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The IGF-1R/AKT pathway has opposing effects on Nutlin-3a-induced apoptosis.
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The IGF-1R/AKT pathway has opposing effects on Nutlin-3a-induced apoptosis.
The IGF-1R/AKT pathway has opposing effects on Nutlin-3a-induced apoptosis. Cancer Biol Ther. 2017 Nov 02; 18(11):895-903.
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PubMed
subject areas
Antineoplastic Agents
Apoptosis
Bone Neoplasms
Cell Line, Tumor
Cisplatin
Drug Resistance, Neoplasm
Drug Synergism
Heterocyclic Compounds, 3-Ring
Humans
Imidazoles
Osteosarcoma
Piperazines
Protein Kinase Inhibitors
Proto-Oncogene Proteins c-akt
Pyrazines
Receptor, IGF Type 1
Receptors, Somatomedin
authors with profiles
Carl Maki
Steven Gitelis
Lei Duan