 Nitric Oxide
"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
| Descriptor ID |
D009569
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| MeSH Number(s) |
D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
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| Concept/Terms |
Nitric Oxide- Nitric Oxide
- Oxide, Nitric
- Nitrogen Monoxide
- Monoxide, Nitrogen
- Nitric Oxide, Endothelium-Derived
- Endothelium-Derived Nitric Oxide
- Nitric Oxide, Endothelium Derived
- Endogenous Nitrate Vasodilator
- Nitrate Vasodilator, Endogenous
- Vasodilator, Endogenous Nitrate
- Mononitrogen Monoxide
- Monoxide, Mononitrogen
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Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".
This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 | | 1995 | 2 | 1 | 3 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 2 | 2 | 4 | | 1999 | 3 | 1 | 4 | | 2000 | 1 | 1 | 2 | | 2001 | 1 | 2 | 3 | | 2002 | 6 | 3 | 9 | | 2003 | 4 | 1 | 5 | | 2004 | 1 | 1 | 2 | | 2005 | 3 | 3 | 6 | | 2006 | 3 | 2 | 5 | | 2007 | 1 | 1 | 2 | | 2008 | 1 | 5 | 6 | | 2009 | 3 | 3 | 6 | | 2010 | 1 | 2 | 3 | | 2011 | 0 | 2 | 2 | | 2012 | 0 | 3 | 3 | | 2013 | 0 | 1 | 1 | | 2014 | 3 | 7 | 10 | | 2015 | 1 | 3 | 4 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nitric Oxide" by people in Profiles.
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Puglisi MP, Bradaric MJ, Pontikis J, Cabai J, Weyna T, Tednes P, Schretzman R, Rickert K, Cao Z, Andrei D. Novel primary amine diazeniumdiolates-Chemical and biological characterization. Drug Dev Res. 2018 May; 79(3):136-143.
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Frisbee JC, Butcher JT, Frisbee SJ, Olfert IM, Chantler PD, Tabone LE, d'Audiffret AC, Shrader CD, Goodwill AG, Stapleton PA, Brooks SD, Brock RW, Lombard JH. Increased peripheral vascular disease risk progressively constrains perfusion adaptability in the skeletal muscle microcirculation. Am J Physiol Heart Circ Physiol. 2016 Feb 15; 310(4):H488-504.
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Brooks SD, DeVallance E, d'Audiffret AC, Frisbee SJ, Tabone LE, Shrader CD, Frisbee JC, Chantler PD. Metabolic syndrome impairs reactivity and wall mechanics of cerebral resistance arteries in obese Zucker rats. Am J Physiol Heart Circ Physiol. 2015 Dec 01; 309(11):H1846-59.
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Chantler PD, Shrader CD, Tabone LE, d'Audiffret AC, Huseynova K, Brooks SD, Branyan KW, Grogg KA, Frisbee JC. Cerebral Cortical Microvascular Rarefaction in Metabolic Syndrome is Dependent on Insulin Resistance and Loss of Nitric Oxide Bioavailability. Microcirculation. 2015 Aug; 22(6):435-45.
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Sherer BA, Godlewski KF, Levine LA. Pharmacologic therapy for Peyronie's disease: what should we prescribe? Expert Opin Pharmacother. 2015 Jun; 16(9):1299-311.
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Kurkó J, Vida A, Ocskó T, Tryniszewska B, Rauch TA, Glant TT, Szekanecz Z, Mikecz K. Suppression of proteoglycan-induced autoimmune arthritis by myeloid-derived suppressor cells generated in vitro from murine bone marrow. PLoS One. 2014; 9(11):e111815.
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Fu J, Tobin MC, Thomas LL. Neutrophil-like low-density granulocytes are elevated in patients with moderate to severe persistent asthma. Ann Allergy Asthma Immunol. 2014 Dec; 113(6):635-640.e2.
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Kousik SM, Napier TC, Ross RD, Sumner DR, Carvey PM. Dopamine receptors and the persistent neurovascular dysregulation induced by methamphetamine self-administration in rats. J Pharmacol Exp Ther. 2014 Nov; 351(2):432-9.
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Duan L, Danzer B, Levenson VV, Maki CG. Critical roles for nitric oxide and ERK in the completion of prosurvival autophagy in 4OHTAM-treated estrogen receptor-positive breast cancer cells. Cancer Lett. 2014 Oct 28; 353(2):290-300.
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Walther S, Pluteanu F, Renz S, Nikonova Y, Maxwell JT, Yang LZ, Schmidt K, Edwards JN, Wakula P, Groschner K, Maier LS, Spiess J, Blatter LA, Pieske B, Kockskämper J. Urocortin 2 stimulates nitric oxide production in ventricular myocytes via Akt- and PKA-mediated phosphorylation of eNOS at serine 1177. Am J Physiol Heart Circ Physiol. 2014 Sep 01; 307(5):H689-700.
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