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Josefina Ramos-Franco

TitleAssociate Professor
InstitutionRush University, Rush Medical College
DepartmentPhysiology and Biophysics
Address1750 West Harrison St
Chicago IL 60612
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    Collapse Overview 
    Collapse overview
    My Scopus ID is 6505921249.
    My NIH COMMONS name is JRAMOS-FRANCO.

    Research Areas:
    Calcium release mediated by IP3R and RyR channels, mechanisms of local calcium control in cells.

    My Faculty Profile at Rush University Medical Center:
    https://www.rushu.rush.edu/faculty/josefina-ramos-franco-md-phd

    My Laboratory:
    https://www.rushu.rush.edu/research/departmental-research/physiology-and-biophysics-research/laboratory-josefina-ramos-franco-md-phd

    My NCBI Bibliography:
    https://www.ncbi.nlm.nih.gov/pubmed/?term=Ramos-Franco+J

    My Scopus:
    https://www.scopus.com/authid/detail.uri?authorId=6505921249

    Education:
    MD, Universidad Autonoma de Puebla, Mexico
    PhD, Universidad Nacional Autonoma de Mexico


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Tambeaux A, Aguilar-S?nchez Y, Santiago DJ, Mascitti M, DiNovo KM, Mej?a-Alvarez R, Fill M, Wayne Chen SR, Ramos-Franco J. Ligand sensitivity of type-1 inositol 1,4,5-trisphosphate receptor is enhanced by the D2594K mutation. Pflugers Arch. 2023 05; 475(5):569-581. PMID: 36881190.
      View in: PubMed
    2. Sun B, Ni M, Tian S, Guo W, Cai S, Sondergaard MT, Chen Y, Mu Y, Estillore JP, Wang R, Chen J, Overgaard MT, Fill M, Ramos-Franco J, Nyegaard M, Wayne Chen SR. A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice. J Cell Physiol. 2022 08; 237(8):3305-3316. PMID: 35621185.
      View in: PubMed
    3. Blancard M, Touat-Hamici Z, Aguilar-Sanchez Y, Yin L, Vaksmann G, Roux-Buisson N, Fressart V, Denjoy I, Klug D, Neyroud N, Ramos-Franco J, Gomez AM, Guicheney P. A Type 2 Ryanodine Receptor Variant in the Helical Domain 2 Associated with an Impairment of the Adrenergic Response. J Pers Med. 2021 Jun 20; 11(6). PMID: 34202968.
      View in: PubMed
    4. Yin L, Zahradnikova A, Rizzetto R, Boncompagni S, Rabesahala de Meritens C, Zhang Y, Joanne P, Marqu?s-Sul? E, Aguilar-S?nchez Y, Fern?ndez-Tenorio M, Villejoubert O, Li L, Wang YY, Mateo P, Nicolas V, Gerbaud P, Lai FA, Perrier R, ?lvarez JL, Niggli E, Valdivia HH, Valdivia CR, Ramos-Franco J, Zorio E, Zissimopoulos S, Protasi F, Benitah JP, G?mez AM. Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation. Circ Res. 2021 07 23; 129(3):e35-e52. PMID: 34111951.
      View in: PubMed
    5. Aguilar-Sanchez Y, Rodriguez de Yurre A, Argenziano M, Escobar AL, Ramos-Franco J. Transmural Autonomic Regulation of Cardiac Contractility at the Intact Heart Level. Front Physiol. 2019; 10:773. PMID: 31333477.
      View in: PubMed
    6. Musial TF, Molina-Campos E, Bean LA, Ybarra N, Borenstein R, Russo ML, Buss EW, Justus D, Neuman KM, Ayala GD, Mullen SA, Voskobiynyk Y, Tulisiak CT, Fels JA, Corbett NJ, Carballo G, Kennedy CD, Popovic J, Ramos-Franco J, Fill M, Pergande MR, Borgia JA, Corbett GT, Pahan K, Han Y, Chetkovich DM, Vassar RJ, Byrne RW, Matthew Oh M, Stoub TR, Remy S, Disterhoft JF, Nicholson DA. Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease. Neurobiol Learn Mem. 2018 10; 154:141-157. PMID: 29906573.
      View in: PubMed
    7. Ramos-Franco J, Fill M. Approaching ryanodine receptor therapeutics from the calcin angle. J Gen Physiol. 2016 05; 147(5):369-73. PMID: 27114611.
      View in: PubMed
    8. Ramos-Franco J, Aguilar-Sanchez Y, Escobar AL. Intact Heart Loose Patch Photolysis Reveals Ionic Current Kinetics During Ventricular Action Potentials. Circ Res. 2016 Jan 22; 118(2):203-15. PMID: 26565013.
      View in: PubMed
    9. Escobar AL, Perez CG, Reyes ME, Lucero SG, Kornyeyev D, Mej?a-Alvarez R, Ramos-Franco J. Role of inositol 1,4,5-trisphosphate in the regulation of ventricular Ca(2+) signaling in intact mouse heart. J Mol Cell Cardiol. 2012 Dec; 53(6):768-79. PMID: 22960455.
      View in: PubMed
    10. Porta M, Zima AV, Nani A, Diaz-Sylvester PL, Copello JA, Ramos-Franco J, Blatter LA, Fill M. Single ryanodine receptor channel basis of caffeine's action on Ca2+ sparks. Biophys J. 2011 Feb 16; 100(4):931-8. PMID: 21320437.
      View in: PubMed
    11. Ramos-Franco J, Gomez AM, Nani A, Liu Y, Copello JA, Fill M. Ryanodol action on calcium sparks in ventricular myocytes. Pflugers Arch. 2010 Sep; 460(4):767-76. PMID: 20419313.
      View in: PubMed
    12. Qin J, Valle G, Nani A, Chen H, Ramos-Franco J, Nori A, Volpe P, Fill M. Ryanodine receptor luminal Ca2+ regulation: swapping calsequestrin and channel isoforms. Biophys J. 2009 Oct 07; 97(7):1961-70. PMID: 19804727.
      View in: PubMed
    13. Porta M, Diaz-Sylvester PL, Nani A, Ramos-Franco J, Copello JA. Ryanoids and imperatoxin affect the modulation of cardiac ryanodine receptors by dihydropyridine receptor Peptide A. Biochim Biophys Acta. 2008 Nov; 1778(11):2469-79. PMID: 18722342.
      View in: PubMed
    14. Snopko RM, Ramos-Franco J, Di Maio A, Karko KL, Manley C, Piedras-Renter?a E, Mej?a-Alvarez R. Ca2+ sparks and cellular distribution of ryanodine receptors in developing cardiomyocytes from rat. J Mol Cell Cardiol. 2008 Jun; 44(6):1032-1044. PMID: 18468619.
      View in: PubMed
    15. Snopko RM, Aromolaran AS, Karko KL, Ramos-Franco J, Blatter LA, Mej?a-Alvarez R. Cell culture modifies Ca2+ signaling during excitation-contraction coupling in neonate cardiac myocytes. Cell Calcium. 2007 Jan; 41(1):13-25. PMID: 16908061.
      View in: PubMed
    16. P?rez CG, Copello JA, Li Y, Karko KL, G?mez L, Ramos-Franco J, Fill M, Escobar AL, Mej?a-Alvarez R. Ryanodine receptor function in newborn rat heart. Am J Physiol Heart Circ Physiol. 2005 May; 288(5):H2527-40. PMID: 15626694.
      View in: PubMed
    17. Ramos J, Jung W, Ramos-Franco J, Mignery GA, Fill M. Single channel function of inositol 1,4,5-trisphosphate receptor type-1 and -2 isoform domain-swap chimeras. J Gen Physiol. 2003 May; 121(5):399-411. PMID: 12695486.
      View in: PubMed
    18. Ramos-Franco J, Bare D, Caenepeel S, Nani A, Fill M, Mignery G. Single-channel function of recombinant type 2 inositol 1,4, 5-trisphosphate receptor. Biophys J. 2000 Sep; 79(3):1388-99. PMID: 10969001.
      View in: PubMed
    19. Ramos-Franco J, Galvan D, Mignery GA, Fill M. Location of the permeation pathway in the recombinant type 1 inositol 1,4,5-trisphosphate receptor. J Gen Physiol. 1999 Aug; 114(2):243-50. PMID: 10436000.
      View in: PubMed
    20. Ramos-Franco J, Caenepeel S, Fill M, Mignery G. Single channel function of recombinant type-1 inositol 1,4,5-trisphosphate receptor ligand binding domain splice variants. Biophys J. 1998 Dec; 75(6):2783-93. PMID: 9826600.
      View in: PubMed
    21. Ramos-Franco J, Fill M, Mignery GA. Isoform-specific function of single inositol 1,4,5-trisphosphate receptor channels. Biophys J. 1998 Aug; 75(2):834-9. PMID: 9675184.
      View in: PubMed
    22. Perez PJ, Ramos-Franco J, Fill M, Mignery GA. Identification and functional reconstitution of the type 2 inositol 1,4,5-trisphosphate receptor from ventricular cardiac myocytes. J Biol Chem. 1997 Sep 19; 272(38):23961-9. PMID: 9295347.
      View in: PubMed
    23. Ramos-Franco J, Lo CF, Breitwieser GE. Platelet-activating factor receptor-dependent activation of the muscarinic K+ current in bullfrog atrial myocytes. Circ Res. 1993 Apr; 72(4):786-94. PMID: 8383014.
      View in: PubMed
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