 Thrombin
"Thrombin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme formed from PROTHROMBIN that converts FIBRINOGEN to FIBRIN.
| Descriptor ID |
D013917
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| MeSH Number(s) |
D08.811.277.656.300.760.855 D08.811.277.656.959.350.855 D12.776.124.125.890 D23.119.960
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| Concept/Terms |
Thrombostat- Thrombostat
- Park Davis Brand of Thrombin
- Pfizer Brand of Thrombin
- Thrombin Pfizer Brand
Thrombinar- Thrombinar
- Jones Brand of Thrombin
- Thrombin Jones Brand
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Below are MeSH descriptors whose meaning is more general than "Thrombin".
Below are MeSH descriptors whose meaning is more specific than "Thrombin".
This graph shows the total number of publications written about "Thrombin" by people in this website by year, and whether "Thrombin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1982 | 0 | 1 | 1 | | 1983 | 1 | 0 | 1 | | 1993 | 1 | 1 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2011 | 1 | 1 | 2 | | 2012 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Thrombin" by people in Profiles.
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Irwin RM, Bonassar LJ, Cohen I, Matuska AM, Commins J, Cole B, Fortier LA. The clot thickens: Autologous and allogeneic fibrin sealants are mechanically equivalent in an ex vivo model of cartilage repair. PLoS One. 2019; 14(11):e0224756.
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Farrell MR, Abdelsayed GA, Ziegelmann MJ, Levine LA. A Comparison of Hemostatic Patches Versus Pericardium Allograft for the Treatment of Complex Peyronie's Disease With Penile Prosthesis and Plaque Incision. Urology. 2019 07; 129:113-118.
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Mikecz K. Editorial: Ratiometric Optical Imaging of Subclinical Inflammation With a Thrombin-Cleavable Probe: A Future Tool for the In Vivo Visualization of Clinically Silent Synovitis? Arthritis Rheumatol. 2018 01; 70(1):4-6.
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Cowan C, Muraleedharan CK, O'Donnell JJ, Singh PK, Lum H, Kumar A, Xu S. MicroRNA-146 inhibits thrombin-induced NF-?B activation and subsequent inflammatory responses in human retinal endothelial cells. Invest Ophthalmol Vis Sci. 2014 Jul 01; 55(8):4944-51.
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Pandrea I, Cornell E, Wilson C, Ribeiro RM, Ma D, Kristoff J, Xu C, Haret-Richter GS, Trichel A, Apetrei C, Landay A, Tracy R. Coagulation biomarkers predict disease progression in SIV-infected nonhuman primates. Blood. 2012 Aug 16; 120(7):1357-66.
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Madhusudhan T, Wang H, Straub BK, Gröne E, Zhou Q, Shahzad K, Müller-Krebs S, Schwenger V, Gerlitz B, Grinnell BW, Griffin JH, Reiser J, Gröne HJ, Esmon CT, Nawroth PP, Isermann B. Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes. Blood. 2012 Jan 19; 119(3):874-83.
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Simpson ML, Goldenberg NA, Jacobson LJ, Bombardier CG, Hathaway WE, Manco-Johnson MJ. Simultaneous thrombin and plasmin generation capacities in normal and abnormal states of coagulation and fibrinolysis in children and adults. Thromb Res. 2011 Apr; 127(4):317-23.
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Qiao J, Holian O, Lee BS, Huang F, Zhang J, Lum H. Phosphorylation of GTP dissociation inhibitor by PKA negatively regulates RhoA. Am J Physiol Cell Physiol. 2008 Nov; 295(5):C1161-8.
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Ke Y, Lum H, Solaro RJ. Inhibition of endothelial barrier dysfunction by P21-activated kinase-1. Can J Physiol Pharmacol. 2007 Mar-Apr; 85(3-4):281-8.
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Miyamoto K, Masuda K, Inoue N, Okuma M, Muehleman C, An HS. Anti-adhesion properties of a thrombin-based hemostatic gelatin in a canine laminectomy model: a biomechanical, biochemical, and histologic study. Spine (Phila Pa 1976). 2006 Feb 15; 31(4):E91-7.
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