"Oligonucleotide Probes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.
| Descriptor ID |
D015345
|
| MeSH Number(s) |
D13.444.600.601 D27.505.259.750.600.650 D27.720.470.530.600.650
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Oligonucleotide Probes".
Below are MeSH descriptors whose meaning is more specific than "Oligonucleotide Probes".
This graph shows the total number of publications written about "Oligonucleotide Probes" by people in this website by year, and whether "Oligonucleotide Probes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Oligonucleotide Probes" by people in Profiles.
-
Factors affecting PCR-mediated recombination. Environ Microbiol. 2002 Aug; 4(8):482-6.
-
Expression of matrix metalloproteinases in normal and damaged articular cartilage from human knee and ankle joints. Lab Invest. 1999 Dec; 79(12):1669-77.
-
Modulation of bone morphogenetic protein-2 and bone morphogenetic protein-4 gene expression in osteoblastic cell lines. Cell Mol Biol (Noisy-le-grand). 1998 Dec; 44(8):1237-46.
-
p53 gene mutations in radiation-induced thyroid cancer. J Clin Endocrinol Metab. 1996 Aug; 81(8):3039-44.
-
PCR production of a digoxigenin-labeled probe for the detection of human cytomegalovirus in tissue sections. Diagn Mol Pathol. 1994 Sep; 3(3):200-8.
-
Phenol hydroxylase from Trichosporon cutaneum: gene cloning, sequence analysis, and functional expression in Escherichia coli. J Bacteriol. 1992 Nov; 174(22):7112-20.
-
Conversion of the lac repressor into an allosterically regulated transcriptional activator for mammalian cells. Mol Cell Biol. 1990 Jul; 10(7):3343-56.
-
The adenovirus E4 17-kilodalton protein complexes with the cellular transcription factor E2F, altering its DNA-binding properties and stimulating E1A-independent accumulation of E2 mRNA. J Virol. 1990 May; 64(5):2345-59.