"Tight Junctions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell-cell junctions that seal adjacent epithelial cells together, preventing the passage of most dissolved molecules from one side of the epithelial sheet to the other. (Alberts et al., Molecular Biology of the Cell, 2nd ed, p22)
Descriptor ID |
D019108
|
MeSH Number(s) |
A11.284.149.165.420.820
|
Concept/Terms |
Tight Junctions- Tight Junctions
- Junction, Tight
- Junctions, Tight
- Tight Junction
- Zonula Occludens
- Occluden, Zonula
- Occludens, Zonula
- Zonula Occluden
- Occluding Junctions
- Junction, Occluding
- Junctions, Occluding
- Occluding Junction
|
Below are MeSH descriptors whose meaning is more general than "Tight Junctions".
Below are MeSH descriptors whose meaning is more specific than "Tight Junctions".
This graph shows the total number of publications written about "Tight Junctions" by people in this website by year, and whether "Tight Junctions" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 2 | 2 |
2007 | 1 | 1 | 2 |
2009 | 1 | 1 | 2 |
2011 | 1 | 3 | 4 |
2013 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2017 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
2021 | 0 | 1 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tight Junctions" by people in Profiles.
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Direct Action of Non-Digestible Oligosaccharides against a Leaky Gut. Nutrients. 2022 Nov 07; 14(21).
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Plasma Markers of Disrupted Gut Permeability in Severe COVID-19 Patients. Front Immunol. 2021; 12:686240.
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Enteric bacteria induce IFN? and Granzyme B from human colonic Group 1 Innate Lymphoid Cells. Gut Microbes. 2020 11 09; 12(1):1667723.
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Probiotic Bifidobacterium strains and galactooligosaccharides improve intestinal barrier function in obese adults but show no synergism when used together as synbiotics. Microbiome. 2018 06 28; 6(1):121.
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Dietary fibre-based SCFA mixtures promote both protection and repair of intestinal epithelial barrier function in a Caco-2 cell model. Food Funct. 2017 Mar 22; 8(3):1166-1173.
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Endothelial ?-Catenin Signaling Is Required for Maintaining Adult Blood-Brain Barrier Integrity and Central Nervous System Homeostasis. Circulation. 2016 Jan 12; 133(2):177-86.
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Chronic alcohol exposure renders epithelial cells vulnerable to bacterial infection. PLoS One. 2013; 8(1):e54646.
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TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions. PLoS One. 2011; 6(10):e26352.
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New molecular insights into inflammatory bowel disease-induced diarrhea. Expert Rev Gastroenterol Hepatol. 2011 Oct; 5(5):615-25.
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Pathogenic old world hantaviruses infect renal glomerular and tubular cells and induce disassembling of cell-to-cell contacts. J Virol. 2011 Oct; 85(19):9811-23.