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Meghan Moran

TitleAssistant Professor
InstitutionRush University, Rush Medical College
DepartmentAnatomy and Cell Biology
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    Collapse Overview 
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    My Scopus ID is 40762104000.

    Research Areas:
    I am a bone biologist interested in the molecular interactions between the gut, gut microbiome and bone as a mechanistic pathway to delaying or mitigating arthroplasty failure due to peri-implant particle-induced osteolysis. Osteolysis is inflammatory bone loss, in this case, stimulated by wear particles from the implant. The gut may provide a point of intervention in the inflammatory response to an orthopedic implant and the gut microbiome may act as a biomarker for implant health. My research may lead to a reduced need for invasive revision surgery, which is currently the treatment for failed implants. Previously, I focused on bone regeneration genetics to identify poor bone repair post-injury.

    My Faculty Profile at Rush University Medical Center:
    https://www.rushu.rush.edu/faculty/meghan-moran-phd

    My Laboratory:
    https://www.rushu.rush.edu/research/departmental-research/cell-molecular-medicine-research/laboratory-meghan-moran-phd

    My NCBI Bibliography:
    https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/40498281/?sort=date&direction=descending

    My Scopus:
    https://www.scopus.com/authid/detail.uri?authorId=56604656200
    https://www.scopus.com/authid/detail.uri?authorId=40762104000

    Education:
    PhD, Kent State University/Northeast Ohio Medical University

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wilson BM, Ko FC, Moran MM, Adra A, Rasmussen MB, Thymann T, Sangild PT, Sumner DR. Skeletal consequences of preterm birth in pigs as a model for preterm infants. J Bone Miner Res. 2024 Jul 23; 39(6):791-803. PMID: 38655758.
      Citations:    
    2. Plaas AHK, Moran MM, Sandy JD, Hascall VC. Aggrecan and Hyaluronan: The Infamous Cartilage Polyelectrolytes - Then and Now. Adv Exp Med Biol. 2023; 1402:3-29. PMID: 37052843.
      Citations:    
    3. Moran MM, Ko FC, Mesner LD, Calabrese GM, Al-Barghouthi BM, Farber CR, Sumner DR, Moran MM, Ko FC, Mesner LD, Calabrese GM, Al-Barghouthi BM, Farber CR, Sumner DR. Intramembranous bone regeneration in diversity outbred mice is heritable. Bone. 2022 11; 164:116524. PMID: 36028119; PMCID: PMC9798271.
      Citations:    
    4. Ko FC, Moran MM, Ross RD, Sumner DR, Ko FC, Moran MM, Ross RD, Sumner DR. Activation of canonical Wnt signaling accelerates intramembranous bone regeneration in male mice. J Orthop Res. 2022 08; 40(8):1834-1843. PMID: 34811780; PMCID: PMC9124233.
      Citations:    
    5. Moran MM, Wessman P, Rolfson O, Bohl DD, K?rrholm J, Keshavarzian A, Sumner DR, Moran MM, Wessman P, Rolfson O, Bohl DD, K?rrholm J, Keshavarzian A, Sumner DR. The risk of revision following total hip arthroplasty in patients with inflammatory bowel disease, a registry based study. PLoS One. 2021; 16(11):e0257310. PMID: 34735461; PMCID: PMC8568118.
      Citations:    
    6. Moran MM, Wilson BM, Li J, Engen PA, Naqib A, Green SJ, Virdi AS, Plaas A, Forsyth CB, Keshavarzian A, Sumner DR, Moran MM, Wilson BM, Li J, Engen PA, Naqib A, Green SJ, Virdi AS, Plaas A, Forsyth CB, Keshavarzian A, Sumner DR. The gut microbiota may be a novel pathogenic mechanism in loosening of orthopedic implants in rats. FASEB J. 2020 11; 34(11):14302-14317. PMID: 32931052; PMCID: PMC8025663.
      Citations:    
    7. Wilson BM, Moran MM, Meagher MJ, Ross RD, Mashiatulla M, Virdi AS, Sumner DR. Early changes in serum osteocalcin and body weight are predictive of implant fixation in a rat model of implant loosening. J Orthop Res. 2020 06; 38(6):1216-1227. PMID: 31825107.
      Citations:    
    8. Moran MM, Wilson BM, Ross RD, Virdi AS, Sumner DR. Arthrotomy-based preclinical models of particle-induced osteolysis: A systematic review. J Orthop Res. 2017 12; 35(12):2595-2605. PMID: 28548682.
      Citations:    
    9. Mashiatulla M, Moran MM, Chan D, Li J, Freedman JD, Snyder BD, Grinstaff MW, Plaas A, Sumner DR. Murine articular cartilage morphology and compositional quantification with high resolution cationic contrast-enhanced ?CT. J Orthop Res. 2017 12; 35(12):2740-2748. PMID: 28471533.
      Citations:    
    10. Moran MM, Sena K, McNulty MA, Sumner DR, Virdi AS. Intramembranous bone regeneration and implant placement using mechanical femoral marrow ablation: rodent models. Bonekey Rep. 2016; 5:837. PMID: 27648259.
      Citations:    
    11. Moran MM, Virdi AS, Sena K, Mazzone SR, McNulty MA, Sumner DR. Intramembranous bone regeneration differs among common inbred mouse strains following marrow ablation. J Orthop Res. 2015 Sep; 33(9):1374-81. PMID: 25808034.
      Citations:    
    12. Moran MM, Nummela S, Thewissen JG. Development of the skull of the pantropical spotted dolphin (Stenella attenuata). Anat Rec (Hoboken). 2011 Oct; 294(10):1743-56. PMID: 21901843.
      Citations:    
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