Phosphatidylinositol Diacylglycerol-Lyase
"Phosphatidylinositol Diacylglycerol-Lyase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphorus-oxygen lyase found primarily in BACTERIA. The enzyme catalyzes the cleavage of a phosphoester linkage in 1-phosphatidyl-1D-myo-inositol to form 1D-myo-inositol 1,2-cyclic phosphate and diacylglycerol. The enzyme was formerly classified as a phosphoric diester hydrolase (EC 3.1.4.10) and is often referred to as a TYPE C PHOSPHOLIPASES. However it is now known that a cyclic phosphate is the final product of this enzyme and that water does not enter into the reaction.
| Descriptor ID |
D043265
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| MeSH Number(s) |
D08.811.277.352.640.700.700.500 D08.811.520.650.800
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| Concept/Terms |
Phosphatidylinositol Diacylglycerol-Lyase- Phosphatidylinositol Diacylglycerol-Lyase
- Diacylglycerol-Lyase, Phosphatidylinositol
- Phosphatidylinositol Diacylglycerol Lyase
- Monophosphatidylinositol Phosphodiesterase
- Phosphodiesterase, Monophosphatidylinositol
- 1-Phosphatidylinositol Phosphodiesterase
- 1 Phosphatidylinositol Phosphodiesterase
- Phosphodiesterase, 1-Phosphatidylinositol
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Below are MeSH descriptors whose meaning is more general than "Phosphatidylinositol Diacylglycerol-Lyase".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidylinositol Diacylglycerol-Lyase".
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Below are the most recent publications written about "Phosphatidylinositol Diacylglycerol-Lyase" by people in Profiles.
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Chondrocyte-mediated catabolism of aggrecan: evidence for a glycosylphosphatidylinositol-linked protein in the aggrecanase response to interleukin-1 or retinoic acid. Arch Biochem Biophys. 1999 Jul 15; 367(2):258-64.
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Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1. J Exp Med. 1995 Aug 01; 182(2):501-9.