"Podocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly differentiated epithelial cells of the visceral layer of BOWMAN CAPSULE of the KIDNEY. They are composed of a cell body with major CELL SURFACE EXTENSIONS and secondary fingerlike extensions called pedicels. They enwrap the KIDNEY GLOMERULUS capillaries with their cell surface extensions forming a filtration structure. The pedicels of neighboring podocytes interdigitate with each other leaving between them filtration slits that are bridged by an extracellular structure impermeable to large macromolecules called the slit diaphragm, and provide the last barrier to protein loss in the KIDNEY.
| Descriptor ID |
D050199
|
| MeSH Number(s) |
A05.810.453.324.359.372.650 A05.810.453.736.520.720 A11.436.720
|
| Concept/Terms |
Podocytes- Podocytes
- Podocyte
- Glomerular Visceral Epithelial Cells
- Visceral Epithelial Cells, Glomerular
- Epithelial Cells, Glomerular Visceral
|
Below are MeSH descriptors whose meaning is more general than "Podocytes".
Below are MeSH descriptors whose meaning is more specific than "Podocytes".
This graph shows the total number of publications written about "Podocytes" by people in this website by year, and whether "Podocytes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 1 | 2 |
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Below are the most recent publications written about "Podocytes" by people in Profiles.
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SuPAR mediates viral response proteinuria by rapidly changing podocyte function. Nat Commun. 2023 07 21; 14(1):4414.
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The small GTPase regulatory protein Rac1 drives podocyte injury independent of cationic channel protein TRPC5. Kidney Int. 2023 06; 103(6):1056-1062.
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Simultaneous stabilization of actin cytoskeleton in multiple nephron-specific cells protects the kidney from diverse injury. Nat Commun. 2022 05 03; 13(1):2422.
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Deiodinase-3 is a thyrostat to regulate podocyte homeostasis. EBioMedicine. 2021 Oct; 72:103617.
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From Infancy to Fancy: A Glimpse into the Evolutionary Journey of Podocytes in Culture. Kidney360. 2021 02 25; 2(2):385-397.
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Glomerular filtration barrier dysfunction in a self-limiting, RNA virus-induced glomerulopathy resembles findings in idiopathic nephrotic syndromes. Sci Rep. 2020 11 05; 10(1):19117.
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Podocyte Integrin-?3 and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy. J Am Soc Nephrol. 2020 08; 31(8):1762-1780.
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Soluble Urokinase Receptor and Acute Kidney Injury. N Engl J Med. 2020 01 30; 382(5):416-426.
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Contribution of Coiled-Coil Assembly to Ca2+/Calmodulin-Dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-Associated Phenotypes. J Am Soc Nephrol. 2019 09; 30(9):1587-1603.
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uPAR isoform 2 forms a dimer and induces severe kidney disease in mice. J Clin Invest. 2019 04 02; 129(5):1946-1959.