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Anna Spagnoli

TitleProfessor
InstitutionRush University, Rush Medical College
DepartmentPediatrics
Address1735 W. Harrison St.
Chicago IL 60612
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    Collapse Overview 
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    My Scopus ID is 7005262450.
    My NIH COMMONS name is SPAGNOA.


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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Esposito A, Kl?ppel M, Wilson BM, Meka SRK, Spagnoli A. CXCR4 mediates the effects of IGF-1R signaling in rodent bone homeostasis and fracture repair. Bone. 2023 01; 166:116600. PMID: 36368465.
      View in: PubMed
    2. Khalid SI, Thomson KB, Becerra AZ, Omotosho P, Spagnoli A, Torquati A. Rates, Risks, and Time to Fracture in Patients Undergoing Laparoscopic Vertical Sleeve Gastrectomy versus Roux-en-Y Gastric Bypass. Ann Surg Open. 2021 Dec; 2(4):e099. PMID: 37637884.
      View in: PubMed
    3. Rossi I, Omotosho P, Poirier J, Spagnoli A, Torquati A. Roux-en-Y gastric bypass decreases serum inflammatory markers and cardiovascular risk factors in obese diabetics. Surgery. 2021 03; 169(3):539-542. PMID: 33168209.
      View in: PubMed
    4. Esposito A, Wang L, Li T, Miranda M, Spagnoli A. Role of Prx1-expressing skeletal cells and Prx1-expression in fracture repair. Bone. 2020 10; 139:115521. PMID: 32629173.
      View in: PubMed
    5. Khalid SI, Omotosho PA, Spagnoli A, Torquati A. Association of Bariatric Surgery With Risk of Fracture in Patients With Severe Obesity. JAMA Netw Open. 2020 06 01; 3(6):e207419. PMID: 32520360.
      View in: PubMed
    6. Tangalakis LL, Tabone L, Spagnoli A, Muehlbauer M, Omotosho P, Torquati A. Effects of Roux-en-Y Gastric Bypass on Osteoclast Activity and Bone Density in Morbidly Obese Patients with Type 2 Diabetes. Obes Surg. 2020 01; 30(1):290-295. PMID: 31471767.
      View in: PubMed
    7. Torquati A, Shantavasinkul PC, Omotosho P, Corsino L, Spagnoli A. Perioperative changes in prouroguanylin hormone response in severely obese subjects after bariatric surgery. Surgery. 2019 10; 166(4):456-459. PMID: 31472974.
      View in: PubMed
    8. Ramakrishna H, Li T, He T, Temple J, King MW, Spagnoli A. Tissue engineering a tendon-bone junction with biodegradable braided scaffolds. Biomater Res. 2019; 23:11. PMID: 31131112.
      View in: PubMed
    9. Li T, Chubinskaya S, Esposito A, Jin X, Tagliafierro L, Loeser R, Hakimiyan AA, Longobardi L, Ozkan H, Spagnoli A. TGF-? type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis. Sci Transl Med. 2019 05 08; 11(491). PMID: 31068441.
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    10. Chen D, Xie R, Shu B, Landay AL, Wei C, Reiser J, Spagnoli A, Torquati A, Forsyth CB, Keshavarzian A, Sumner DR. Wnt signaling in bone, kidney, intestine, and adipose tissue and interorgan interaction in aging. Ann N Y Acad Sci. 2019 04; 1442(1):48-60. PMID: 30101565.
      View in: PubMed
    11. Myers TJ, Longobardi L, Willcockson H, Temple JD, Tagliafierro L, Ye P, Li T, Esposito A, Moats-Staats BM, Spagnoli A. BMP2 Regulation of CXCL12 Cellular, Temporal, and Spatial Expression is Essential During Fracture Repair. J Bone Miner Res. 2015 Nov; 30(11):2014-27. PMID: 25967044.
      View in: PubMed
    12. Longobardi L, Li T, Tagliafierro L, Temple JD, Willcockson HH, Ye P, Esposito A, Xu F, Spagnoli A. Synovial joints: from development to homeostasis. Curr Osteoporos Rep. 2015 Feb; 13(1):41-51. PMID: 25431159.
      View in: PubMed
    13. Contaldo C, Myers TJ, Zucchini C, Manara MC, Chiodoni C, Colombo MP, Nicoletti G, Lollini PL, Li T, Longobardi L, Scotlandi K, Spagnoli A. Expression levels of insulin receptor substrate-1 modulate the osteoblastic differentiation of mesenchymal stem cells and osteosarcoma cells. Growth Factors. 2014 Feb; 32(1):41-52. PMID: 24438070.
      View in: PubMed
    14. Li T, Longobardi L, Myers TJ, Temple JD, Chandler RL, Ozkan H, Contaldo C, Spagnoli A. Joint TGF-? type II receptor-expressing cells: ontogeny and characterization as joint progenitors. Stem Cells Dev. 2013 May 01; 22(9):1342-59. PMID: 23231014.
      View in: PubMed
    15. Longobardi L, Li T, Myers TJ, O'Rear L, Ozkan H, Li Y, Contaldo C, Spagnoli A. TGF-? type II receptor/MCP-5 axis: at the crossroad between joint and growth plate development. Dev Cell. 2012 Jul 17; 23(1):71-81. PMID: 22814601.
      View in: PubMed
    16. Weis JA, Granero-Molt? F, Myers TJ, Longobardi L, Spagnoli A, Miga MI. Comparison of microCT and an inverse finite element approach for biomechanical analysis: results in a mesenchymal stem cell therapeutic system for fracture healing. J Biomech. 2012 Aug 09; 45(12):2164-70. PMID: 22766379.
      View in: PubMed
    17. Chen JG, Spagnoli A, Torquati A. Adipogenic differentiation of adipose tissue-derived human mesenchymal stem cells: effect of gastric bypass surgery. Surg Endosc. 2012 Dec; 26(12):3449-56. PMID: 22648117.
      View in: PubMed
    18. Myers TJ, Yan Y, Granero-Molto F, Weis JA, Longobardi L, Li T, Li Y, Contaldo C, Ozkan H, Ozkhan H, Spagnoli A. Systemically delivered insulin-like growth factor-I enhances mesenchymal stem cell-dependent fracture healing. Growth Factors. 2012 Aug; 30(4):230-41. PMID: 22559791.
      View in: PubMed
    19. Chen J, Spagnoli A, Torquati A. Omental gene expression of adiponectin correlates with degree of insulin sensitivity before and after gastric bypass surgery. Obes Surg. 2012 Mar; 22(3):472-7. PMID: 22161113.
      View in: PubMed
    20. Chen J, Pamuklar Z, Spagnoli A, Torquati A. Serum leptin levels are inversely correlated with omental gene expression of adiponectin and markedly decreased after gastric bypass surgery. Surg Endosc. 2012 May; 26(5):1476-80. PMID: 22179449.
      View in: PubMed
    21. Pamuklar ZN, Chen J, Muehlbauer M, Spagnoli A, Torquati A. Necdin-E2F4 interaction provides insulin-sensitizing effect after weight loss induced by gastric bypass surgery. Surg Obes Relat Dis. 2013 Jan-Feb; 9(1):94-9. PMID: 22138333.
      View in: PubMed
    22. Simmons JH, Raines M, Ness KD, Hall R, Gebretsadik T, Mohan S, Spagnoli A. Metabolic control and bone health in adolescents with type 1 diabetes. Int J Pediatr Endocrinol. 2011 Oct 26; 2011(1):13. PMID: 22029838.
      View in: PubMed
    23. Granero-Molt? F, Myers TJ, Weis JA, Longobardi L, Li T, Yan Y, Case N, Rubin J, Spagnoli A. Mesenchymal stem cells expressing insulin-like growth factor-I (MSCIGF) promote fracture healing and restore new bone formation in Irs1 knockout mice: analyses of MSCIGF autocrine and paracrine regenerative effects. Stem Cells. 2011 Oct; 29(10):1537-48. PMID: 21786367.
      View in: PubMed
    24. Myers TJ, Granero-Molto F, Longobardi L, Li T, Yan Y, Spagnoli A. Mesenchymal stem cells at the intersection of cell and gene therapy. Expert Opin Biol Ther. 2010 Dec; 10(12):1663-79. PMID: 21058931.
      View in: PubMed
    25. Li T, Longobardi L, Granero-Molto F, Myers TJ, Yan Y, Spagnoli A. Use of glycol chitosan modified by 5beta-cholanic acid nanoparticles for the sustained release of proteins during murine embryonic limb skeletogenesis. J Control Release. 2010 May 21; 144(1):101-8. PMID: 20116406.
      View in: PubMed
    26. Longobardi L, Granero-Molt? F, O'Rear L, Myers TJ, Li T, Kregor PJ, Spagnoli A. Subcellular localization of IRS-1 in IGF-I-mediated chondrogenic proliferation, differentiation and hypertrophy of bone marrow mesenchymal stem cells. Growth Factors. 2009 Oct; 27(5):309-20. PMID: 19639489.
      View in: PubMed
    27. Granero-Molt? F, Weis JA, Miga MI, Landis B, Myers TJ, O'Rear L, Longobardi L, Jansen ED, Mortlock DP, Spagnoli A. Regenerative effects of transplanted mesenchymal stem cells in fracture healing. Stem Cells. 2009 Aug; 27(8):1887-98. PMID: 19544445.
      View in: PubMed
    28. Granero-Molto F, Weis JA, Longobardi L, Spagnoli A. Role of mesenchymal stem cells in regenerative medicine: application to bone and cartilage repair. Expert Opin Biol Ther. 2008 Mar; 8(3):255-68. PMID: 18294098.
      View in: PubMed
    29. Spagnoli A, O'Rear L, Chandler RL, Granero-Molto F, Mortlock DP, Gorska AE, Weis JA, Longobardi L, Chytil A, Shimer K, Moses HL. TGF-beta signaling is essential for joint morphogenesis. J Cell Biol. 2007 Jun 18; 177(6):1105-17. PMID: 17576802.
      View in: PubMed
    30. Longobardi L, O'Rear L, Aakula S, Johnstone B, Shimer K, Chytil A, Horton WA, Moses HL, Spagnoli A. Effect of IGF-I in the chondrogenesis of bone marrow mesenchymal stem cells in the presence or absence of TGF-beta signaling. J Bone Miner Res. 2006 Apr; 21(4):626-36. PMID: 16598383.
      View in: PubMed
    31. Spagnoli A, Longobardi L, O'Rear L. Cartilage disorders: potential therapeutic use of mesenchymal stem cells. Endocr Dev. 2005; 9:17-30. PMID: 15879685.
      View in: PubMed
    32. Torquati A, O'rear L, Longobardi L, Spagnoli A, Richards WO, Daniel Beauchamp R. RUNX3 inhibits cell proliferation and induces apoptosis by reinstating transforming growth factor beta responsiveness in esophageal adenocarcinoma cells. Surgery. 2004 Aug; 136(2):310-6. PMID: 15300196.
      View in: PubMed
    33. Longobardi L, Torello M, Buckway C, O'Rear L, Horton WA, Hwa V, Roberts CT, Chiarelli F, Rosenfeld RG, Spagnoli A. A novel insulin-like growth factor (IGF)-independent role for IGF binding protein-3 in mesenchymal chondroprogenitor cell apoptosis. Endocrinology. 2003 May; 144(5):1695-702. PMID: 12697673.
      View in: PubMed
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