"Interleukin-13" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine synthesized by T-LYMPHOCYTES that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B-LYMPHOCYTES. It appears to play a role in regulating inflammatory and immune responses.
| Descriptor ID |
D018793
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| MeSH Number(s) |
D12.644.276.374.465.513 D12.776.467.374.465.513 D23.529.374.465.513
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-13".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-13".
This graph shows the total number of publications written about "Interleukin-13" by people in this website by year, and whether "Interleukin-13" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2005 | 0 | 2 | 2 |
| 2008 | 1 | 1 | 2 |
| 2010 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-13" by people in Profiles.
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Targeting interleukin (IL)-4/IL-13 in immune checkpoint inhibitor-induced bullous pemphigoid: a cautionary note on the beneficial effect of T helper 2 immunity in melanoma and immunotherapy. Br J Dermatol. 2023 Dec 20; 190(1):137-138.
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Protection against Staphylococcus aureus bacteremia-induced mortality depends on ILC2s and eosinophils. JCI Insight. 2019 03 21; 4(6).
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12/15-lipoxygenase is an interleukin-13 and interferon-? counterregulated-mediator of allergic airway inflammation. Mediators Inflamm. 2010; 2010.
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Expression of IL-4 receptor alpha on smooth muscle cells is not necessary for development of experimental allergic asthma. J Allergy Clin Immunol. 2010 Aug; 126(2):347-54.
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Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages. FASEB J. 2008 Nov; 22(11):4022-32.
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Interleukin-4, interleukin-13, signal transducer and activator of transcription factor 6, and allergic asthma. Curr Mol Med. 2008 Aug; 8(5):384-92.
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IL-4 receptor signaling in Clara cells is required for allergen-induced mucus production. J Immunol. 2005 Sep 15; 175(6):3746-52.
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Dissecting asthma using focused transgenic modeling and functional genomics. J Allergy Clin Immunol. 2005 Aug; 116(2):305-11.
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Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat Med. 2002 Aug; 8(8):885-9.
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Keratinocyte CDw60 expression is modulated by both a Th-1 type cytokine IFN-gamma and Th-2 cytokines IL-4 and IL-13: relevance to psoriasis. J Invest Dermatol. 2001 Feb; 116(2):305-12.