"Apolipoprotein L1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ApoL protein highly expressed by the liver. It has anti-trypanosomal activity through its ability to permeabilize TRYPANOSOMA membranes. Mutations in the APOL1 gene are associated with type 4 FOCAL SEGMENTAL GLOMERULOSCLEROSIS .
| Descriptor ID |
D000075944
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| MeSH Number(s) |
D10.532.091.750.500 D12.776.070.400.750.500 D12.776.521.120.750.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Apolipoprotein L1".
Below are MeSH descriptors whose meaning is more specific than "Apolipoprotein L1".
This graph shows the total number of publications written about "Apolipoprotein L1" by people in this website by year, and whether "Apolipoprotein L1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Apolipoprotein L1" by people in Profiles.
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Soluble Urokinase-Type Plasminogen Activator Receptor in Black Americans with CKD. Clin J Am Soc Nephrol. 2018 07 06; 13(7):1013-1021.
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A tripartite complex of suPAR, APOL1 risk variants and av?3 integrin on podocytes mediates chronic kidney disease. Nat Med. 2017 Aug; 23(8):945-953.
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Clinical Features and Histology of Apolipoprotein L1-Associated Nephropathy in the FSGS Clinical Trial. J Am Soc Nephrol. 2015 Jun; 26(6):1443-8.
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APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy. J Am Soc Nephrol. 2011 Nov; 22(11):2129-37.