14-3-3 Proteins
"14-3-3 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of signal-transducing adaptor proteins present in wide variety of eukaryotes. They are PHOSPHOSERINE and PHOSPHOTHREONINE binding proteins involved in important cellular processes including SIGNAL TRANSDUCTION; CELL CYCLE control; APOPTOSIS; and cellular stress responses. 14-3-3 proteins function by interacting with other signal-transducing proteins and effecting changes in their enzymatic activity and subcellular localization. The name 14-3-3 derives from numerical designations used in the original fractionation patterns of the proteins.
Descriptor ID |
D048948
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MeSH Number(s) |
D12.644.360.024.050 D12.776.157.057.002 D12.776.476.024.050
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Concept/Terms |
14-3-3 Proteins- 14-3-3 Proteins
- 14 3 3 Proteins
- Brain 14-3-3 Protein
- 14-3-3 Protein, Brain
- Brain 14 3 3 Protein
- Protein 14-3-3
- 14-3-3 Protein
- 14 3 3 Protein
14-3-3 Protein, tau Isoform- 14-3-3 Protein, tau Isoform
- 14 3 3 Protein, tau Isoform
- 14-3-3tau Protein
- 14 3 3tau Protein
- Protein, 14-3-3tau
- 14-3-3 tau Protein
- 14 3 3 tau Protein
14-3-3 Protein, zeta Isoform- 14-3-3 Protein, zeta Isoform
- 14 3 3 Protein, zeta Isoform
- 14-3-3 zeta Protein
- 14 3 3 zeta Protein
- 14-3-3zeta Protein
- 14 3 3zeta Protein
14-3-3 Protein, eta Isoform- 14-3-3 Protein, eta Isoform
- 14 3 3 Protein, eta Isoform
- 14-3-3eta Protein
- 14 3 3eta Protein
- 14-3-3 eta Protein
- 14 3 3 eta Protein
- eta Protein, 14-3-3
14-3-3 Protein, epsilon Isoform- 14-3-3 Protein, epsilon Isoform
- 14 3 3 Protein, epsilon Isoform
- 14-3-3epsilon Protein
- 14 3 3epsilon Protein
- 14-3-3 epsilon Protein
- 14 3 3 epsilon Protein
14-3-3 Protein, gamma Isoform- 14-3-3 Protein, gamma Isoform
- 14 3 3 Protein, gamma Isoform
- 14-3-3gamma Protein
- 14 3 3gamma Protein
- 14-3-3 gamma Protein
- 14 3 3 gamma Protein
14-3-3 Protein, beta Isoform- 14-3-3 Protein, beta Isoform
- 14 3 3 Protein, beta Isoform
- 14-3-3beta Protein
- 14 3 3beta Protein
- 14-3-3 beta Protein
- 14 3 3 beta Protein
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Below are MeSH descriptors whose meaning is more general than "14-3-3 Proteins".
Below are MeSH descriptors whose meaning is more specific than "14-3-3 Proteins".
This graph shows the total number of publications written about "14-3-3 Proteins" by people in this website by year, and whether "14-3-3 Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 | 2011 | 2 | 0 | 2 | 2014 | 0 | 1 | 1 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "14-3-3 Proteins" by people in Profiles.
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Ojelade SA, Lee TV, Giagtzoglou N, Yu L, Ugur B, Li Y, Duraine L, Zuo Z, Petyuk V, De Jager PL, Bennett DA, Arenkiel BR, Bellen HJ, Shulman JM. cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis. Cell Rep. 2019 08 13; 28(7):1799-1813.e5.
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Brobeil A, Viard M, Petri MK, Steger K, Tag C, Wimmer M. Memory and PTPIP51--a new protein in hippocampus and cerebellum. Mol Cell Neurosci. 2015 Jan; 64:61-73.
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Petri MK, Koch P, Stenzinger A, Kuchelmeister K, Nestler U, Paradowska A, Steger K, Brobeil A, Viard M, Wimmer M. PTPIP51, a positive modulator of the MAPK/Erk pathway, is upregulated in glioblastoma and interacts with 14-3-3ß and PTP1B in situ. Histol Histopathol. 2011 12; 26(12):1531-43.
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Liao KA, Tsay YG, Huang LC, Huang HY, Li CF, Wu TF. Search for the tumor-associated proteins of oral squamous cell carcinoma collected in Taiwan using proteomics strategy. J Proteome Res. 2011 May 06; 10(5):2347-58.
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Faul C, Donnelly M, Merscher-Gomez S, Chang YH, Franz S, Delfgaauw J, Chang JM, Choi HY, Campbell KN, Kim K, Reiser J, Mundel P. The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. Nat Med. 2008 Sep; 14(9):931-8.
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