 Transcription Factor AP-1
"Transcription Factor AP-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerize in order to bind to the AP-1 recognition site, also known as the TPA-responsive element (TRE). AP-1 controls both basal and inducible transcription of several genes.
| Descriptor ID |
D018808
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| MeSH Number(s) |
D12.776.260.108.875 D12.776.930.127.875
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| Concept/Terms |
Transcription Factor AP-1- Transcription Factor AP-1
- Transcription Factor AP 1
- AP-1 Enhancer-Binding Protein
- Enhancer-Binding Protein, AP-1
- AP-1
- Activator Protein-1
- Activator Protein 1
- AP-1 Enhancer Binding Protein
- AP 1 Enhancer Binding Protein
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Below are MeSH descriptors whose meaning is more general than "Transcription Factor AP-1".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor AP-1".
This graph shows the total number of publications written about "Transcription Factor AP-1" by people in this website by year, and whether "Transcription Factor AP-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 0 | 2 | 2 | | 1999 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 1 | 1 | 2 | | 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor AP-1" by people in Profiles.
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Yan D, Kc R, Chen D, Xiao G, Im HJ. Bovine lactoferricin-induced anti-inflammation is, in part, via up-regulation of interleukin-11 by secondary activation of STAT3 in human articular cartilage. J Biol Chem. 2013 Nov 01; 288(44):31655-69.
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Hwang YH, Lee JW, Hahm ER, Jung KC, Lee JH, Park CH, Rhee HS, Ryu JM, Kim HK, Yang CH. Momordin I, an inhibitor of AP-1, suppressed osteoclastogenesis through inhibition of NF-kappaB and AP-1 and also reduced osteoclast activity and survival. Biochem Biophys Res Commun. 2005 Nov 25; 337(3):815-23.
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Jana M, Anderson JA, Saha RN, Liu X, Pahan K. Regulation of inducible nitric oxide synthase in proinflammatory cytokine-stimulated human primary astrocytes. Free Radic Biol Med. 2005 Mar 01; 38(5):655-64.
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Hahm ER, Gho YS, Park S, Park C, Kim KW, Yang CH. Synthetic curcumin analogs inhibit activator protein-1 transcription and tumor-induced angiogenesis. Biochem Biophys Res Commun. 2004 Aug 20; 321(2):337-44.
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Park S, Hahm ER, Lee DK, Yang CH. Inhibition of AP-1 transcription activator induces myc-dependent apoptosis in HL60 cells. J Cell Biochem. 2004 Apr 01; 91(5):973-86.
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Cho D, Seung Kang J, Hoon Park J, Kim YI, Hahm E, Lee J, Yang Y, Jeon J, Song H, Park H, Kim T, Pang S, Kim CW, Il Hwang Y, Jae Lee W. The enhanced IL-18 production by UVB irradiation requires ROI and AP-1 signaling in human keratinocyte cell line (HaCaT). Biochem Biophys Res Commun. 2002 Oct 25; 298(2):289-95.
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Saifuddin M, Spear GT, Chang C, Roebuck KA. Expression of MHC class II in T cells is associated with increased HIV-1 expression. Clin Exp Immunol. 2000 Aug; 121(2):324-31.
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Al-Harthi L, Roebuck KA, Olinger GG, Landay A, Sha BE, Hashemi FB, Spear GT. Bacterial vaginosis-associated microflora isolated from the female genital tract activates HIV-1 expression. J Acquir Immune Defic Syndr. 1999 Jul 01; 21(3):194-202.
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Hashemi FB, Ghassemi M, Roebuck KA, Spear GT. Activation of human immunodeficiency virus type 1 expression by Gardnerella vaginalis. J Infect Dis. 1999 Apr; 179(4):924-30.
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Al-Harthi L, Spear GT, Hashemi FB, Landay A, Sha BE, Roebuck KA. A human immunodeficiency virus (HIV)-inducing factor from the female genital tract activates HIV-1 gene expression through the kappaB enhancer. J Infect Dis. 1998 Nov; 178(5):1343-51.
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