Receptors, Interleukin-12
"Receptors, Interleukin-12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors for INTERLEUKIN-12. They exist as dimers of beta 1 and beta 2 subunits. Signaling from interleukin-12 receptors occurs through their interaction with JANUS KINASES.
| Descriptor ID |
D053707
|
| MeSH Number(s) |
D12.776.543.750.705.852.420.580
|
| Concept/Terms |
Receptors, Interleukin-12- Receptors, Interleukin-12
- Receptors, Interleukin 12
- Interleukin-12 Receptor
- Interleukin 12 Receptor
- IL-12 Receptor
- IL 12 Receptor
- Receptor, IL-12
- Receptor, Interleukin-12
- Receptor, Interleukin 12
- IL-12 Receptors
- IL 12 Receptors
- Receptors, IL-12
- Interleukin-12 Receptors
- Interleukin 12 Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Interleukin-12".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Interleukin-12".
This graph shows the total number of publications written about "Receptors, Interleukin-12" by people in this website by year, and whether "Receptors, Interleukin-12" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 2 | 2 |
| 2009 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Interleukin-12" by people in Profiles.
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IL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12R?1 internalization and suppress EAE. Proc Natl Acad Sci U S A. 2020 09 01; 117(35):21557-21567.
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Interleukin-12 (IL-12), but not IL-23, induces the expression of IL-7 in microglia and macrophages: implications for multiple sclerosis. Immunology. 2014 Apr; 141(4):549-63.
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IL-12 p40 homodimer, the so-called biologically inactive molecule, induces nitric oxide synthase in microglia via IL-12R beta 1. Glia. 2009 Nov 01; 57(14):1553-65.
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Suppression of regulatory T cells by IL-12p40 homodimer via nitric oxide. J Immunol. 2009 Aug 01; 183(3):2045-58.
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IL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages. Mol Immunol. 2009 Feb; 46(5):773-83.
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Induction of lymphotoxin-alpha by interleukin-12 p40 homodimer, the so-called biologically inactive molecule, but not IL-12 p70. Immunology. 2009 Jul; 127(3):312-25.