"Prothrombin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.
Descriptor ID |
D011516
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MeSH Number(s) |
D08.622.709 D12.776.124.125.800 D23.119.945
|
Concept/Terms |
Prothrombin- Prothrombin
- Factor II
- Blood Coagulation Factor II
- Differentiation Reversal Factor
- Factor, Differentiation Reversal
- Coagulation Factor II
- Factor II, Coagulation
- II, Coagulation Factor
|
Below are MeSH descriptors whose meaning is more general than "Prothrombin".
Below are MeSH descriptors whose meaning is more specific than "Prothrombin".
This graph shows the total number of publications written about "Prothrombin" by people in this website by year, and whether "Prothrombin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 1 | 0 | 1 |
2005 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Prothrombin" by people in Profiles.
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Bypassing agent prophylaxis in people with hemophilia A or B with inhibitors. Cochrane Database Syst Rev. 2017 09 25; 9:CD011441.
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Procoagulant stimulus processing by the intrinsic pathway of blood plasma coagulation. Biomaterials. 2005 Jun; 26(16):2965-73.
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Prevalence of anti-cardiolipin, anti-beta2 glycoprotein I, and anti-prothrombin antibodies in young patients with epilepsy. Epilepsia. 2002 Jan; 43(1):52-9.
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Megakaryocyte proplatelet-like process formation in vitro is inhibited by serum prothrombin, a process which is blocked by matrix-bound glycosaminoglycans. Exp Hematol. 1993 Feb; 21(2):372-81.