 Dopamine
"Dopamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
| Descriptor ID |
D004298
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| MeSH Number(s) |
D02.092.211.215.311.342 D02.092.311.342
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| Concept/Terms |
Dopamine- Dopamine
- 4-(2-Aminoethyl)-1,2-benzenediol
- Hydroxytyramine
- 3,4-Dihydroxyphenethylamine
- 3,4 Dihydroxyphenethylamine
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Below are MeSH descriptors whose meaning is more general than "Dopamine".
Below are MeSH descriptors whose meaning is more specific than "Dopamine".
This graph shows the total number of publications written about "Dopamine" by people in this website by year, and whether "Dopamine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1982 | 1 | 1 | 2 | | 1983 | 0 | 1 | 1 | | 1984 | 1 | 1 | 2 | | 1985 | 1 | 0 | 1 | | 1987 | 1 | 1 | 2 | | 1988 | 0 | 1 | 1 | | 1989 | 1 | 0 | 1 | | 1990 | 3 | 1 | 4 | | 1991 | 2 | 0 | 2 | | 1992 | 0 | 1 | 1 | | 1993 | 3 | 1 | 4 | | 1994 | 2 | 2 | 4 | | 1995 | 1 | 0 | 1 | | 1996 | 3 | 0 | 3 | | 1997 | 1 | 0 | 1 | | 1998 | 4 | 1 | 5 | | 1999 | 1 | 2 | 3 | | 2000 | 5 | 0 | 5 | | 2001 | 1 | 2 | 3 | | 2002 | 5 | 4 | 9 | | 2003 | 1 | 2 | 3 | | 2004 | 4 | 2 | 6 | | 2005 | 1 | 3 | 4 | | 2006 | 5 | 3 | 8 | | 2007 | 5 | 4 | 9 | | 2008 | 5 | 2 | 7 | | 2009 | 4 | 2 | 6 | | 2010 | 2 | 2 | 4 | | 2011 | 4 | 4 | 8 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 0 | 2 | 2 | | 2017 | 0 | 1 | 1 | | 2018 | 3 | 0 | 3 | | 2020 | 1 | 2 | 3 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dopamine" by people in Profiles.
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Houser MC, Caudle WM, Chang J, Kannarkat GT, Yang Y, Kelly SD, Oliver D, Joers V, Shannon KM, Keshavarzian A, Tansey MG. Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology. Acta Neuropathol Commun. 2021 08 19; 9(1):139.
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Dagan M, Herman T, Bernad-Elazari H, Gazit E, Maidan I, Giladi N, Mirelman A, Manor B, Hausdorff JM. Dopaminergic therapy and prefrontal activation during walking in individuals with Parkinson's disease: does the levodopa overdose hypothesis extend to gait? J Neurol. 2021 Feb; 268(2):658-668.
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Jankovic J, Okun MS, Kordower JH. Stem Cells: Scientific and Ethical Quandaries of a Personalized Approach to Parkinson's Disease. Mov Disord. 2020 08; 35(8):1312-1314.
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Napier TC, Kirby A, Persons AL. The role of dopamine pharmacotherapy and addiction-like behaviors in Parkinson's disease. Prog Neuropsychopharmacol Biol Psychiatry. 2020 08 30; 102:109942.
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Napier TC, Persons AL. Pharmacological insights into impulsive-compulsive spectrum disorders associated with dopaminergic therapy. Eur J Neurosci. 2019 08; 50(3):2492-2502.
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Rangasamy SB, Dasarathi S, Pahan P, Jana M, Pahan K. Low-Dose Aspirin Upregulates Tyrosine Hydroxylase and Increases Dopamine Production in Dopaminergic Neurons: Implications for Parkinson's Disease. J Neuroimmune Pharmacol. 2019 06; 14(2):173-187.
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Pal G, Ouyang B, Verhagen L, Serrano G, Shill HA, Adler CH, Beach TG, Kordower JH. Probing the striatal dopamine system for a putative neuroprotective effect of deep brain stimulation in Parkinson's disease. Mov Disord. 2018 04; 33(4):652-654.
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Wakeman DR, Hiller BM, Marmion DJ, McMahon CW, Corbett GT, Mangan KP, Ma J, Little LE, Xie Z, Perez-Rosello T, Guzman JN, Surmeier DJ, Kordower JH. Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In?Vivo. Stem Cell Reports. 2017 07 11; 9(1):149-161.
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Ghosh A, Tyson T, George S, Hildebrandt EN, Steiner JA, Madaj Z, Schulz E, Machiela E, McDonald WG, Escobar Galvis ML, Kordower JH, Van Raamsdonk JM, Colca JR, Brundin P. Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease. Sci Transl Med. 2016 12 07; 8(368):368ra174.
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Kordower JH, Vinuela A, Chu Y, Isacson O, Redmond DE. Parkinsonian monkeys with prior levodopa-induced dyskinesias followed by fetal dopamine precursor grafts do not display graft-induced dyskinesias. J Comp Neurol. 2017 02 15; 525(3):498-512.
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