"DNA Methylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.
| Descriptor ID |
D019175
|
| MeSH Number(s) |
G02.111.035.538.161 G02.111.218 G03.059.538.161 G05.206
|
| Concept/Terms |
DNA Methylation- DNA Methylation
- DNA Methylations
- Methylation, DNA
- Methylations, DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA Methylation".
Below are MeSH descriptors whose meaning is more specific than "DNA Methylation".
This graph shows the total number of publications written about "DNA Methylation" by people in this website by year, and whether "DNA Methylation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 4 | 1 | 5 |
| 2017 | 4 | 2 | 6 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA Methylation" by people in Profiles.
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Epigenetic inactivation of the autophagy-lysosomal system in appendix in Parkinson's disease. Nat Commun. 2021 08 26; 12(1):5134.
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A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids. Nat Commun. 2021 06 28; 12(1):3987.
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Maintenance DNA methylation is essential for regulatory T cell development and stability of suppressive function. J Clin Invest. 2020 12 01; 130(12):6571-6587.
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Epigenomic analysis of Parkinson's disease neurons identifies Tet2 loss as neuroprotective. Nat Neurosci. 2020 10; 23(10):1203-1214.
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Amelioration of Autoimmune Arthritis in Mice Treated With the DNA Methyltransferase Inhibitor 5'-Azacytidine. Arthritis Rheumatol. 2019 08; 71(8):1265-1275.
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DNA methylation variability in Alzheimer's disease. Neurobiol Aging. 2019 04; 76:35-44.
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An Epigenome-Wide Association Study of Obesity-Related Traits. Am J Epidemiol. 2018 08 01; 187(8):1662-1669.
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Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline. JAMA Neurol. 2017 12 01; 74(12):1473-1480.
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Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results. Neuropsychopharmacology. 2018 02; 43(3):503-512.
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Epigenome-Wide Association Study Identifies Methylation Sites Associated With Liver Enzymes and Hepatic Steatosis. Gastroenterology. 2017 10; 153(4):1096-1106.e2.