 Microsomes
"Microsomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Artifactual vesicles formed from the endoplasmic reticulum when cells are disrupted. They are isolated by differential centrifugation and are composed of three structural features: rough vesicles, smooth vesicles, and ribosomes. Numerous enzyme activities are associated with the microsomal fraction. (Glick, Glossary of Biochemistry and Molecular Biology, 1990; from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
| Descriptor ID |
D008861
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| MeSH Number(s) |
A11.284.835.540
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Microsomes".
Below are MeSH descriptors whose meaning is more specific than "Microsomes".
This graph shows the total number of publications written about "Microsomes" by people in this website by year, and whether "Microsomes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 1 | 1 | | 1994 | 0 | 2 | 2 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 2000 | 0 | 3 | 3 | | 2004 | 0 | 2 | 2 | | 2008 | 0 | 2 | 2 | | 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Microsomes" by people in Profiles.
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Guo T, Gillespie D, Fill M. Ryanodine receptor current amplitude controls Ca2+ sparks in cardiac muscle. Circ Res. 2012 Jun 22; 111(1):28-36.
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Zima AV, Qin J, Fill M, Blatter LA. Tricyclic antidepressant amitriptyline alters sarcoplasmic reticulum calcium handling in ventricular myocytes. Am J Physiol Heart Circ Physiol. 2008 Nov; 295(5):H2008-16.
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Qin J, Valle G, Nani A, Nori A, Rizzi N, Priori SG, Volpe P, Fill M. Luminal Ca2+ regulation of single cardiac ryanodine receptors: insights provided by calsequestrin and its mutants. J Gen Physiol. 2008 Apr; 131(4):325-34.
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Kelly JF, Storie K, Skamra C, Bienias J, Beck T, Bennett DA. Relationship between Alzheimer's disease clinical stage and Gq/11 in subcellular fractions of frontal cortex. J Neural Transm (Vienna). 2005 Aug; 112(8):1049-56.
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Rosales RA, Fill M, Escobar AL. Calcium regulation of single ryanodine receptor channel gating analyzed using HMM/MCMC statistical methods. J Gen Physiol. 2004 May; 123(5):533-53.
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Olson RD, Li X, Palade P, Shadle SE, Mushlin PS, Gambliel HA, Fill M, Boucek RJ, Cusack BJ. Sarcoplasmic reticulum calcium release is stimulated and inhibited by daunorubicin and daunorubicinol. Toxicol Appl Pharmacol. 2000 Dec 01; 169(2):168-76.
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Frank K, Tilgmann C, Shannon TR, Bers DM, Kranias EG. Regulatory role of phospholamban in the efficiency of cardiac sarcoplasmic reticulum Ca2+ transport. Biochemistry. 2000 Nov 21; 39(46):14176-82.
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Ramos-Franco J, Bare D, Caenepeel S, Nani A, Fill M, Mignery G. Single-channel function of recombinant type 2 inositol 1,4, 5-trisphosphate receptor. Biophys J. 2000 Sep; 79(3):1388-99.
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Ramos-Franco J, Fill M, Mignery GA. Isoform-specific function of single inositol 1,4,5-trisphosphate receptor channels. Biophys J. 1998 Aug; 75(2):834-9.
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Shannon TR, Bers DM. Assessment of intra-SR free [Ca] and buffering in rat heart. Biophys J. 1997 Sep; 73(3):1524-31.
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