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Duan, Lei

One or more keywords matched the following items that are connected to Duan, Lei

Item Type	Name
Concept	Adaptor Proteins, Signal Transducing
Concept	Ataxia Telangiectasia Mutated Proteins
Concept	Insulin Receptor Substrate Proteins
Concept	Proto-Oncogene Proteins c-bcl-2
Concept	Oncogene Proteins
Concept	Proto-Oncogene Proteins c-cbl
Concept	Neoplasm Proteins
Concept	Proto-Oncogene Proteins c-mdm2
Concept	Retroviridae Proteins, Oncogenic
Concept	Proto-Oncogene Proteins
Concept	HSP90 Heat-Shock Proteins
Concept	Proto-Oncogene Proteins c-akt
Concept	Microtubule-Associated Proteins
Concept	Proto-Oncogene Proteins c-vav
Academic Article	Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis.
Academic Article	Cbl-mediated ubiquitinylation and negative regulation of Vav.
Academic Article	The Cbl family and other ubiquitin ligases: destructive forces in control of antigen receptor signaling.
Academic Article	A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLCgamma1 activation and angiogenesis.
Academic Article	Binding of Cbl to a phospholipase Cgamma1-docking site on platelet-derived growth factor receptor beta provides a dual mechanism of negative regulation.
Academic Article	Overexpression of RhoA induces preneoplastic transformation of primary mammary epithelial cells.
Academic Article	Distinct roles for Rho versus Rac/Cdc42 GTPases downstream of Vav2 in regulating mammary epithelial acinar architecture.
Academic Article	Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration.
Academic Article	Prolylcarboxypeptidase regulates proliferation, autophagy, and resistance to 4-hydroxytamoxifen-induced cytotoxicity in estrogen receptor-positive breast cancer cells.
Academic Article	Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers.
Academic Article	The prolyl peptidases PRCP/PREP regulate IRS-1 stability critical for rapamycin-induced feedback activation of PI3K and AKT.
Academic Article	Critical roles for nitric oxide and ERK in the completion of prosurvival autophagy in 4OHTAM-treated estrogen receptor-positive breast cancer cells.
Academic Article	Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
Academic Article	p53-regulated autophagy is controlled by glycolysis and determines cell fate.
Academic Article	Modeling the Etiology of p53-mutated Cancer Cells.
Academic Article	Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor.
Academic Article	The IGF-1R/AKT pathway has opposing effects on Nutlin-3a-induced apoptosis.
Academic Article	p53 promotes AKT and SP1-dependent metabolism through the pentose phosphate pathway that inhibits apoptosis in response to Nutlin-3a.
Academic Article	DZNep represses Bcl-2 expression and modulates apoptosis sensitivity in response to Nutlin-3a.
Academic Article	JMJD2 promotes acquired cisplatin resistance in non-small cell lung carcinoma cells.
Academic Article	The histone demethylase JMJD2B is critical for p53-mediated autophagy and survival in Nutlin-treated cancer cells.
Academic Article	Prolyl endopeptidase inhibitor Y-29794 blocks the IRS1-AKT-mTORC1 pathway and inhibits survival and in vivo tumor growth of triple-negative breast cancer.
Academic Article	Fatty acid oxidation and autophagy promote endoxifen resistance and counter the effect of AKT inhibition in ER-positive breast cancer cells.
Academic Article	Mixed lineage kinase 3 and CD70 cooperation sensitize trastuzumab-resistant HER2+ breast cancer by ceramide-loaded nanoparticles.
Concept	Autophagy-Related Proteins

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Proteins