Meghan Moran
Title | Assistant Professor |
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Institution | Rush University, Rush Medical College |
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Department | Anatomy and Cell Biology |
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Overview My Scopus ID is 40762104000.
Research Areas: I am a bone biologist interested in the molecular interactions between the gut, gut microbiome and bone as a mechanistic pathway to delaying or mitigating arthroplasty failure due to peri-implant particle-induced osteolysis. Osteolysis is inflammatory bone loss, in this case, stimulated by wear particles from the implant. The gut may provide a point of intervention in the inflammatory response to an orthopedic implant and the gut microbiome may act as a biomarker for implant health. My research may lead to a reduced need for invasive revision surgery, which is currently the treatment for failed implants. Previously, I focused on bone regeneration genetics to identify poor bone repair post-injury.
My Faculty Profile at Rush University Medical Center: https://www.rushu.rush.edu/faculty/meghan-moran-phd
My Laboratory: https://www.rushu.rush.edu/research/departmental-research/cell-molecular-medicine-research/laboratory-meghan-moran-phd
My NCBI Bibliography: https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/40498281/?sort=date&direction=descending
My Scopus: https://www.scopus.com/authid/detail.uri?authorId=56604656200 https://www.scopus.com/authid/detail.uri?authorId=40762104000
Education: PhD, Kent State University/Northeast Ohio Medical University
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Ko FC, Moran MM, Ross RD, Sumner DR. Activation of canonical Wnt signaling accelerates intramembranous bone regeneration in male mice. J Orthop Res. 2021 Nov 22. PMID: 34811780.
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Moran MM, Wessman P, Rolfson O, Bohl DD, Kärrholm J, Keshavarzian A, Sumner DR. The risk of revision following total hip arthroplasty in patients with inflammatory bowel disease, a registry based study. PLoS One. 2021; 16(11):e0257310. PMID: 34735461.
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Moran MM, Wilson BM, Li J, Engen PA, Naqib A, Green SJ, Virdi AS, Plaas A, Forsyth CB, Keshavarzian A, Sumner DR. The gut microbiota may be a novel pathogenic mechanism in loosening of orthopedic implants in rats. FASEB J. 2020 11; 34(11):14302-14317. PMID: 32931052.
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Wilson BM, Moran MM, Meagher MJ, Ross RD, Mashiatulla M, Virdi AS, Sumner DR. Early changes in serum osteocalcin and body weight are predictive of implant fixation in a rat model of implant loosening. J Orthop Res. 2020 06; 38(6):1216-1227. PMID: 31825107.
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Moran MM, Wilson BM, Ross RD, Virdi AS, Sumner DR. Arthrotomy-based preclinical models of particle-induced osteolysis: A systematic review. J Orthop Res. 2017 12; 35(12):2595-2605. PMID: 28548682.
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Mashiatulla M, Moran MM, Chan D, Li J, Freedman JD, Snyder BD, Grinstaff MW, Plaas A, Sumner DR. Murine articular cartilage morphology and compositional quantification with high resolution cationic contrast-enhanced µCT. J Orthop Res. 2017 12; 35(12):2740-2748. PMID: 28471533.
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Moran MM, Sena K, McNulty MA, Sumner DR, Virdi AS. Intramembranous bone regeneration and implant placement using mechanical femoral marrow ablation: rodent models. Bonekey Rep. 2016; 5:837. PMID: 27648259.
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Moran MM, Virdi AS, Sena K, Mazzone SR, McNulty MA, Sumner DR. Intramembranous bone regeneration differs among common inbred mouse strains following marrow ablation. J Orthop Res. 2015 Sep; 33(9):1374-81. PMID: 25808034.
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Moran MM, Nummela S, Thewissen JG. Development of the skull of the pantropical spotted dolphin (Stenella attenuata). Anat Rec (Hoboken). 2011 Oct; 294(10):1743-56. PMID: 21901843.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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Year | Publications |
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2011 | 1 | 2015 | 1 | 2016 | 1 | 2017 | 2 | 2019 | 1 | 2020 | 1 | 2021 | 2 |
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