 | | 2006 | 3 | 4 | 7 | | 2007 | 4 | 0 | 4 | | 2008 | 8 | 4 | 12 | | 2009 | 4 | 0 | 4 | | 2010 | 3 | 2 | 5 | | 2011 | 3 | 1 | 4 | | 2012 | 2 | 0 | 2 | | 2013 | 3 | 5 | 8 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 2 | 3 | | 2016 | 1 | 1 | 2 | | 2017 | 2 | 3 | 5 | | 2018 | 4 | 0 | 4 | | 2019 | 2 | 0 | 2 | | 2020 | 0 | 2 | 2 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ion Channel Gating" by people in Profiles.
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Sokolov VS, Cherny VV, Ayuyan AG, DeCoursey TE. Analysis of an electrostatic mechanism for ?pH dependent gating of the voltage-gated proton channel, HV1, supports a contribution of protons to gating charge. Biochim Biophys Acta Bioenerg. 2021 11 01; 1862(11):148480.
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Cherny VV, Musset B, Morgan D, Thomas S, Smith SME, DeCoursey TE. Engineered high-affinity zinc binding site reveals gating configurations of a human proton channel. J Gen Physiol. 2020 10 05; 152(10).
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Yao J, Sun B, Institoris A, Zhan X, Guo W, Song Z, Liu Y, Hiess F, Boyce AKJ, Ni M, Wang R, Ter Keurs H, Back TG, Fill M, Thompson RJ, Turner RW, Gordon GR, Chen SRW. Limiting RyR2 Open Time Prevents Alzheimer's Disease-Related Neuronal Hyperactivity and Memory Loss but Not ß-Amyloid Accumulation. Cell Rep. 2020 09 22; 32(12):108169.
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Gillespie D. Recruiting RyRs to Open in a Ca2+ Release Unit: Single-RyR Gating Properties Make RyR Group Dynamics. Biophys J. 2020 01 07; 118(1):232-242.
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Banh R, Cherny VV, Morgan D, Musset B, Thomas S, Kulleperuma K, Smith SME, Pomès R, DeCoursey TE. Hydrophobic gasket mutation produces gating pore currents in closed human voltage-gated proton channels. Proc Natl Acad Sci U S A. 2019 09 17; 116(38):18951-18961.
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Fill M, Gillespie D. Ryanodine Receptor Open Times Are Determined in the Closed State. Biophys J. 2018 10 02; 115(7):1160-1165.
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DeCoursey TE. Gating currents indicate complex gating of voltage-gated proton channels. Proc Natl Acad Sci U S A. 2018 09 11; 115(37):9057-9059.
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Cherny VV, Morgan D, Thomas S, Smith SME, DeCoursey TE. Histidine168 is crucial for ?pH-dependent gating of the human voltage-gated proton channel, hHV1. J Gen Physiol. 2018 06 04; 150(6):851-862.
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Thomas S, Cherny VV, Morgan D, Artinian LR, Rehder V, Smith SME, DeCoursey TE. Exotic properties of a voltage-gated proton channel from the snail Helisoma trivolvis. J Gen Physiol. 2018 06 04; 150(6):835-850.
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Ferreira Gregorio J, Pequera G, Manno C, Ríos E, Brum G. The voltage sensor of excitation-contraction coupling in mammals: Inactivation and interaction with Ca2. J Gen Physiol. 2017 Nov 06; 149(11):1041-1058.
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