 AMP-Activated Protein Kinases
"AMP-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Intracellular signaling protein kinases that play a signaling role in the regulation of cellular energy metabolism. Their activity largely depends upon the concentration of cellular AMP which is increased under conditions of low energy or metabolic stress. AMP-activated protein kinases modify enzymes involved in LIPID METABOLISM, which in turn provide substrates needed to convert AMP into ATP.
| Descriptor ID |
D055372
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| MeSH Number(s) |
D08.811.913.696.620.682.700.085 D12.644.360.062 D12.776.476.062
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| Concept/Terms |
AMP-Activated Protein Kinases- AMP-Activated Protein Kinases
- AMP Activated Protein Kinases
- PRKAA
- AMP-Activated Protein Kinase
- AMP Activated Protein Kinase
- AMPK
- 5'-AMP-Activated Protein Kinase
- 5' AMP Activated Protein Kinase
- AMP-Activated Kinase
- AMP Activated Kinase
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Below are MeSH descriptors whose meaning is more general than "AMP-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "AMP-Activated Protein Kinases".
This graph shows the total number of publications written about "AMP-Activated Protein Kinases" by people in this website by year, and whether "AMP-Activated Protein Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 | | 2016 | 2 | 1 | 3 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "AMP-Activated Protein Kinases" by people in Profiles.
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Li J, Zhang B, Liu WX, Lu K, Pan H, Wang T, Oh CD, Yi D, Huang J, Zhao L, Ning G, Xing C, Xiao G, Liu-Bryan R, Feng S, Chen D. Metformin limits osteoarthritis development and progression through activation of AMPK signalling. Ann Rheum Dis. 2020 05; 79(5):635-645.
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Das V, Kroin JS, Moric M, McCarthy RJ, Buvanendran A. Response to 'Antihyperalgesia effect of AMP-activated protein kinase (AMPK) activators in a mouse model of postoperative pain'. Reg Anesth Pain Med. 2020 03; 45(3):250-251.
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Herter-Sprie GS, Koyama S, Korideck H, Hai J, Deng J, Li YY, Buczkowski KA, Grant AK, Ullas S, Rhee K, Cavanaugh JD, Neupane NP, Christensen CL, Herter JM, Makrigiorgos GM, Hodi FS, Freeman GJ, Dranoff G, Hammerman PS, Kimmelman AC, Wong KK. Synergy of radiotherapy and PD-1 blockade in Kras-mutant lung cancer. JCI Insight. 2016 06 16; 1(9):e87415.
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Tandon M, Chen Z, Othman AH, Pratap J. Role of Runx2 in IGF-1Rß/Akt- and AMPK/Erk-dependent growth, survival and sensitivity towards metformin in breast cancer bone metastasis. Oncogene. 2016 09 08; 35(36):4730-40.
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Price TJ, Das V, Dussor G. Adenosine Monophosphate-activated Protein Kinase (AMPK) Activators For the Prevention, Treatment and Potential Reversal of Pathological Pain. Curr Drug Targets. 2016; 17(8):908-20.
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Hong EG, Kim BW, Jung DY, Kim JH, Yu T, Seixas Da Silva W, Friedline RH, Bianco SD, Seslar SP, Wakimoto H, Berul CI, Russell KS, Lee KW, Larsen PR, Bianco AC, Kim JK. Cardiac expression of human type 2 iodothyronine deiodinase increases glucose metabolism and protects against doxorubicin-induced cardiac dysfunction in male mice. Endocrinology. 2013 Oct; 154(10):3937-46.
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