"Gap Junctions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Connections between cells which allow passage of small molecules and electric current. Gap junctions were first described anatomically as regions of close apposition between cells with a narrow (1-2 nm) gap between cell membranes. The variety in the properties of gap junctions is reflected in the number of CONNEXINS, the family of proteins which form the junctions.
| Descriptor ID |
D017629
|
| MeSH Number(s) |
A11.284.149.165.420.471
|
| Concept/Terms |
Gap Junctions- Gap Junctions
- Gap Junction
- Junction, Gap
- Junctions, Gap
|
Below are MeSH descriptors whose meaning is more general than "Gap Junctions".
Below are MeSH descriptors whose meaning is more specific than "Gap Junctions".
This graph shows the total number of publications written about "Gap Junctions" by people in this website by year, and whether "Gap Junctions" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 3 | 1 | 4 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Gap Junctions" by people in Profiles.
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Serine-threonine protein phosphatase regulation of Cx43 dephosphorylation in arrhythmogenic disorders. Cell Signal. 2021 10; 86:110070.
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Molecular remodeling of Cx43, but not structural remodeling, promotes arrhythmias in an arrhythmogenic canine model of nonischemic heart failure. J Mol Cell Cardiol. 2021 09; 158:72-81.
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The stress kinase JNK regulates gap junction Cx43 gene expression and promotes atrial fibrillation in the aged heart. J Mol Cell Cardiol. 2018 01; 114:105-115.
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Regulation of cardiac gap junctions by protein phosphatases. J Mol Cell Cardiol. 2017 06; 107:52-57.
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Connexin40 abnormalities and atrial fibrillation in the human heart. J Mol Cell Cardiol. 2014 Nov; 76:159-68.
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Novel methods of automated quantification of gap junction distribution and interstitial collagen quantity from animal and human atrial tissue sections. PLoS One. 2014; 9(8):e104357.
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Low-intensity pulsed ultrasound (LIPUS) and cell-to-cell communication in bone marrow stromal cells. Ultrasonics. 2011 Jul; 51(5):639-44.
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Gap junction permeability: selectivity for anionic and cationic probes. Am J Physiol Cell Physiol. 2011 Mar; 300(3):C600-9.
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Decreased intercellular coupling improves the function of cardiac pacemakers derived from mouse embryonic stem cells. J Mol Cell Cardiol. 2008 Nov; 45(5):642-9.
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Phosphatidylinositol-bisphosphate regulates intercellular coupling in cardiac myocytes. Pflugers Arch. 2008 Nov; 457(2):303-13.