Transforming Growth Factor beta
"Transforming Growth Factor beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
| Descriptor ID |
D016212
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| MeSH Number(s) |
D12.644.276.374.687 D12.644.276.954.775 D12.776.467.374.687 D12.776.467.942.775 D23.529.374.687 D23.529.942.775
|
| Concept/Terms |
Transforming Growth Factor beta- Transforming Growth Factor beta
- Milk Growth Factor
- Factor, Milk Growth
- Growth Factor, Milk
- TGF-beta
- TGFbeta
- Platelet Transforming Growth Factor
- Bone-Derived Transforming Growth Factor
- Bone Derived Transforming Growth Factor
|
Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta".
This graph shows the total number of publications written about "Transforming Growth Factor beta" by people in this website by year, and whether "Transforming Growth Factor beta" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1996 | 2 | 1 | 3 |
| 1997 | 1 | 1 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 3 | 0 | 3 |
| 2001 | 1 | 1 | 2 |
| 2002 | 4 | 1 | 5 |
| 2003 | 8 | 2 | 10 |
| 2004 | 5 | 0 | 5 |
| 2005 | 13 | 1 | 14 |
| 2006 | 10 | 4 | 14 |
| 2007 | 6 | 1 | 7 |
| 2008 | 5 | 5 | 10 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 2 | 3 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 1 | 3 |
| 2013 | 2 | 0 | 2 |
| 2014 | 3 | 0 | 3 |
| 2016 | 2 | 1 | 3 |
| 2017 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transforming Growth Factor beta" by people in Profiles.
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Growth factor signalling in osteoarthritis. Growth Factors. 2018 12; 36(5-6):187-195.
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Inactivation of Cancer-Associated-Fibroblasts Disrupts Oncogenic Signaling in Pancreatic Cancer Cells and Promotes Its Regression. Cancer Res. 2018 03 01; 78(5):1321-1333.
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Degenerative Suspensory Ligament Desmitis (DSLD) in Peruvian Paso Horses Is Characterized by Altered Expression of TGF? Signaling Components in Adipose-Derived Stromal Fibroblasts. PLoS One. 2016; 11(11):e0167069.
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Sodium Benzoate, a Food Additive and a Metabolite of Cinnamon, Enriches Regulatory T Cells via STAT6-Mediated Upregulation of TGF-?. J Immunol. 2016 10 15; 197(8):3099-3110.
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Bone Morphogenetic Proteins in Lumbar Arthrodesis: What Is All the Debate About? Commentary on an article by Daniel C. Beachler, PhD, MHS, et al.: "Bone Morphogenetic Protein Use and Cancer Risk Among Patients Undergoing Lumbar Arthrodesis: A Case-Cohort Study Using the SEER-Medicare Database". J Bone Joint Surg Am. 2016 07 06; 98(13):e57.
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Combined use of low-intensity pulsed ultrasound and rhBMP-2 to enhance bone formation in a rat model of critical size defect. J Orthop Trauma. 2014 Oct; 28(10):605-11.
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Prospective, randomized, controlled trial of silicate-substituted calcium phosphate versus rhBMP-2 in a minimally invasive transforaminal lumbar interbody fusion. Spine (Phila Pa 1976). 2014 Feb 01; 39(3):185-91.
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Complications with the use of bone morphogenetic protein 2 (BMP-2) in spine surgery. Spine J. 2014 Mar 01; 14(3):552-9.
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Surgical seroma. J Neurosurg Spine. 2013 Dec; 19(6):793-4.
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Clinical sequelae after rhBMP-2 use in a minimally invasive transforaminal lumbar interbody fusion. Spine J. 2013 Sep; 13(9):1118-25.